8PXT

Targeting extended blood antigens by Akkermansia muciniphila enzymes unveils a missing link for generating universal donor blood

Summary for 8PXT

• Entry DOI: 10.2210/pdb8pxt/pdb
• Descriptor: Beta-N-acetylhexosaminidase, 2-acetamido-2-deoxy-beta-D-galactopyranose, SODIUM ION, ... (5 entities in total)
• Functional Keywords: beta-hexosaminidase, akkermansia muciniphila, galnac-b converting, cbm, hydrolase
• Biological source: Akkermansia muciniphila
• Total number of polymer chains: 3
• Total formula weight: 221428.80

Authors

Jensen, M.,Abou Hachem, M.,Morth, J.P. (deposition date: 2023-07-24, release date: 2024-02-28, Last modification date: 2024-03-06)

• Primary citation: Jensen, M.,Stenfelt, L.,Hagman, J.R.,Pichler, M.J.,Weikum, J.,Nielsen, T.S.,Hult, A.,Morth, J.P.,Olsson, M.L.,Abou Hachem, M.; Akkermansia muciniphila exoglycosidases target extended blood group antigens to generate ABO-universal blood; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.25 Å)