7YG5
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6FPY
| Inter-alpha-inhibitor heavy chain 1, wild type | 分子名称: | GLYCEROL, Inter-alpha-trypsin inhibitor heavy chain H1, MAGNESIUM ION | 著者 | Briggs, D.C, Day, A.J. | 登録日 | 2018-02-12 | 公開日 | 2019-02-27 | 最終更新日 | 2020-03-18 | 実験手法 | X-RAY DIFFRACTION (2.339 Å) | 主引用文献 | Inter-alpha-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation J.Biol.Chem., 2020
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6FPZ
| Inter-alpha-inhibitor heavy chain 1, D298A | 分子名称: | ACETATE ION, GLYCEROL, Inter-alpha-trypsin inhibitor heavy chain H1 | 著者 | Briggs, D.C, Day, A.J. | 登録日 | 2018-02-12 | 公開日 | 2019-02-27 | 最終更新日 | 2020-03-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Inter-alpha-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation J.Biol.Chem., 2020
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7ZWH
| VWF Tubules of D1D2 and D'D3A1 domains | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Javitt, G, Fass, D. | 登録日 | 2022-05-19 | 公開日 | 2022-07-13 | 最終更新日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Assembly of von Willebrand factor tubules with in vivo helical parameters requires A1 domain insertion. Blood, 140, 2022
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5GJV
| Structure of the mammalian voltage-gated calcium channel Cav1.1 complex at near atomic resolution | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wu, J.P, Yan, Z, Li, Z.Q, Zhou, Q, Yan, N. | 登録日 | 2016-07-02 | 公開日 | 2016-09-14 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure of the voltage-gated calcium channel Cav1.1 at 3.6 angstrom resolution Nature, 537, 2016
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5GJW
| Structure of the mammalian voltage-gated calcium channel Cav1.1 complex for ClassII map | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wu, J.P, Yan, Z, Li, Z.Q, Zhou, Q, Yan, N. | 登録日 | 2016-07-02 | 公開日 | 2016-09-14 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structure of the voltage-gated calcium channel Cav1.1 at 3.6 angstrom resolution Nature, 537, 2016
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7N1O
| The von Willebrand factor A domain of human capillary morphogenesis gene II, flexibly fused to the 1TEL crystallization chaperone | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Transcription factor ETV6,Isoform 4 of Anthrax toxin receptor 2 | 著者 | Mathis, M.H, Bezzant, B.D, Ramirez, D.T, Sarath Nawarathnage, S.D, Doukov, T, Moody, J.D. | 登録日 | 2021-05-27 | 公開日 | 2021-06-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | Crystals of TELSAM-target protein fusions that exhibit minimal crystal contacts and lack direct inter-TELSAM contacts. Open Biology, 12, 2022
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7MIY
| Human N-type voltage-gated calcium channel Cav2.2 at 3.1 Angstrom resolution | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yan, N, Gao, S, Yao, X. | 登録日 | 2021-04-18 | 公開日 | 2021-07-07 | 最終更新日 | 2021-08-18 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure of human Ca v 2.2 channel blocked by the painkiller ziconotide. Nature, 596, 2021
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7MIX
| Human N-type voltage-gated calcium channel Cav2.2 in the presence of ziconotide at 3.0 Angstrom resolution | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yan, N, Gao, S, Yao, X. | 登録日 | 2021-04-18 | 公開日 | 2021-07-07 | 最終更新日 | 2021-08-18 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure of human Ca v 2.2 channel blocked by the painkiller ziconotide. Nature, 596, 2021
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6JP5
| Rabbit Cav1.1-Nifedipine Complex | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhao, Y, Huang, G, Wu, J, Yan, N. | 登録日 | 2019-03-25 | 公開日 | 2019-06-12 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Molecular Basis for Ligand Modulation of a Mammalian Voltage-Gated Ca2+Channel. Cell, 177, 2019
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6JP8
| Rabbit Cav1.1-Bay K8644 Complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhao, Y, Huang, G, Wu, J, Yan, N. | 登録日 | 2019-03-26 | 公開日 | 2019-06-12 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Molecular Basis for Ligand Modulation of a Mammalian Voltage-Gated Ca2+Channel. Cell, 177, 2019
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6JPB
| Rabbit Cav1.1-Diltiazem Complex | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhao, Y, Huang, G, Wu, J, Yan, N. | 登録日 | 2019-03-26 | 公開日 | 2019-06-12 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Molecular Basis for Ligand Modulation of a Mammalian Voltage-Gated Ca2+Channel. Cell, 177, 2019
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6JPA
| Rabbit Cav1.1-Verapamil Complex | 分子名称: | (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... | 著者 | Zhao, Y, Huang, G, Wu, J, Yan, N. | 登録日 | 2019-03-26 | 公開日 | 2019-06-12 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Molecular Basis for Ligand Modulation of a Mammalian Voltage-Gated Ca2+Channel. Cell, 177, 2019
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5BV8
| G1324S mutation in von Willebrand Factor A1 domain | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, von Willebrand factor | 著者 | Campbell, J.C, Kim, C, Tischer, A, Auton, M. | 登録日 | 2015-06-04 | 公開日 | 2015-12-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Mutational Constraints on Local Unfolding Inhibit the Rheological Adaptation of von Willebrand Factor. J.Biol.Chem., 291, 2016
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2ADF
| Crystal Structure and Paratope Determination of 82D6A3, an Antithrombotic Antibody Directed Against the von Willebrand factor A3-Domain | 分子名称: | 82D6A3 IgG, ACETIC ACID, GLYCEROL, ... | 著者 | Staelens, S, Hadders, M.A, Vauterin, S, Platteau, C, Vanhoorelbeke, K, Huizinga, E.G, Deckmyn, H. | 登録日 | 2005-07-20 | 公開日 | 2005-12-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Paratope determination of the antithrombotic antibody 82D6A3 based on the crystal structure of its complex with the von Willebrand factor A3-domain J.Biol.Chem., 281, 2006
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4M76
| Integrin I domain of complement receptor 3 in complex with C3d | 分子名称: | Complement C3, Integrin alpha-M, NICKEL (II) ION | 著者 | Bajic, G, Yatime, L, Vorup-Jensen, T, Andersen, G.R. | 登録日 | 2013-08-12 | 公開日 | 2013-10-02 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.804 Å) | 主引用文献 | Structural insight on the recognition of surface-bound opsonins by the integrin I domain of complement receptor 3. Proc.Natl.Acad.Sci.USA, 110, 2013
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3TCX
| Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation | 分子名称: | Integrin alpha-L, Intercellular adhesion molecule 1, MAGNESIUM ION | 著者 | Kang, S, Kim, C.U, Gu, X, Owens, R.M, van Rijn, S.J, Boonyaleepun, V, Mao, Y, Springer, T.A, Jin, M.M. | 登録日 | 2011-08-09 | 公開日 | 2011-08-31 | 最終更新日 | 2014-11-12 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity L Integrin I Domain of Native C-Terminal Helix Conformation To be Published
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3TXA
| Structural Analysis of Adhesive Tip pilin, GBS104 from Group B Streptococcus agalactiae | 分子名称: | CADMIUM ION, Cell wall surface anchor family protein, LITHIUM ION, ... | 著者 | Krishnan, V, Narayana, S.V.L. | 登録日 | 2011-09-23 | 公開日 | 2013-03-27 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.619 Å) | 主引用文献 | Structure of Streptococcus agalactiae tip pilin GBS104: a model for GBS pili assembly and host interactions. Acta Crystallogr.,Sect.D, 69, 2013
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5E6R
| Structures of leukocyte integrin aLb2: The aI domain, the headpiece, and the pocket for the internal ligand | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-L, ... | 著者 | Sen, M, Springer, T.A. | 登録日 | 2015-10-10 | 公開日 | 2016-03-02 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.901 Å) | 主引用文献 | Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops. Proc.Natl.Acad.Sci.USA, 113, 2016
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4NEH
| An internal ligand-bound, metastable state of a leukocyte integrin, aXb2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Sen, M, Yuki, K, Springer, T.A. | 登録日 | 2013-10-29 | 公開日 | 2014-01-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.7505 Å) | 主引用文献 | An internal ligand-bound, metastable state of a leukocyte integrin, alpha X beta 2. J.Cell Biol., 203, 2013
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4NEN
| An internal ligand-bound, metastable state of a leukocyte integrin, aXb2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | 著者 | Sen, M, Yuki, K, Springer, T.A. | 登録日 | 2013-10-29 | 公開日 | 2014-01-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.9012 Å) | 主引用文献 | An internal ligand-bound, metastable state of a leukocyte integrin, alpha X beta 2. J.Cell Biol., 203, 2013
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5E6U
| Structures of leukocyte integrin aLb2: The aI domain, the headpiece, and the pocket for the internal ligand | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | 著者 | Sen, M, Springer, T.A. | 登録日 | 2015-10-10 | 公開日 | 2016-04-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops. Proc.Natl.Acad.Sci.USA, 113, 2016
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5E6S
| Structures of leukocyte integrin aLB2: The aI domain, the headpiece, and the pocket for the internal ligand | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-L, ... | 著者 | Springer, T.A, Sen, M. | 登録日 | 2015-10-10 | 公開日 | 2016-03-02 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops. Proc.Natl.Acad.Sci.USA, 113, 2016
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5ES4
| RE-REFINEMENT OF INTEGRIN ALPHAXBETA2 ECTODOMAIN IN THE CLOSED/BENT CONFORMATION | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Sen, M, Springer, T.A. | 登録日 | 2015-11-16 | 公開日 | 2016-03-02 | 最終更新日 | 2022-03-23 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops. Proc.Natl.Acad.Sci.USA, 113, 2016
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6RHV
| Crystal structure of mouse CD11b I-domain (CD11b-I) in complex with Staphylococcus aureus octameric bi-component leukocidin LukGH (LukH K319A mutant) | 分子名称: | Beta-channel forming cytolysin, DIMETHYL SULFOXIDE, Integrin alpha-M, ... | 著者 | Trstenjak, N, Milic, D, Djinovic-Carugo, K, Badarau, A. | 登録日 | 2019-04-23 | 公開日 | 2019-12-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Molecular mechanism of leukocidin GH-integrin CD11b/CD18 recognition and species specificity. Proc.Natl.Acad.Sci.USA, 117, 2020
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