7JKB
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![BU of 7jkb by Molmil](/molmil-images/mine/7jkb) | 2xVH Fab | Descriptor: | Anti-Her2, Anti-lysozyme | Authors: | Lord, D.M, Zhou, Y.F. | Deposit date: | 2020-07-28 | Release date: | 2020-11-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Bringing the Heavy Chain to Light: Creating a Symmetric, Bivalent IgG-Like Bispecific. Antibodies, 9, 2020
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7U4P
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1KEM
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1KNO
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2DLF
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![BU of 2dlf by Molmil](/molmil-images/mine/2dlf) | HIGH RESOLUTION CRYSTAL STRUCTURE OF THE FV FRAGMENT FROM AN ANTI-DANSYL SWITCH VARIANT ANTIBODY IGG2A(S) CRYSTALLIZED AT PH 6.75 | Descriptor: | PROTEIN (ANTI-DANSYL IMMUNOGLOBULIN IGG2A(S) (HEAVY CHAIN)), PROTEIN (ANTI-DANSYL IMMUNOGLOBULIN IGG2A(S)-KAPPA (LIGHT CHAIN)), SULFATE ION | Authors: | Nakasako, M, Takahashi, H, Shimada, I, Arata, Y. | Deposit date: | 1998-12-17 | Release date: | 1999-12-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | The pH-dependent structural variation of complementarity-determining region H3 in the crystal structures of the Fv fragment from an anti-dansyl monoclonal antibody. J.Mol.Biol., 291, 1999
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4N8C
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![BU of 4n8c by Molmil](/molmil-images/mine/4n8c) | Three-dimensional structure of the extracellular domain of Matrix protein 2 of influenza A virus | Descriptor: | Extracellular domain of influenza Matrix protein 2, Heavy chain of monoclonal antibody, Light chain of monoclonal antibody | Authors: | Cho, K.J, Seok, J.H, Kim, S, Roose, K, Schepens, B, Fiers, W, Saelens, X, Kim, K.H. | Deposit date: | 2013-10-17 | Release date: | 2014-10-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the extracellular domain of matrix protein 2 of influenza A virus in complex with a protective monoclonal antibody J.Virol., 89, 2015
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1KFA
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![BU of 1kfa by Molmil](/molmil-images/mine/1kfa) | Crystal structure of Fab fragment complexed with gibberellin A4 | Descriptor: | GIBBERELLIN A4, monoclonal antibody heavy chain, monoclonal antibody light chain | Authors: | Murata, T, Fushinobu, S, Nakajima, M, Asami, O, Sassa, T, Wakagi, T, Yamaguchi, I. | Deposit date: | 2001-11-20 | Release date: | 2002-09-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the liganded anti-gibberellin A(4) antibody 4-B8(8)/E9 Fab fragment. Biochem.Biophys.Res.Commun., 293, 2002
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1UM4
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![BU of 1um4 by Molmil](/molmil-images/mine/1um4) | Catalytic Antibody 21H3 with hapten | Descriptor: | (1R)-1-PHENYLETHYL 4-(ACETYLAMINO)BENZYLPHOSPHONATE, Antibody 21H3 H chain, Antibody 21H3 L chain | Authors: | Beuscher IV, A.E, Reuter, J, Olson, A.J, Romesberg, F.E, Schultz, P.G, Wirsching, P, Janda, K.D, Lerner, R.A, Stevens, R.C. | Deposit date: | 2003-09-23 | Release date: | 2004-10-05 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Studies of an Efficient Catalytic Antibody Operating by Ping-Pong and Induced Fit Mechanisms To be Published
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1UJ3
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![BU of 1uj3 by Molmil](/molmil-images/mine/1uj3) | Crystal structure of a humanized Fab fragment of anti-tissue-factor antibody in complex with tissue factor | Descriptor: | IgG Fab heavy chain, IgG Fab light chain, tissue factor | Authors: | Ohto, U, Mizutani, R, Nakamura, M, Adachi, H, Satow, Y. | Deposit date: | 2003-07-25 | Release date: | 2004-07-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of a humanized Fab fragment of anti-tissue-factor antibody in complex with tissue factor. J.Synchrotron Radiat., 11, 2004
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2DQT
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![BU of 2dqt by Molmil](/molmil-images/mine/2dqt) | High resolution crystal structure of the complex of the hydrolytic antibody Fab 6D9 and a transition-state analog | Descriptor: | IMMUNOGLOBULIN 6D9, [1-(3-DIMETHYLAMINO-PROPYL)-3-ETHYL-UREIDO]-[4-(2,2,2-TRIFLUORO-ACETYLAMINO)-BENZYL]PHOSPHINIC ACID-2-(2,2-DIHYDRO-ACETYLAMINO)-3-HYDROXY-1-(4-NITROPHENYL)-PROPYL ESTER | Authors: | Kristensen, O, Vassylyev, D.G, Tanaka, F, Ito, N, Morikawa, K, Fujii, I. | Deposit date: | 2006-05-30 | Release date: | 2006-06-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis J.Mol.Biol., 369, 2007
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2P8M
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![BU of 2p8m by Molmil](/molmil-images/mine/2p8m) | Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide ELLELDKWASLWN in new crystal form | Descriptor: | gp41 peptide, nmAb 2F5, heavy chain, ... | Authors: | Julien, J.P, Bryson, S, Pai, E.F. | Deposit date: | 2007-03-22 | Release date: | 2007-05-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site. J.Mol.Biol., 384, 2008
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2DBL
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2EIZ
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![BU of 2eiz by Molmil](/molmil-images/mine/2eiz) | Crystal structure of humanized HYHEL-10 fv mutant(HW47Y)-hen lysozyme complex | Descriptor: | ANTI-LYSOZYME ANTIBODY FV REGION, Lysozyme C | Authors: | Nakanishi, T, Tsumoto, K, Yokota, A, Kondo, H, Kumagai, I. | Deposit date: | 2007-03-14 | Release date: | 2008-03-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Critical contribution of VH-VL interaction to reshaping of an antibody: the case of humanization of anti-lysozyme antibody, HyHEL-10 Protein Sci., 17, 2008
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2DTM
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![BU of 2dtm by Molmil](/molmil-images/mine/2dtm) | Thermodynamic and structural analyses of hydrolytic mechanism by catalytic antibodies | Descriptor: | IMMUNOGLOBULIN 6D9 | Authors: | Oda, M, Ito, N, Tsumuraya, T, Suzuki, K, Fujii, I. | Deposit date: | 2006-07-13 | Release date: | 2007-05-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis J.Mol.Biol., 369, 2007
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2DD8
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![BU of 2dd8 by Molmil](/molmil-images/mine/2dd8) | Crystal Structure of SARS-CoV Spike Receptor-Binding Domain Complexed with Neutralizing Antibody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IGG Heavy Chain, IGG Light Chain, ... | Authors: | Prabakaran, P, Gan, J.H, Feng, Y, Zhu, Z.Y, Xiao, X.D, Ji, X, Dimitrov, D.S. | Deposit date: | 2006-01-24 | Release date: | 2006-04-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of Severe Acute Respiratory Syndrome Coronavirus Receptor-binding Domain Complexed with Neutralizing Antibody J.Biol.Chem., 281, 2006
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5X08
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![BU of 5x08 by Molmil](/molmil-images/mine/5x08) | Crystal structure of broadly neutralizing anti-HIV-1 antibody 4E10, mutant Npro, with peptide bound | Descriptor: | ACETATE ION, CHLORIDE ION, Envelope glycoprotein gp160, ... | Authors: | Caaveiro, J.M.M, Rujas, E, Nieva, J.L, Tsumoto, K. | Deposit date: | 2017-01-20 | Release date: | 2017-04-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Functional Contacts between MPER and the Anti-HIV-1 Broadly Neutralizing Antibody 4E10 Extend into the Core of the Membrane J. Mol. Biol., 429, 2017
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5AZE
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![BU of 5aze by Molmil](/molmil-images/mine/5aze) | Fab fragment of calcium-dependent antigen binding antibody, 6RL#9 | Descriptor: | 6RL#9 FAB HEAVY CHAIN, 6RL#9 FAB LIGHT CHAIN, CALCIUM ION | Authors: | Kadono, S, Hironiwa, N, Ishii, S, Igawa, T, Hattori, K. | Deposit date: | 2015-10-02 | Release date: | 2015-11-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Calcium-dependent antigen binding as a novel modality for antibody recycling by endosomal antigen dissociation Mabs, 8, 2016
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5XKU
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![BU of 5xku by Molmil](/molmil-images/mine/5xku) | Crystal structure of hemagglutinin globular head from an H7N9 influenza virus in complex with a neutralizing antibody HNIgGA6 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HNIgGA6 heavy chain, HNIgGA6 light chain, ... | Authors: | Chen, C, Wang, J, Wang, W, Gao, X, Cui, S, Jin, Q. | Deposit date: | 2017-05-09 | Release date: | 2017-11-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structural Insight into a Human Neutralizing Antibody against Influenza Virus H7N9 J. Virol., 92, 2018
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4N0Y
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4N1H
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![BU of 4n1h by Molmil](/molmil-images/mine/4n1h) | Structure of a single-domain camelid antibody fragment cAb-F11N in complex with the BlaP beta-lactamase from Bacillus licheniformis | Descriptor: | Beta-lactamase, Camelid heavy-chain antibody variable fragment cAb-F11N | Authors: | Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M. | Deposit date: | 2013-10-04 | Release date: | 2014-10-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments To be Published
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5B6F
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![BU of 5b6f by Molmil](/molmil-images/mine/5b6f) | Crystal structure of the Fab fragment of an anti-Leukotriene C4 monoclonal antibody complexed with LTC4 | Descriptor: | (5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-[[(4~{S})-4-azanyl-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]-3-(2-hydroxy-2-oxoethylamino)-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, ... | Authors: | Sugahara, M, Ago, H, Saino, H, Miyano, M. | Deposit date: | 2016-05-27 | Release date: | 2017-05-31 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the Fab fragment of an anti-Leukotriene C4 monoclonal antibody complexed with LTC4 To Be Published
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5I17
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![BU of 5i17 by Molmil](/molmil-images/mine/5i17) | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV1-69/IGKV3-20 | Descriptor: | FAB HEAVY CHAIN, FAB LIGHT CHAIN, SULFATE ION | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | Deposit date: | 2016-02-05 | Release date: | 2016-06-08 | Last modified: | 2016-08-03 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural diversity in a human antibody germline library. Mabs, 8, 2016
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5I8H
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![BU of 5i8h by Molmil](/molmil-images/mine/5i8h) | Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer in Complex with V3 Loop-targeting Antibody PGT122 Fab and Fusion Peptide-targeting Antibody VRC34.01 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.664 gp120, ... | Authors: | Xu, K, Zhou, T, Kwong, P.D. | Deposit date: | 2016-02-18 | Release date: | 2016-05-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (4.301 Å) | Cite: | Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody. Science, 352, 2016
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5I1D
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![BU of 5i1d by Molmil](/molmil-images/mine/5i1d) | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-23/IGKV4-1 | Descriptor: | FAB HEAVY CHAIN, FAB LIGHT CHAIN, SULFATE ION | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | Deposit date: | 2016-02-05 | Release date: | 2016-02-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural diversity in a human antibody germline library. Mabs, 8, 2016
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5BMF
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![BU of 5bmf by Molmil](/molmil-images/mine/5bmf) | Crystal Structure of a Theophylline binding antibody Fab fragment | Descriptor: | 2-(5-{1-[1-(1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-4,15-dioxo-8,11-dioxa-5,14-diazaicosan-20-yl]-3,3-dimethyl-6-sulfo-1,3-dihydro-2H-indol-2-ylidene}penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indolium-5-sulfonate, Fab fragment heavy chain, Fab fragment light chain | Authors: | Bujotzek, A, Fuchs, A, Changtao, Q, Klostermann, S, Benz, J, Antes, I, Dengl, S, Hoffmann, E, Georges, G. | Deposit date: | 2015-05-22 | Release date: | 2015-07-29 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | MoFvAb: Modeling the Fv region of antibodies. Mabs, 7, 2015
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