7MIX

Human N-type voltage-gated calcium channel Cav2.2 in the presence of ziconotide at 3.0 Angstrom resolution

Summary for 7MIX

• Entry DOI: 10.2210/pdb7mix/pdb
• EMDB information: 23867 23868
• Descriptor: Voltage-dependent N-type calcium channel subunit alpha-1B, CHOLESTEROL HEMISUCCINATE, CHOLESTEROL, ... (13 entities in total)
• Functional Keywords: cav2.2, channels, calcium ion-selective, transport protein-toxin complex, drugs, transport protein/toxin
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 453709.62

Authors

Yan, N.,Gao, S.,Yao, X. (deposition date: 2021-04-18, release date: 2021-07-07, Last modification date: 2021-08-18)

• Primary citation: Gao, S.,Yao, X.,Yan, N.; Structure of human Ca v 2.2 channel blocked by the painkiller ziconotide.; Nature, 596:143-147, 2021; PubMed: 34234349; DOI: 10.1038/s41586-021-03699-6

Experimental method

ELECTRON MICROSCOPY (3 Å)