8SQU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8squ by Molmil](/molmil-images/mine/8squ) | Monomeric MapSPARTA bound with guide RNA and target DNA hybrid | Descriptor: | MAGNESIUM ION, TIR-APAZ, guide RNA, ... | Authors: | Shen, Z.F, Yang, X.Y, Fu, T.M. | Deposit date: | 2023-05-04 | Release date: | 2023-08-23 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Oligomerization-mediated activation of a short prokaryotic Argonaute. Nature, 621, 2023
|
|
4U0Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4u0y by Molmil](/molmil-images/mine/4u0y) | |
4UZC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4uzc by Molmil](/molmil-images/mine/4uzc) | |
7CUI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cui by Molmil](/molmil-images/mine/7cui) | Crystal structure of fission yeast Pot1 and Tpz1 | Descriptor: | Protection of telomeres protein 1, Protection of telomeres protein tpz1, SULFATE ION | Authors: | Sun, H, Wu, Z, Wu, J, Lei, M. | Deposit date: | 2020-08-23 | Release date: | 2021-08-25 | Last modified: | 2022-09-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insights into Pot1-ssDNA, Pot1-Tpz1 and Tpz1-Ccq1 Interactions within fission yeast shelterin complex. Plos Genet., 18, 2022
|
|
8SOK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sok by Molmil](/molmil-images/mine/8sok) | |
8SV6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sv6 by Molmil](/molmil-images/mine/8sv6) | Structure of the M. smegmatis DarR protein | Descriptor: | Fatty acid metabolism regulator protein | Authors: | Schumacher, M.A. | Deposit date: | 2023-05-15 | Release date: | 2023-11-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.56 Å) | Cite: | Structures of the DarR transcription regulator reveal unique modes of second messenger and DNA binding. Nat Commun, 14, 2023
|
|
7CQ2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cq2 by Molmil](/molmil-images/mine/7cq2) | Crystal structure of Slx1-Slx4 | Descriptor: | GLYCEROL, SLX4 isoform 1, Structure-specific endonuclease subunit SLX1, ... | Authors: | Xu, X, Wang, M, Sun, J, Li, G, Yang, N, Xu, R.M. | Deposit date: | 2020-08-08 | Release date: | 2021-06-16 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure specific DNA recognition by the SLX1-SLX4 endonuclease complex. Nucleic Acids Res., 49, 2021
|
|
7CQ3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cq3 by Molmil](/molmil-images/mine/7cq3) | Crystal structure of Slx1-Slx4 | Descriptor: | SLX4 isoform 1, SULFATE ION, Structure-specific endonuclease subunit SLX1, ... | Authors: | Xu, X, Wang, M, Sun, J, Li, G, Yang, N, Xu, R.M. | Deposit date: | 2020-08-08 | Release date: | 2021-06-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.449 Å) | Cite: | Structure specific DNA recognition by the SLX1-SLX4 endonuclease complex. Nucleic Acids Res., 49, 2021
|
|
7DEP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7dep by Molmil](/molmil-images/mine/7dep) | S. aureus SsbB with 5-FU | Descriptor: | 5-FLUOROURACIL, Single-stranded DNA-binding protein | Authors: | Lin, E.S, Huang, Y.H, Huang, C.Y. | Deposit date: | 2020-11-04 | Release date: | 2020-12-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.094 Å) | Cite: | Crystal structure of the single-stranded DNA-binding protein SsbB in complex with the anticancer drug 5-fluorouracil: Extension of the 5-fluorouracil interactome to include the oligonucleotide/oligosaccharide-binding fold protein Biochem.Biophys.Res.Commun., 534, 2020
|
|
7D8J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7d8j by Molmil](/molmil-images/mine/7d8j) | S. aureus SsbB with 5-FU | Descriptor: | 5-FLUOROURACIL, Single-stranded DNA-binding protein | Authors: | Lin, E.S, Huang, Y.H, Huang, C.Y. | Deposit date: | 2020-10-08 | Release date: | 2020-12-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Crystal structure of the single-stranded DNA-binding protein SsbB in complex with the anticancer drug 5-fluorouracil: Extension of the 5-fluorouracil interactome to include the oligonucleotide/oligosaccharide-binding fold protein Biochem.Biophys.Res.Commun., 534, 2020
|
|
6DEG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6deg by Molmil](/molmil-images/mine/6deg) | |
4O68
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o68 by Molmil](/molmil-images/mine/4o68) | Structure of human cyclic GMP-AMP synthase (cGAS) | Descriptor: | Cyclic GMP-AMP synthase, ZINC ION | Authors: | Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J. | Deposit date: | 2013-12-20 | Release date: | 2014-02-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.436 Å) | Cite: | The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop. Cell Rep, 6, 2014
|
|
4O67
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o67 by Molmil](/molmil-images/mine/4o67) | Human cyclic GMP-AMP synthase (cGAS) in complex with GAMP | Descriptor: | Cyclic GMP-AMP synthase, ZINC ION, cGAMP | Authors: | Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J. | Deposit date: | 2013-12-20 | Release date: | 2014-02-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.444 Å) | Cite: | The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop. Cell Rep, 6, 2014
|
|
4O69
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o69 by Molmil](/molmil-images/mine/4o69) | Human cyclic GMP-AMP synthase (cGAS) in complex with sulfate ion | Descriptor: | Cyclic GMP-AMP synthase, SULFATE ION, ZINC ION | Authors: | Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J. | Deposit date: | 2013-12-20 | Release date: | 2014-02-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.252 Å) | Cite: | The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop. Cell Rep, 6, 2014
|
|
3U05
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3u05 by Molmil](/molmil-images/mine/3u05) | Crystal structure of DB1804-D(CGCGAATTCGCG)2 complex | Descriptor: | 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', 6-(1,4,5,6-tetrahydropyrimidin-2-yl)-2-[4'-(1,4,5,6-tetrahydropyrimidin-2-yl)biphenyl-4-yl]-1H-indole, MAGNESIUM ION | Authors: | Wei, D.G, Neidle, S. | Deposit date: | 2011-09-28 | Release date: | 2012-09-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.27 Å) | Cite: | Small-molecule binding to the DNA minor groove is mediated by a conserved water cluster. J.Am.Chem.Soc., 135, 2013
|
|
4OFA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ofa by Molmil](/molmil-images/mine/4ofa) | |
8SP3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sp3 by Molmil](/molmil-images/mine/8sp3) | Asymmetric dimer of MapSPARTA bound with gRNA/tDNA hybrid | Descriptor: | MAGNESIUM ION, TIR-APAZ, guide RNA, ... | Authors: | Shen, Z.F, Yang, X.Y, Fu, T.M. | Deposit date: | 2023-05-01 | Release date: | 2023-08-23 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Oligomerization-mediated activation of a short prokaryotic Argonaute. Nature, 621, 2023
|
|
8SP0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sp0 by Molmil](/molmil-images/mine/8sp0) | Symmetric dimer of MapSPARTA bound with gRNA/tDNA hybrid | Descriptor: | MAGNESIUM ION, TIR-APAZ, guide RNA, ... | Authors: | Shen, Z.F, Yang, X.Y, Fu, T.M. | Deposit date: | 2023-05-01 | Release date: | 2023-08-23 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Oligomerization-mediated activation of a short prokaryotic Argonaute. Nature, 621, 2023
|
|
6D47
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6d47 by Molmil](/molmil-images/mine/6d47) | |
3KU0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ku0 by Molmil](/molmil-images/mine/3ku0) | Structure of GAP31 with adenine at its binding pocket | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENINE, Ribosome-inactivating protein gelonin | Authors: | Kong, X.-P. | Deposit date: | 2009-11-26 | Release date: | 2010-01-26 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A new activity of anti-HIV and anti-tumor protein GAP31: DNA adenosine glycosidase--structural and modeling insight into its functions. Biochem.Biophys.Res.Commun., 391, 2010
|
|
3KO2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ko2 by Molmil](/molmil-images/mine/3ko2) | I-MsoI re-designed for altered DNA cleavage specificity (-7C) | Descriptor: | 5'-D(*CP*GP*GP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*GP*TP*CP*TP*GP*C)-3', 5'-D(*GP*CP*AP*GP*AP*CP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*CP*CP*G)-3', CALCIUM ION, ... | Authors: | Taylor, G.K, Stoddard, B.L. | Deposit date: | 2009-11-13 | Release date: | 2010-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs. Nucleic Acids Res., 38, 2010
|
|
7CUJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cuj by Molmil](/molmil-images/mine/7cuj) | Crystal structure of fission yeast Ccq1 and Tpz1 | Descriptor: | Coiled-coil quantitatively-enriched protein 1, Protection of telomeres protein tpz1 | Authors: | Sun, H, Wu, Z, Wu, J, Lei, M. | Deposit date: | 2020-08-23 | Release date: | 2021-08-25 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into Pot1-ssDNA, Pot1-Tpz1 and Tpz1-Ccq1 Interactions within fission yeast shelterin complex. Plos Genet., 18, 2022
|
|
4FHC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4fhc by Molmil](/molmil-images/mine/4fhc) | Spore photoproduct lyase | Descriptor: | 1,2-ETHANEDIOL, IRON/SULFUR CLUSTER, SULFATE ION, ... | Authors: | Benjdia, A, Heil, K, Barends, T.R.M, Carell, T, Schlichting, I. | Deposit date: | 2012-06-06 | Release date: | 2012-07-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzyme. Nucleic Acids Res., 40, 2012
|
|
7COW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cow by Molmil](/molmil-images/mine/7cow) | 353 bp di-nucleosome harboring cohesive DNA termini with linker histone H1.0 | Descriptor: | CALCIUM ION, CHLORIDE ION, DNA (353-MER), ... | Authors: | Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A. | Deposit date: | 2020-08-05 | Release date: | 2021-08-11 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Engineering nucleosomes for generating diverse chromatin assemblies. Nucleic Acids Res., 49, 2021
|
|
2GAJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gaj by Molmil](/molmil-images/mine/2gaj) | |