8PXT
Targeting extended blood antigens by Akkermansia muciniphila enzymes unveils a missing link for generating universal donor blood
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Beta-N-acetylhexosaminidase | polymer | 655 | 73251.0 | 3 | UniProt (B2UN02) Pfam (PF02838) Pfam (PF00728) | Akkermansia muciniphila | |
| 2 | D, E, F, I, J... (A, B, C) | 2-acetamido-2-deoxy-beta-D-galactopyranose | non-polymer | 221.2 | 7 | Chemie (NGA) | |||
| 3 | G, H, M, N (A, C) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 4 | O (C) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | P, Q, R (A, B, C) | water | water | 18.0 | 521 | Chemie (HOH) |
Sequence modifications
A, B, C: 2 - 647 (UniProt: B2UN02)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Ala 321 | Glu 339 | conflict |
| Leu 648 | - | expression tag |
| Glu 649 | - | expression tag |
| His 650 | - | expression tag |
| His 651 | - | expression tag |
| His 652 | - | expression tag |
| His 653 | - | expression tag |
| His 654 | - | expression tag |
| His 655 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 219752.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1675.9 | |
| All* | Total formula weight | 221428.8 |
