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5V7L
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BU of 5v7l by Molmil
PCNA mutant R61A/D63A Protein Defective in Gene Silencing
Descriptor: Proliferating cell nuclear antigen
Authors:Kondratick, C.M, Litman, J.M, Washington, M.T, Dieckman, L.M.
Deposit date:2017-03-20
Release date:2018-03-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.201 Å)
Cite:Crystal structures of PCNA mutant proteins defective in gene silencing suggest a novel interaction site on the front face of the PCNA ring.
PLoS ONE, 13, 2018
5UJ7
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BU of 5uj7 by Molmil
Structure of the active form of human Origin Recognition Complex ATPase motor module, complex subunitS 1, 4, 5
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ...
Authors:Tocilj, A, Elkayam, E, On, K.F, Joshua-Tor, L.
Deposit date:2017-01-17
Release date:2017-02-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.394 Å)
Cite:Structure of the active form of human Origin Recognition Complex and its ATPase motor module.
Elife, 6, 2017
7L5F
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BU of 7l5f by Molmil
Crystal Structure of N-(2-oxocyclobutyl) decanamide Bound AiiA-Co
Descriptor: 4-(decanoylamino)butanoic acid, COBALT (II) ION, GLYCEROL, ...
Authors:Mascarenhas, R.N, Liu, D.
Deposit date:2020-12-22
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Cyclobutanone Inhibitor of Cobalt-Functionalized Metallo-gamma-Lactonase AiiA with Cyclobutanone Ring Opening in the Active Site.
Acs Omega, 6, 2021
5VF3
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BU of 5vf3 by Molmil
Bacteriophage T4 isometric capsid
Descriptor: Capsid vertex protein gp24, Highly immunogenic outer capsid protein, Major capsid protein, ...
Authors:Chen, Z, Sun, L, Zhang, Z, Fokine, A, Padilla-Sanchez, V, Hanein, D, Jiang, W, Rossmann, M.G, Rao, V.B.
Deposit date:2017-04-06
Release date:2017-09-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of the bacteriophage T4 isometric head at 3.3- angstrom resolution and its relevance to the assembly of icosahedral viruses.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4EXP
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BU of 4exp by Molmil
Structure of mouse Interleukin-34 in complex with mouse FMS
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-34, Macrophage colony-stimulating factor 1 receptor
Authors:Liu, H, Leo, C, Chen, X, Wong, B.R, Williams, L.T, Lin, H, He, X.
Deposit date:2012-04-30
Release date:2012-05-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1.
Biochim.Biophys.Acta, 1824, 2012
4ETU
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BU of 4etu by Molmil
Crystal structure of rabbit ryanodine receptor 1 mutant R2939S
Descriptor: GLYCEROL, Ryanodine receptor 1
Authors:Yuchi, Z, Lau, K, Van Petegem, F.
Deposit date:2012-04-24
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Disease mutations in the ryanodine receptor central region: crystal structures of a phosphorylation hot spot domain.
Structure, 20, 2012
4ERT
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BU of 4ert by Molmil
Crystal structure of rabbit ryanodine receptor 1 (2734-2940)
Descriptor: GLYCEROL, POTASSIUM ION, Ryanodine receptor 1
Authors:Yuchi, Z, Lau, K, Van Petegem, F.
Deposit date:2012-04-20
Release date:2012-06-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Disease mutations in the ryanodine receptor central region: crystal structures of a phosphorylation hot spot domain.
Structure, 20, 2012
4ESU
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BU of 4esu by Molmil
Crystal structure of rabbit ryanodine receptor 1 mutant S2776M
Descriptor: GLYCEROL, Ryanodine receptor 1
Authors:Yuchi, Z, Lau, K, Van Petegem, F.
Deposit date:2012-04-23
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Disease mutations in the ryanodine receptor central region: crystal structures of a phosphorylation hot spot domain.
Structure, 20, 2012
4ERV
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BU of 4erv by Molmil
Crystal structure of human ryanodine receptor 3 (2597-2800)
Descriptor: GLYCEROL, Ryanodine receptor 3, SULFATE ION
Authors:Yuchi, Z, Lau, K, Van Petegem, F.
Deposit date:2012-04-20
Release date:2012-06-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Disease mutations in the ryanodine receptor central region: crystal structures of a phosphorylation hot spot domain.
Structure, 20, 2012
4E0X
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BU of 4e0x by Molmil
Crystal structure of the kainate receptor GluK1 ligand-binding domain in complex with kainate in the absence of glycerol
Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CHLORIDE ION, Glutamate receptor, ...
Authors:Frydenvang, K, Kastrup, J.S.
Deposit date:2012-03-05
Release date:2012-04-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Kainate induces various domain closures in AMPA and kainate receptors.
Neurochem Int, 61, 2012
4E0W
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BU of 4e0w by Molmil
Crystal structure of the kainate receptor GluK3 ligand binding domain in complex with kainate
Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CHLORIDE ION, Glutamate receptor, ...
Authors:Venskutonyte, R, Frydenvang, K, Kastrup, J.S.
Deposit date:2012-03-05
Release date:2012-05-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3501 Å)
Cite:Kainate induces various domain closures in AMPA and kainate receptors.
Neurochem Int, 61, 2012
4ETT
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BU of 4ett by Molmil
Crystal structure of rabbit ryanodine receptor 1 mutant E2764K
Descriptor: GLYCEROL, Ryanodine receptor 1
Authors:Yuchi, Z, Lau, K, Van Petegem, F.
Deposit date:2012-04-24
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.195 Å)
Cite:Disease mutations in the ryanodine receptor central region: crystal structures of a phosphorylation hot spot domain.
Structure, 20, 2012
7O0N
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BU of 7o0n by Molmil
Crystal structure of a ParB E93A mutant from Myxococcus xanthus bound to CDP and monothiophosphate
Descriptor: CYTIDINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Altegoer, F, Bange, G.
Deposit date:2021-03-26
Release date:2021-09-15
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:The CTPase activity of ParB determines the size and dynamics of prokaryotic DNA partition complexes.
Mol.Cell, 81, 2021
4ETV
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BU of 4etv by Molmil
Crystal structure of mouse ryanodine receptor 2 (2699-2904)
Descriptor: CHLORIDE ION, Ryanodine receptor 2
Authors:Yuchi, Z, Lau, K, Van Petegem, F.
Deposit date:2012-04-24
Release date:2012-06-13
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Disease mutations in the ryanodine receptor central region: crystal structures of a phosphorylation hot spot domain.
Structure, 20, 2012
4EXN
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BU of 4exn by Molmil
Crystal structure of mouse Interleukin-34
Descriptor: Interleukin-34, alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Liu, H, Leo, C, Chen, X, Wong, B.R, Williams, L.T, Lin, H, He, X.
Deposit date:2012-04-30
Release date:2012-05-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1.
Biochim.Biophys.Acta, 1824, 2012
7C2M
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BU of 7c2m by Molmil
Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with NITD-349
Descriptor: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Chimera of drug exporters of the RND superfamily-like protein and Endolysin, N-(4,4-dimethylcyclohexyl)-4,6-bis(fluoranyl)-1H-indole-2-carboxamide, ...
Authors:Zhang, B, Yang, X, Hu, T, Rao, Z.
Deposit date:2020-05-08
Release date:2020-12-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis for the Inhibition of Mycobacterial MmpL3 by NITD-349 and SPIRO.
J.Mol.Biol., 432, 2020
5WTB
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BU of 5wtb by Molmil
Complex Structure of Staphylococcus aureus SdrE with human complement factor H
Descriptor: Peptide from Complement factor H, Serine-aspartate repeat-containing protein E
Authors:Wu, M, Zhang, Y, Hang, T, Wang, C, Yang, Y, Zang, J, Zhang, M, Zhang, X.
Deposit date:2016-12-10
Release date:2017-07-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion
Biochem. J., 474, 2017
5WCE
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BU of 5wce by Molmil
Caulobacter crescentus pol III beta
Descriptor: DNA polymerase III subunit beta
Authors:Oakley, A.J.
Deposit date:2017-06-30
Release date:2017-07-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of Pol III beta from Caulobacter crescentus
To Be Published
5X06
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BU of 5x06 by Molmil
DNA replication regulation protein
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase III subunit beta, DnaA regulatory inactivator Hda, ...
Authors:Kim, J, Cho, Y.
Deposit date:2017-01-20
Release date:2018-01-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.237 Å)
Cite:Replication regulation protein
To Be Published
5YD0
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BU of 5yd0 by Molmil
Crystal structure of Schlafen 13 (SLFN13) N'-domain
Descriptor: Schlafen 8, ZINC ION
Authors:Yang, J.-Y, Gao, S.
Deposit date:2017-09-09
Release date:2018-03-28
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.182 Å)
Cite:Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control
Nat Commun, 9, 2018
5Y6J
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BU of 5y6j by Molmil
Structure of Tomato spotted wilt virus nucleocapsid protein with alternative oligomerization state
Descriptor: Nucleoprotein
Authors:Guo, Y, Dong, S, Lou, Z.
Deposit date:2017-08-12
Release date:2017-09-27
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.811 Å)
Cite:Distinct Mechanism for the Formation of the Ribonucleoprotein Complex of Tomato Spotted Wilt Virus.
J. Virol., 91, 2017
7EP8
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BU of 7ep8 by Molmil
Crystal structure of PCNA from Neurospora crassa
Descriptor: Proliferating cell nuclear antigen
Authors:Sundaram, R, Vasudevan, D.
Deposit date:2021-04-26
Release date:2021-06-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Interdomain connecting loop and J loop structures determine cross-species compatibility of PCNA.
J.Biol.Chem., 297, 2021
7BGG
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BU of 7bgg by Molmil
Crystal structure of the heterocyclic toxin methyltransferase from Mycobacterium tuberculosis
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, SODIUM ION, heterocyclic toxin methyltransferase (Rv0560c)
Authors:Denkhaus, L, Sartor, P, Einsle, O, Gerhardt, S, Fetzner, S.
Deposit date:2021-01-07
Release date:2021-09-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:Structural basis of O-methylation of (2-heptyl-)1-hydroxyquinolin-4(1H)-one and related compounds by the heterocyclic toxin methyltransferase Rv0560c of Mycobacterium tuberculosis.
J.Struct.Biol., 213, 2021
7C2N
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BU of 7c2n by Molmil
Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with SPIRO
Descriptor: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 1'-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)spiro[6,7-dihydrothieno[3,2-c]pyran-4,4'-piperidine], Drug exporters of the RND superfamily-like protein,Endolysin, ...
Authors:Zhang, B, Yang, X, Hu, T, Rao, Z.
Deposit date:2020-05-08
Release date:2020-12-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Structural Basis for the Inhibition of Mycobacterial MmpL3 by NITD-349 and SPIRO.
J.Mol.Biol., 432, 2020
6TLT
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BU of 6tlt by Molmil
ROR(gamma)t ligand binding domain in complex with desmosterol and allosteric ligand Glenmark
Descriptor: 4-[1-[2,6-bis(chloranyl)phenyl]carbonyl-5-methyl-thieno[3,2-c]pyrazol-3-yl]benzoic acid, GLYCEROL, Nuclear receptor ROR-gamma, ...
Authors:de Vries, R.M.J.M, Meijer, F.A, Brunsveld, L.
Deposit date:2019-12-03
Release date:2020-12-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Cooperativity between the orthosteric and allosteric ligand binding sites of ROR gamma t.
Proc.Natl.Acad.Sci.USA, 118, 2021

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