7SXQ
| Plasmodium falciparum apicoplast DNA polymerase (exo-minus) without affinity tag | Descriptor: | 1,2-ETHANEDIOL, Apicoplast DNA polymerase, CHLORIDE ION, ... | Authors: | Nieto, N, Chheda, P, Kerns, R, Nelson, S, Honzatko, R. | Deposit date: | 2021-11-24 | Release date: | 2022-10-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Promising antimalarials targeting apicoplast DNA polymerase from Plasmodium falciparum. Eur.J.Med.Chem., 243, 2022
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2ENI
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2EII
| Crystal analysis of delta1-pyrroline-5-carboxylate dehydrogenase from Thermus thermophilus with bound L-valine and NAD. | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1-pyrroline-5-carboxylate dehydrogenase, ACETATE ION, ... | Authors: | Inagaki, E, Sakamoto, K, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-13 | Release date: | 2007-09-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Crystal structure analysis of delta1-pyrroline-5-carboxylate dehydrogenase in ternary complex with inhibitor and NAD. To be Published
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8Q6K
| Human IgD Fab in complex with an orthosteric inhibitor of Phl p 7 | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Human IgD Fab heavy chain, ... | Authors: | Davies, A.M, Vester, S.K, McDonnell, J.M. | Deposit date: | 2023-08-11 | Release date: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Expanding the Anti-Phl p 7 Antibody Toolkit: An Anti-Idiotype Nanobody Inhibitor. Antibodies, 12, 2023
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2EJJ
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7TDS
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2BDG
| Human Kallikrein 4 complex with nickel and p-aminobenzamidine | Descriptor: | CHLORIDE ION, Kallikrein-4, NICKEL (II) ION, ... | Authors: | Debela, M, Bode, W, Goettig, P, Structural Proteomics in Europe (SPINE) | Deposit date: | 2005-10-20 | Release date: | 2006-10-03 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structures of human tissue kallikrein 4: activity modulation by a specific zinc binding site. J.Mol.Biol., 362, 2006
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7TIN
| The Structure of S. aureus MenD | Descriptor: | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, CALCIUM ION, CHLORIDE ION, ... | Authors: | Johnston, J.M, Stanborough, T, Ho, N.A.T, Akazong, E.W, Jiao, W. | Deposit date: | 2022-01-14 | Release date: | 2022-09-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Allosteric inhibition of Staphylococcus aureus MenD by 1,4-dihydroxy naphthoic acid: a feedback inhibition mechanism of the menaquinone biosynthesis pathway. Philos.Trans.R.Soc.Lond.B Biol.Sci., 378, 2023
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8Q6S
| A carbohydrate esterase family 15 (CE15) glucuronoyl esterase from Phocaeicola vulgatus ATCC 8482 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, Putative acetyl xylan esterase, ... | Authors: | Mazurkewich, S, Seveso, A, Banerjee, S, Lo Leggio, L, Larsbrink, J. | Deposit date: | 2023-08-14 | Release date: | 2023-12-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Polysaccharide utilization loci from Bacteroidota encode CE15 enzymes with possible roles in cleaving pectin-lignin bonds. Appl.Environ.Microbiol., 90, 2024
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8G0I
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3MK1
| Refinement of placental alkaline phosphatase complexed with nitrophenyl | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Alkaline phosphatase, ... | Authors: | Stec, B, Cheltsov, A, Millan, J.L. | Deposit date: | 2010-04-13 | Release date: | 2011-01-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Refined structures of placental alkaline phosphatase show a consistent pattern of interactions at the peripheral site. Acta Crystallogr.,Sect.F, 66, 2010
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8Q00
| TssM-Ub-PA complex - A USP-like DUB from B. pseudomallei (193-430) reacted with Ub-PA | Descriptor: | 1,2-ETHANEDIOL, CITRATE ANION, Polyubiquitin-B, ... | Authors: | Uthoff, M, Hermanns, T, Hofmann, K, Baumann, U. | Deposit date: | 2023-07-27 | Release date: | 2023-12-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | The structural basis for deubiquitination by the fingerless USP-type effector TssM. Life Sci Alliance, 7, 2024
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8POF
| The crystal structure of RsSymEG1 reveals a unique form of smaller GH7 endoglucanases alongside GH7 cellobiohydrolases in protist symbionts of termites | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Putative glycosyl hydrolase family7, SODIUM ION | Authors: | Haataja, T, Sandgren, M, Hansson, H, Stahlberg, J. | Deposit date: | 2023-07-04 | Release date: | 2023-12-27 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The crystal structure of RsSymEG1 reveals a unique form of smaller GH7 endoglucanases alongside GH7 cellobiohydrolases in protist symbionts of termites. Febs J., 291, 2024
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8FYV
| Salmonella enterica serovar Typhimurium chemoreceptor Tsr (taxis to serine and repellents) ligand-binding domain in complex with l-serine | Descriptor: | CHLORIDE ION, Methyl-accepting chemotaxis protein, SERINE, ... | Authors: | Baylink, A, Gentry-Lear, Z, Glenn, S. | Deposit date: | 2023-01-26 | Release date: | 2024-05-15 | Last modified: | 2024-06-12 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Bacterial vampirism mediated through taxis to serum. Elife, 12, 2024
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3MNJ
| Human Carbonic Anhydrase II Mutant K170E | Descriptor: | Carbonic anhydrase 2, SODIUM ION, ZINC ION | Authors: | Domsic, J.F, McKenna, R. | Deposit date: | 2010-04-21 | Release date: | 2010-07-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural and kinetic study of the extended active site for proton transfer in human carbonic anhydrase II. Biochemistry, 49, 2010
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8PS0
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8Q1S
| Pathogenic mutations of human phosphorylation sites affect protein-protein interactions | Descriptor: | 1,2-ETHANEDIOL, 14-3-3 protein epsilon, BROMIDE ION, ... | Authors: | Roske, Y, Daumke, O, Rrustemi, T, Selbach, M. | Deposit date: | 2023-08-01 | Release date: | 2024-02-21 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (3.23 Å) | Cite: | Pathogenic mutations of human phosphorylation sites affect protein-protein interactions. Nat Commun, 15, 2024
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8FHA
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3MP8
| Crystal structure of Sgf29 tudor domain | Descriptor: | 4-(HYDROXYMETHYL)BENZAMIDINE, ACETIC ACID, GLYCEROL, ... | Authors: | Li, J, Wu, M, Ruan, J, Zang, J. | Deposit date: | 2010-04-26 | Release date: | 2011-05-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation Embo J., 30, 2011
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8PXV
| Targeting extended blood antigens by Akkermansia muciniphila enzymes unveils a missing link for generating universal donor blood | Descriptor: | Beta-N-acetylhexosaminidase, GLYCEROL, SODIUM ION, ... | Authors: | Weikum, J, Jensen, M, Abou Hachem, M, Morth, J.P. | Deposit date: | 2023-07-24 | Release date: | 2024-02-28 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Akkermansia muciniphila exoglycosidases target extended blood group antigens to generate ABO-universal blood. Nat Microbiol, 9, 2024
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8PVS
| Targeting extended blood antigens by Akkermansia muciniphila enzymes unveils a missing link for generating universal donor blood | Descriptor: | 1,2-ETHANEDIOL, Alpha-1,3-galactosidase B, CALCIUM ION, ... | Authors: | Jensen, M, Abou Hachem, M, Morth, J.P. | Deposit date: | 2023-07-18 | Release date: | 2024-02-28 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Akkermansia muciniphila exoglycosidases target extended blood group antigens to generate ABO-universal blood. Nat Microbiol, 9, 2024
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8PXT
| Targeting extended blood antigens by Akkermansia muciniphila enzymes unveils a missing link for generating universal donor blood | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose, Beta-N-acetylhexosaminidase, CHLORIDE ION, ... | Authors: | Jensen, M, Abou Hachem, M, Morth, J.P. | Deposit date: | 2023-07-24 | Release date: | 2024-02-28 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Akkermansia muciniphila exoglycosidases target extended blood group antigens to generate ABO-universal blood. Nat Microbiol, 9, 2024
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2BFG
| crystal structure of beta-xylosidase (fam GH39) in complex with dinitrophenyl-beta-xyloside and covalently bound xyloside | Descriptor: | 2,5-DINITROPHENOL, BETA-XYLOSIDASE, SODIUM ION, ... | Authors: | Czjzek, M, Bravman, T, Henrissat, B, Shoham, Y. | Deposit date: | 2004-12-07 | Release date: | 2005-10-12 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Enzyme-Substrate Complex Structures of a Gh39 Beta-Xylosidase from Geobacillus Stearothermophilus. J.Mol.Biol., 353, 2005
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8PHA
| O(S)-methyltransferase from Pleurotus sapidus | Descriptor: | 2-HYDROXY BUTANE-1,4-DIOL, GLYCEROL, L-ornithine, ... | Authors: | Korf, L, Essen, L.-O. | Deposit date: | 2023-06-19 | Release date: | 2024-03-27 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | A Novel O - and S -Methyltransferase from Pleurotus sapidus Is Involved in Flavor Formation. J.Agric.Food Chem., 72, 2024
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7UFK
| Crystal structure of chimeric omicron RBD (strain BA.2) complexed with human ACE2 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhang, W, Shi, K, Geng, Q, Ye, G, Aihara, H, Li, F. | Deposit date: | 2022-03-22 | Release date: | 2022-10-19 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Structural basis for mouse receptor recognition by SARS-CoV-2 omicron variant. Proc.Natl.Acad.Sci.USA, 119, 2022
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