5BV8
G1324S mutation in von Willebrand Factor A1 domain
Summary for 5BV8
| Entry DOI | 10.2210/pdb5bv8/pdb |
| Descriptor | von Willebrand factor, 1,2-ETHANEDIOL, CHLORIDE ION, ... (4 entities in total) |
| Functional Keywords | von willebrand factor, platelet adhesion, vwfa, blood clotting |
| Biological source | Homo sapiens (Human) |
| Cellular location | Secreted : P04275 |
| Total number of polymer chains | 1 |
| Total formula weight | 28306.04 |
| Authors | Campbell, J.C.,Kim, C.,Tischer, A.,Auton, M. (deposition date: 2015-06-04, release date: 2015-12-23, Last modification date: 2023-09-27) |
| Primary citation | Tischer, A.,Campbell, J.C.,Machha, V.R.,Moon-Tasson, L.,Benson, L.M.,Sankaran, B.,Kim, C.,Auton, M. Mutational Constraints on Local Unfolding Inhibit the Rheological Adaptation of von Willebrand Factor. J.Biol.Chem., 291:3848-3859, 2016 Cited by PubMed: 26677223DOI: 10.1074/jbc.M115.703850 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.59 Å) |
Structure validation
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