1MLF
| |
1MLK
| |
1MLO
| |
1MLL
| |
1MLQ
| |
1MLS
| |
1MLG
| |
4DIJ
| |
3HO0
| Crystal structure of the PPARgamma-LBD complexed with a new aryloxy-3phenylpropanoic acid | Descriptor: | (2S)-2-(4-phenethylphenoxy)-3-phenyl-propanoic acid, Peroxisome proliferator-activated receptor gamma | Authors: | Pochetti, G, Montanari, R, Mazza, F, Loiodice, F, Fracchiolla, G, Laghezza, A, Lavecchia, A, Novellino, E. | Deposit date: | 2009-06-01 | Release date: | 2009-10-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | New 2-Aryloxy-3-phenyl-propanoic Acids As Peroxisome Proliferator-Activated Receptors alpha/gamma Dual Agonists with Improved Potency and Reduced Adverse Effects on Skeletal Muscle Function J.Med.Chem., 52, 2009
|
|
4CDJ
| Structure of ZNRF3 ectodomain | Descriptor: | 1,2-ETHANEDIOL, E3 UBIQUITIN-PROTEIN LIGASE ZNRF3, FORMIC ACID | Authors: | Peng, W.C, de Lau, W, Madoori, P.K, Forneris, F, Granneman, J.C.M, Clevers, H, Gros, P. | Deposit date: | 2013-11-01 | Release date: | 2014-01-08 | Last modified: | 2019-04-03 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structures of Wnt-Antagonist Znrf3 and its Complex with R-Spondin 1 and Implications for Signaling. Plos One, 8, 2013
|
|
2ZK4
| Human peroxisome proliferator-activated receptor gamma ligand binding domain complexed with 15-oxo-eicosatetraenoic acid | Descriptor: | (5E,8E,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic acid, Peroxisome proliferator-activated receptor gamma | Authors: | Waku, T, Shiraki, T, Oyama, T, Fujimoto, Y, Morikawa, K. | Deposit date: | 2008-03-12 | Release date: | 2009-02-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids J.Mol.Biol., 385, 2009
|
|
4CDK
| Structure of ZNRF3-RSPO1 | Descriptor: | E3 UBIQUITIN-PROTEIN LIGASE ZNRF3, R-SPONDIN-1 | Authors: | Peng, W.C, de Lau, W, Madoori, P.K, Forneris, F, Granneman, J.C.M, Clevers, H, Gros, P. | Deposit date: | 2013-11-01 | Release date: | 2014-01-08 | Last modified: | 2019-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structures of Wnt-Antagonist Znrf3 and its Complex with R-Spondin 1 and Implications for Signaling. Plos One, 8, 2013
|
|
1MLM
| |
1MLH
| |
1MLR
| |
2ZK3
| Human peroxisome proliferator-activated receptor gamma ligand binding domain complexed with 8-oxo-eicosatetraenoic acid | Descriptor: | (5E,11E,14E)-8-oxoicosa-5,9,11,14-tetraenoic acid, Peroxisome proliferator-activated receptor gamma | Authors: | Waku, T, Shiraki, T, Oyama, T, Fujimoto, Y, Morikawa, K. | Deposit date: | 2008-03-12 | Release date: | 2009-02-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids J.Mol.Biol., 385, 2009
|
|
6QK1
| |
8GTK
| |
6QJV
| |
8GTJ
| |
4NDA
| Crystal structure of 3-nitro-tyrosine tRNA synthetase (5B) bound to 3-nitro-tyrosine | Descriptor: | GLYCEROL, META-NITRO-TYROSINE, SODIUM ION, ... | Authors: | Cooley, R.B, Driggers, C.M, Karplus, P.A, Mehl, R.A. | Deposit date: | 2013-10-25 | Release date: | 2014-03-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Basis of Improved Second-Generation 3-Nitro-tyrosine tRNA Synthetases. Biochemistry, 53, 2014
|
|
4ND6
| Crystal structure of apo 3-nitro-tyrosine tRNA synthetase (5B) in the open form | Descriptor: | GLYCEROL, Tyrosine-tRNA ligase | Authors: | Cooley, R.B, Driggers, C.M, Karplus, P.A, Mehl, R.A. | Deposit date: | 2013-10-25 | Release date: | 2014-03-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis of Improved Second-Generation 3-Nitro-tyrosine tRNA Synthetases. Biochemistry, 53, 2014
|
|
8T3W
| Structure of Bre1-nucleosome complex - state2 | Descriptor: | 601 DNA strand 1, 601 DNA strand 2, E3 ubiquitin-protein ligase BRE1, ... | Authors: | Zhao, F, Hicks, C.W, Wolberger, C. | Deposit date: | 2023-06-07 | Release date: | 2023-10-18 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Mechanism of histone H2B monoubiquitination by Bre1. Nat.Struct.Mol.Biol., 30, 2023
|
|
6LPF
| The crystal structure of human cytoplasmic LRS | Descriptor: | 2'-(L-NORVALYL)AMINO-2'-DEOXYADENOSINE, 5'-O-(L-leucylsulfamoyl)adenosine, GLYCEROL, ... | Authors: | Liu, R.J, Long, T, Li, H, Li, J, Zhao, J.H, Lin, J.Z, Palencia, A, Wang, M.Z, Cusack, S, Wang, E.D. | Deposit date: | 2020-01-10 | Release date: | 2020-03-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond. Nucleic Acids Res., 48, 2020
|
|
8JRU
| Cryo-EM structure of the glucagon receptor bound to beta-arrestin 1 in ligand-free state | Descriptor: | Beta-arrestin 1 and single-chain fragment variable 30 (scFv30), HA signal peptide,HPC4 purification tag,Glucagon receptor,C-terminal tail of Vasopressin V2 receptor, Nanobody 32, ... | Authors: | Chen, K, Zhang, C, Lin, S, Zhao, Q, Wu, B. | Deposit date: | 2023-06-17 | Release date: | 2023-08-16 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Tail engagement of arrestin at the glucagon receptor. Nature, 620, 2023
|
|