6JP5

Rabbit Cav1.1-Nifedipine Complex

Summary for 6JP5

EMDB information9866
DescriptorVoltage-dependent L-type calcium channel subunit alpha-1S, Voltage-dependent calcium channel gamma-1 subunit, Voltage-dependent calcium channel subunit alpha-2/delta-1, ... (12 entities in total)
Functional Keywordsmembrane protein complex modulated by fda approved drug., membrane protein
Biological sourceOryctolagus cuniculus (Rabbit)
Total number of polymer chains5
Total molecular weight470871.92
Authors
Zhao, Y.,Huang, G.,Wu, J.,Yan, N. (deposition date: 2019-03-25, release date: 2019-06-12, Last modification date: 2020-07-29)
Primary citation
Zhao, Y.,Huang, G.,Wu, J.,Wu, Q.,Gao, S.,Yan, Z.,Lei, J.,Yan, N.
Molecular Basis for Ligand Modulation of a Mammalian Voltage-Gated Ca2+Channel.
Cell, 177:1495-1506.e12, 2019
PubMed: 31150622 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2019.04.043
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliers28 0.6% 6.4%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload
168889
PDB entries from 2020-09-16