7ZWH

VWF Tubules of D1D2 and D'D3A1 domains

Summary for 7ZWH

Entry DOI	10.2210/pdb7zwh/pdb
EMDB information	14998
Descriptor	von Willebrand factor, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	helical, tubule, vwa1, a1 domain, a1, vwf, von willebrand factor, helical tubule, blood clotting
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	312515.35
Authors	Javitt, G.,Fass, D. (deposition date: 2022-05-19, release date: 2022-07-13, Last modification date: 2023-01-11)
Primary citation	Javitt, G.,Yeshaya, N.,Khmelnitsky, L.,Fass, D. Assembly of von Willebrand factor tubules with in vivo helical parameters requires A1 domain insertion. Blood, 140:2835-2843, 2022 Cited by PubMed: 36179246 DOI: 10.1182/blood.2022017153 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation