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1U3T
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Crystal Structure of Human Alcohol Dehydrogenase Alpha-Alpha Isoform Complexed with N-Cyclopentyl-N-Cyclobutylformamide Determined to 2.5 Angstrom Resolution
Descriptor: Alcohol dehydrogenase alpha chain, CYCLOBUTYL(CYCLOPENTYL)FORMAMIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Gibbons, B.J, Hurley, T.D.
Deposit date:2004-07-23
Release date:2004-10-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structure of three class I human alcohol dehydrogenases complexed with isoenzyme specific formamide inhibitors
Biochemistry, 43, 2004
1M18
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LIGAND BINDING ALTERS THE STRUCTURE AND DYNAMICS OF NUCLEOSOMAL DNA
Descriptor: Histone H2A.1, Histone H2B.1, Histone H3.2, ...
Authors:Suto, R.K, Edayathumangalam, R.S, White, C.L, Melander, C, Gottesfeld, J.M, Dervan, P.B, Luger, K.
Deposit date:2002-06-18
Release date:2003-02-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands
J.Mol.Biol., 326, 2003
1G47
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1ST LIM DOMAIN OF PINCH PROTEIN
Descriptor: PINCH PROTEIN, ZINC ION
Authors:Velyvis, A, Yang, Y, Wu, C, Qin, J.
Deposit date:2000-10-26
Release date:2001-02-21
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the focal adhesion adaptor PINCH LIM1 domain and characterization of its interaction with the integrin-linked kinase ankyrin repeat domain.
J.Biol.Chem., 276, 2001
1M19
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LIGAND BINDING ALTERS THE STRUCTURE AND DYNAMICS OF NUCLEOSOMAL DNA
Descriptor: 3-AMINO-(DIMETHYLPROPYLAMINE), 4-AMINO-(1-METHYLIMIDAZOLE)-2-CARBOXYLIC ACID, 4-AMINO-(1-METHYLPYRROLE)-2-CARBOXYLIC ACID, ...
Authors:Suto, R.K, Edayathumangalam, R.S, White, C.L, Melander, C, Gottesfeld, J.M, Dervan, P.B, Luger, K.
Deposit date:2002-06-18
Release date:2003-02-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands
J.Mol.Biol., 326, 2003
1LVF
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syntaxin 6
Descriptor: syntaxin 6
Authors:Misura, K.M.S, Bock, J.B, Gonzalez, L.C, Scheller, R.H, Weis, W.I.
Deposit date:2002-05-28
Release date:2002-07-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Three-dimensional structure of the amino-terminal domain of syntaxin 6, a SNAP-25 C homolog.
Proc.Natl.Acad.Sci.USA, 99, 2002
1DRA
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CRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING
Descriptor: CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ...
Authors:Oatley, S.J, Kraut, J.
Deposit date:1991-11-06
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of unliganded Escherichia coli dihydrofolate reductase. Ligand-induced conformational changes and cooperativity in binding.
Biochemistry, 30, 1991
1TVA
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HUMAN DNA POLYMERASE BETA COMPLEXED WITH NICKED DNA CONTAINING A MISMATCHED TEMPLATE THYMIDINE AND INCOMING CYTIDINE
Descriptor: 5'-D(*CP*CP*GP*AP*CP*TP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ...
Authors:Krahn, J.M, Beard, W.A, Wilson, S.H.
Deposit date:2004-06-29
Release date:2004-11-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural insights into DNA polymerase Beta deterrents for misincorporation support an induced-fit mechanism for fidelity
Structure, 12, 2004
1UFG
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Solution structure of immunoglobulin like domain of mouse nuclear lamin
Descriptor: Lamin A
Authors:Kobayashi, N, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-05-29
Release date:2004-06-22
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of immunoglobulin like domain of mouse nuclear lamin
To be Published
1P4R
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Crystal Structure of Human ATIC in complex with folate-based inhibitor BW1540U88UD
Descriptor: AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, Bifunctional purine biosynthesis protein PURH, N-[(S)-(4-{[(2-AMINO-4-HYDROXYQUINAZOLIN-6-YL)(DIHYDROXY)-LAMBDA~4~-SULFANYL]AMINO}PHENYL)(HYDROXY)METHYL]-L-GLUTAMIC ACID, ...
Authors:Cheong, C.-G, Greasley, S.E, Horton, P.A, Beardsley, G.P, Wilson, I.A.
Deposit date:2003-04-23
Release date:2004-03-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates
J.Biol.Chem., 279, 2004
1T2U
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Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1: structure of BRCA1 missense variant V1809F
Descriptor: Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION
Authors:Williams, R.S, Lee, M.S, Duong, D.D, Glover, J.N.M.
Deposit date:2004-04-22
Release date:2004-05-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis of Phosphopeptide recognition by the BRCT domain of BRCA1
Nat.Struct.Mol.Biol., 11, 2004
1DX9
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BU of 1dx9 by Molmil
W57A Apoflavodoxin from Anabaena
Descriptor: Flavodoxin, SULFATE ION
Authors:Romero, A, Sancho, J.
Deposit date:1999-12-23
Release date:2000-04-10
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Dissecting the Energetics of the Apoflavodoxin-Fmn Complex
J.Biol.Chem., 275, 2000
1T3G
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Crystal structure of the Toll/interleukin-1 receptor (TIR) domain of human IL-1RAPL
Descriptor: X-linked interleukin-1 receptor accessory protein-like 1
Authors:Khan, J.A, Tong, L.
Deposit date:2004-04-26
Release date:2005-02-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the Toll/interleukin-1 receptor domain of human IL-1RAPL
J.Biol.Chem., 279, 2004
1OGA
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BU of 1oga by Molmil
A structural basis for immunodominant human T-cell receptor recognition.
Descriptor: BETA-2-MICROGLOBULIN, GILGFVFTL, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Stewart-Jones, G.B.E, McMichael, A.J, Bell, J.I, Stuart, D.I, Jones, E.Y.
Deposit date:2003-04-28
Release date:2003-06-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A Structural Basis for Immunodominant Human T Cell Receptor Recognition
Nat.Immunol., 4, 2003
1E21
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BU of 1e21 by Molmil
Ribonuclease 1 des1-7 Crystal Structure at 1.9A
Descriptor: RIBONUCLEASE 1
Authors:Pous, J, Mallorqui-Fernandez, G, Peracaula, R, Terzyan, S.S, Futami, J, Tada, H, Yamada, H, Seno, M, De Llorens, R, Gomis-Ruth, F.X, Coll, M.
Deposit date:2000-05-15
Release date:2001-05-03
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Three-Dimensional Crystal Structure of Human Rnase 1Dn7 at 1.9A Resolution
Acta Crystallogr.,Sect.D, 57, 2001
1E2W
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N168F mutant of cytochrome f from Chlamydomonas reinhardtii
Descriptor: CYTOCHROME F, HEME C
Authors:Sainz, G, Carrell, C.J, Ponamarev, M.V, Soriano, G.M, Cramer, W.A, Smith, J.L.
Deposit date:2000-05-30
Release date:2000-08-04
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Interruption of the Internal Water Chain of Cytochrome F Impairs Photosynthetic Function
Biochemistry, 39, 2000
1OHH
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BOVINE MITOCHONDRIAL F1-ATPASE complexed with the inhibitor protein IF1
Descriptor: ATP synthase subunit alpha, mitochondrial, ATP synthase subunit beta, ...
Authors:Cabezon, E, Montgomery, M.G, Leslie, A.G.W, Walker, J.E.
Deposit date:2003-05-27
Release date:2003-06-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure of Bovine F1-ATPase in Complex with its Regulatory Protein If1
Nat.Struct.Biol., 10, 2003
1TAZ
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BU of 1taz by Molmil
Catalytic Domain Of Human Phosphodiesterase 1B
Descriptor: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, MAGNESIUM ION, ZINC ION
Authors:Zhang, K.Y.J, Card, G.L, Suzuki, Y, Artis, D.R, Fong, D, Gillette, S, Hsieh, D, Neiman, J, West, B.L, Zhang, C, Milburn, M.V, Kim, S.-H, Schlessinger, J, Bollag, G.
Deposit date:2004-05-19
Release date:2004-08-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:A Glutamine Switch Mechanism for Nucleotide Selectivity by Phosphodiesterases
Mol.Cell, 15, 2004
1OTG
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BU of 1otg by Molmil
5-CARBOXYMETHYL-2-HYDROXYMUCONATE ISOMERASE
Descriptor: 5-CARBOXYMETHYL-2-HYDROXYMUCONATE ISOMERASE, SULFATE ION
Authors:Subramanya, H.S, Roper, D.I, Dauter, Z, Dodson, E.J, Davies, G.J, Wilson, K.S, Wigley, D.B.
Deposit date:1995-11-09
Release date:1996-04-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Enzymatic ketonization of 2-hydroxymuconate: specificity and mechanism investigated by the crystal structures of two isomerases.
Biochemistry, 35, 1996
1OH0
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BU of 1oh0 by Molmil
CRYSTAL STRUCTURE OF KETOSTEROID ISOMERASE COMPLEXED WITH EQUILENIN
Descriptor: BETA-MERCAPTOETHANOL, EQUILENIN, STEROID DELTA-ISOMERASE
Authors:Kim, K.-H, Cha, S.-S, Byun, M, Oh, B.-H.
Deposit date:2003-05-21
Release date:2003-06-04
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:High-Resolution Crystal Structures of Delta5-3-Ketosteroid Isomerase with and without a Reaction Intermediate Analogue
Biochemistry, 36, 1997
1OL5
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BU of 1ol5 by Molmil
Structure of Aurora-A 122-403, phosphorylated on Thr287, Thr288 and bound to TPX2 1-43
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RESTRICTED EXPRESSION PROLIFERATION ASSOCIATED PROTEIN 100, ...
Authors:Bayliss, R, Conti, E.
Deposit date:2003-08-06
Release date:2003-10-30
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis of Aurora-A Activation by Tpx2 at the Mitotic Spindle
Mol.Cell, 12, 2003
1PCE
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BU of 1pce by Molmil
SOLUTION STRUCTURE AND DYNAMICS OF PEC-60, A PROTEIN OF THE KAZAL TYPE INHIBITOR FAMILY, DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Descriptor: PEC-60
Authors:Liepinsh, E, Berndt, K.D, Sillard, R, Mutt, V, Otting, G.
Deposit date:1994-02-22
Release date:1994-04-30
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure and dynamics of PEC-60, a protein of the Kazal type inhibitor family, determined by nuclear magnetic resonance spectroscopy.
J.Mol.Biol., 239, 1994
1T2K
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BU of 1t2k by Molmil
Structure Of The DNA Binding Domains Of IRF3, ATF-2 and Jun Bound To DNA
Descriptor: 31-MER, Cyclic-AMP-dependent transcription factor ATF-2, Interferon regulatory factor 3, ...
Authors:Panne, D, Maniatis, T, Harrison, S.C.
Deposit date:2004-04-21
Release date:2004-11-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-beta enhancer.
Embo J., 23, 2004
1GGL
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BU of 1ggl by Molmil
HUMAN CELLULAR RETINOL BINDING PROTEIN III
Descriptor: PROTEIN (CELLULAR RETINOL-BINDING PROTEIN III)
Authors:Calderone, V, Zanotti, G, Folli, C, Ottonello, S, Bolchi, A, Stoppini, M, Berni, R.
Deposit date:2000-08-23
Release date:2001-03-07
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Identification, retinoid binding, and x-ray analysis of a human retinol-binding protein.
Proc.Natl.Acad.Sci.USA, 98, 2001
1FYJ
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SOLUTION STRUCTURE OF MULTI-FUNCTIONAL PEPTIDE MOTIF-1 PRESENT IN HUMAN GLUTAMYL-PROLYL TRNA SYNTHETASE (EPRS).
Descriptor: MULTIFUNCTIONAL AMINOACYL-TRNA SYNTHETASE
Authors:Jeong, E.-J, Hwang, G.-S, Kim, K.H, Kim, M.J, Kim, S, Kim, K.-S.
Deposit date:2000-10-02
Release date:2001-03-14
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural analysis of multifunctional peptide motifs in human bifunctional tRNA synthetase: identification of RNA-binding residues and functional implications for tandem repeats.
Biochemistry, 39, 2000
1G4Y
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1.60 A CRYSTAL STRUCTURE OF THE GATING DOMAIN FROM SMALL CONDUCTANCE POTASSIUM CHANNEL COMPLEXED WITH CALCIUM-CALMODULIN
Descriptor: CALCIUM ION, CALCIUM-ACTIVATED POTASSIUM CHANNEL RSK2, CALMODULIN, ...
Authors:Schumacher, M.A, Rivard, A, Bachinger, H.P, Adelman, J.P.
Deposit date:2001-01-07
Release date:2001-05-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin.
Nature, 410, 2001

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