5BV8
G1324S mutation in von Willebrand Factor A1 domain
Summary for 5BV8
Entry DOI | 10.2210/pdb5bv8/pdb |
Descriptor | von Willebrand factor, 1,2-ETHANEDIOL, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | von willebrand factor, platelet adhesion, vwfa, blood clotting |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted : P04275 |
Total number of polymer chains | 1 |
Total formula weight | 28306.04 |
Authors | Campbell, J.C.,Kim, C.,Tischer, A.,Auton, M. (deposition date: 2015-06-04, release date: 2015-12-23, Last modification date: 2023-09-27) |
Primary citation | Tischer, A.,Campbell, J.C.,Machha, V.R.,Moon-Tasson, L.,Benson, L.M.,Sankaran, B.,Kim, C.,Auton, M. Mutational Constraints on Local Unfolding Inhibit the Rheological Adaptation of von Willebrand Factor. J.Biol.Chem., 291:3848-3859, 2016 Cited by PubMed: 26677223DOI: 10.1074/jbc.M115.703850 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.59 Å) |
Structure validation
Download full validation report