5BV8
G1324S mutation in von Willebrand Factor A1 domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | von Willebrand factor | polymer | 249 | 28208.5 | 1 | UniProt (P04275) Pfam (PF16164) Pfam (PF00092) | Homo sapiens (Human) | vWF |
| 2 | B (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | water | water | 18.0 | 232 | Chemie (HOH) |
Sequence modifications
A: 1238 - 1471 (UniProt: P04275)
| PDB | External Database | Details |
|---|---|---|
| Met 1226 | - | expression tag |
| Arg 1227 | - | expression tag |
| Gly 1228 | - | expression tag |
| Ser 1229 | - | expression tag |
| His 1230 | - | expression tag |
| His 1231 | - | expression tag |
| His 1232 | - | expression tag |
| His 1233 | - | expression tag |
| His 1234 | - | expression tag |
| His 1235 | - | expression tag |
| Gly 1236 | - | expression tag |
| Ser 1237 | - | expression tag |
| Ser 1324 | Gly 1324 | engineered mutation |
| Ala 1381 | Thr 1381 | variant |
| Lys 1472 | - | expression tag |
| Leu 1473 | - | expression tag |
| Asn 1474 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28208.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 97.5 | |
| All* | Total formula weight | 28306.0 |
