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8CZI
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BU of 8czi by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with extended HR2
Descriptor: Scaffolded Spike protein S2' HR1, Spike protein S2' HR2
Authors:Yang, K, Brunger, A.T.
Deposit date:2022-05-24
Release date:2022-09-07
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.22 Å)
Cite:Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein.
Proc.Natl.Acad.Sci.USA, 119, 2022
8D27
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BU of 8d27 by Molmil
Arginase Domain of Ornithine Decarboxylase/Arginase from Fusobacterium nucleatum
Descriptor: Arginase
Authors:Chan, A.C, Kolesnikov, M, Murphy, M.E.
Deposit date:2022-05-27
Release date:2022-07-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Sequence Divergence in the Arginase Domain of Ornithine Decarboxylase/Arginase in Fusobacteriacea Leads to Loss of Function in Oral Associated Species.
Biochemistry, 61, 2022
7ZH6
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BU of 7zh6 by Molmil
Structure of human OCT3 in complex with inhibitor Corticosterone
Descriptor: CORTICOSTERONE, Solute carrier family 22 member 3
Authors:Khanppnavar, B, Korkhov, V.
Deposit date:2022-04-05
Release date:2022-11-09
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Structural basis of organic cation transporter-3 inhibition.
Nat Commun, 13, 2022
7ZH0
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BU of 7zh0 by Molmil
Structure of human OCT3 in lipid nanodisc
Descriptor: Solute carrier family 22 member 3
Authors:Khanppnavar, B, Korkhov, V, Qi, C.
Deposit date:2022-04-05
Release date:2022-11-09
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of organic cation transporter-3 inhibition.
Nat Commun, 13, 2022
7ZOU
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BU of 7zou by Molmil
Crystal structure of Synechocystis halorhodopsin (SyHR), Cl-pumping mode, ground state
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, EICOSANE, ...
Authors:Kovalev, K, Bukhdruker, S, Astashkin, R, Vaganova, S, Gordeliy, V.
Deposit date:2022-04-26
Release date:2022-11-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural insights into light-driven anion pumping in cyanobacteria.
Nat Commun, 13, 2022
6ON4
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BU of 6on4 by Molmil
Crystal structure of the GntR-type sialoregulator NanR from Escherichia coli, in complex with sialic acid
Descriptor: HTH-type transcriptional repressor NanR, N-acetyl-beta-neuraminic acid, ZINC ION, ...
Authors:Horne, C.R, Panjikar, S, North, R.A, Dobson, R.C.J.
Deposit date:2019-04-19
Release date:2020-07-08
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Control of the Escherichia coli sialoregulon by transcriptional repressor NanR.
J. Bacteriol., 195, 2013
6ONY
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BU of 6ony by Molmil
BRD2_Bromodomain1 complex with inhibitor 744
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 2, N-ethyl-4-[2-(4-fluoro-2,6-dimethylphenoxy)-5-(2-hydroxypropan-2-yl)phenyl]-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide
Authors:Longenecker, K.L, Bigelow, L.
Deposit date:2019-04-22
Release date:2020-01-29
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer.
Nature, 578, 2020
3FTP
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BU of 3ftp by Molmil
Crystal structure of 3-Ketoacyl-(acyl-carrier-protein) reductase from Burkholderia pseudomallei at 2.05 A resolution
Descriptor: 3-oxoacyl-[acyl-carrier protein] reductase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-01-13
Release date:2009-01-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Combining functional and structural genomics to sample the essential Burkholderia structome.
Plos One, 8, 2013
7ZOW
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BU of 7zow by Molmil
Crystal structure of Synechocystis halorhodopsin (SyHR), Cl-pumping mode, O state
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, EICOSANE, OLEIC ACID, ...
Authors:Kovalev, K, Bukhdruker, S, Astashkin, R, Vaganova, S, Gordeliy, V.
Deposit date:2022-04-26
Release date:2022-11-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into light-driven anion pumping in cyanobacteria.
Nat Commun, 13, 2022
7ZOV
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BU of 7zov by Molmil
Crystal structure of Synechocystis halorhodopsin (SyHR), Cl-pumping mode, K state
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, EICOSANE, ...
Authors:Kovalev, K, Bukhdruker, S, Astashkin, R, Vaganova, S, Gordeliy, V.
Deposit date:2022-04-26
Release date:2022-11-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into light-driven anion pumping in cyanobacteria.
Nat Commun, 13, 2022
7ZHA
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BU of 7zha by Molmil
Structure of human OCT3 in complex with inhibitor decynium-22
Descriptor: 1-ethyl-2-[(1-ethylquinolin-2-yl)methyl]quinoline, Solute carrier family 22 member 3
Authors:Khanppnavar, B, Korkhov, V.
Deposit date:2022-04-05
Release date:2022-11-09
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Structural basis of organic cation transporter-3 inhibition.
Nat Commun, 13, 2022
7ZOY
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BU of 7zoy by Molmil
Crystal structure of Synechocystis halorhodopsin (SyHR), SO4-bound form, ground state
Descriptor: CHLORIDE ION, EICOSANE, GLYCEROL, ...
Authors:Kovalev, K, Bukhdruker, S, Astashkin, R, Vaganova, S, Gordeliy, V.
Deposit date:2022-04-26
Release date:2022-11-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structural insights into light-driven anion pumping in cyanobacteria.
Nat Commun, 13, 2022
7ZSC
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BU of 7zsc by Molmil
Crystal structure of the heterodimeric human C-P4H-II with truncated alpha subunit (C-P4H-II delta281)
Descriptor: Prolyl 4-hydroxylase subunit alpha-2, Protein disulfide-isomerase, SULFATE ION
Authors:Lebedev, A, Koski, M.K, Wierenga, R.K, Murthy, A.V, Sulu, R.
Deposit date:2022-05-06
Release date:2022-11-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.85 Å)
Cite:Crystal structure of the collagen prolyl 4-hydroxylase (C-P4H) catalytic domain complexed with PDI: Toward a model of the C-P4H alpha 2 beta 2 tetramer.
J.Biol.Chem., 298, 2022
6OMN
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BU of 6omn by Molmil
Glycosylated BMP2 homodimer
Descriptor: Bone morphogenetic protein 2, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Juo, Z.S, Seeherman, H.
Deposit date:2019-04-19
Release date:2019-05-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix.
Sci Transl Med, 11, 2019
1KLF
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BU of 1klf by Molmil
FIMH ADHESIN-FIMC CHAPERONE COMPLEX WITH D-MANNOSE
Descriptor: CHAPERONE PROTEIN FIMC, FIMH PROTEIN, alpha-D-mannopyranose
Authors:Hung, C.S, Bouckaert, J.
Deposit date:2001-12-11
Release date:2002-06-05
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection.
Mol.Microbiol., 44, 2002
6O63
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BU of 6o63 by Molmil
Crystal Structure of Arabidopsis thaliana Spermidine Synthase isoform 1 (AtSPDS1)
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, SULFATE ION, ...
Authors:Sekula, B, Dauter, Z.
Deposit date:2019-03-05
Release date:2019-06-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Spermidine Synthase (SPDS) Undergoes Concerted Structural Rearrangements Upon Ligand Binding - A Case Study of the Two SPDS Isoforms FromArabidopsis thaliana.
Front Plant Sci, 10, 2019
6ORE
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BU of 6ore by Molmil
Release complex 70S
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Fu, Z.
Deposit date:2019-04-30
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OVB
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BU of 6ovb by Molmil
Crystal structure of a Bacillus thuringiensis Cry1Da tryptic core variant
Descriptor: Active core crystal toxin protein 1D
Authors:Rydel, T.J, Halls, C, Evdokimov, A.G, Beishir, S.C.
Deposit date:2019-05-07
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.611 Å)
Cite:Bacillus thuringiensis Cry1Da_7 and Cry1B.868 Protein Interactions with Novel Receptors Allow Control of Resistant Fall Armyworms, Spodoptera frugiperda (J.E. Smith).
Appl.Environ.Microbiol., 85, 2019
1RUT
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BU of 1rut by Molmil
Complex of LMO4 LIM domains 1 and 2 with the ldb1 LID domain
Descriptor: Fusion protein of Lmo4 protein and LIM domain-binding protein 1, ZINC ION
Authors:Deane, J.E, Ryan, D.P, Maher, M.J, Kwan, A.H.Y, Bacca, M, Mackay, J.P, Guss, J.M, Visvader, J.E, Matthews, J.M.
Deposit date:2003-12-11
Release date:2004-10-12
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Tandem LIM domains provide synergistic binding in the LMO4:Ldb1 complex
Embo J., 23, 2004
1RVF
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BU of 1rvf by Molmil
FAB COMPLEXED WITH INTACT HUMAN RHINOVIRUS
Descriptor: FAB 17-IA, HUMAN RHINOVIRUS 14 COAT PROTEIN
Authors:Smith, T.J.
Deposit date:1996-09-05
Release date:1998-02-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (4 Å)
Cite:Neutralizing antibody to human rhinovirus 14 penetrates the receptor-binding canyon.
Nature, 383, 1996
3G4Z
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BU of 3g4z by Molmil
Crystal Structure of NiSOD Y9F mutant at 1.9 A
Descriptor: BROMIDE ION, NICKEL (II) ION, Superoxide dismutase [Ni]
Authors:Garman, S.C, Guce, A.I, Herbst, R.W, Bryngelson, P.A, Cabelli, D.E, Higgins, K.A, Ryan, K.C, Maroney, M.J.
Deposit date:2009-02-04
Release date:2009-04-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Role of conserved tyrosine residues in NiSOD catalysis: a case of convergent evolution
Biochemistry, 48, 2009
8AE6
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BU of 8ae6 by Molmil
Cryo-EM structure of the SEA complex wing (SEACIT)
Descriptor: Maintenance of telomere capping protein 5, Nitrogen permease regulator 2, Nitrogen permease regulator 3, ...
Authors:Tafur, L, Loewith, R.
Deposit date:2022-07-12
Release date:2022-11-02
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Cryo-EM structure of the SEA complex.
Nature, 611, 2022
8C3U
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BU of 8c3u by Molmil
Crystal Structure of human IL-1beta in complex with a low molecular weight antagonist
Descriptor: (S)-4'-hydroxy-3'-(6-methyl-2-oxo-3-(1H-pyrazol-4-yl)indolin-3-yl)-[1,1'-biphenyl]-2,4-dicarboxylic acid, Interleukin-1 beta
Authors:Rondeau, J.-M, Lehmann, S, Koch, E.
Deposit date:2022-12-28
Release date:2023-09-13
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.945 Å)
Cite:Discovery of a selective and biologically active low-molecular weight antagonist of human interleukin-1 beta.
Nat Commun, 14, 2023
2W88
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BU of 2w88 by Molmil
Plastocyanin variant with N-terminal Methionine - open structure
Descriptor: COPPER (II) ION, PLASTOCYANIN, ZINC ION
Authors:Crowley, P.B, Matias, P.M, Khan, A.R.
Deposit date:2009-01-14
Release date:2009-10-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Metal-Mediated Self-Assembly of a Beta-Sandwich Protein.
Chemistry, 15, 2009
3HWK
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BU of 3hwk by Molmil
Crystal structure of methylcitrate synthase from Mycobacterium tuberculosis
Descriptor: Methylcitrate synthase, SUCCINIC ACID
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-06-17
Release date:2009-06-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015

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