3KO2
I-MsoI re-designed for altered DNA cleavage specificity (-7C)
Summary for 3KO2
Entry DOI | 10.2210/pdb3ko2/pdb |
Descriptor | Site-specific DNA endonuclease I-MsoI, 5'-D(*GP*CP*AP*GP*AP*CP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*CP*CP*G)-3', 5'-D(*CP*GP*GP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*GP*TP*CP*TP*GP*C)-3', ... (5 entities in total) |
Functional Keywords | redesign, protein-dna complex, chloroplast, endonuclease, hydrolase-dna complex, hydrolase/dna |
Biological source | Monomastix sp. More |
Total number of polymer chains | 8 |
Total formula weight | 108131.54 |
Authors | Taylor, G.K.,Stoddard, B.L. (deposition date: 2009-11-13, release date: 2010-05-19, Last modification date: 2023-09-06) |
Primary citation | Ashworth, J.,Taylor, G.K.,Havranek, J.J.,Quadri, S.A.,Stoddard, B.L.,Baker, D. Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs. Nucleic Acids Res., 38:5601-5608, 2010 Cited by PubMed: 20435674DOI: 10.1093/nar/gkq283 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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