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3CJ0
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Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with small molecule fragments
Descriptor: 4-[(5-bromopyridin-2-yl)amino]-4-oxobutanoic acid, RNA-directed RNA polymerase
Authors:Kissinger, c.
Deposit date:2008-03-12
Release date:2008-04-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
4JPZ
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BU of 4jpz by Molmil
Voltage-gated sodium channel 1.2 C-terminal domain in complex with FGF13U and Ca2+/calmodulin
Descriptor: CALCIUM ION, Calmodulin, Fibroblast growth factor 13, ...
Authors:Wang, C, Chung, B.C, Yan, H, Wang, H.G, Lee, S.Y, Pitt, G.S.
Deposit date:2013-03-19
Release date:2014-04-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Structural analyses of Ca(2+)/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation.
Nat Commun, 5, 2014
2EWE
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BU of 2ewe by Molmil
Crystal structure of Pectate Lyase C R218K mutant in complex with pentagalacturonic acid
Descriptor: CALCIUM ION, Pectate lyase C, alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid
Authors:Scavetta, R.D, Jurnak, F.
Deposit date:2005-11-02
Release date:2005-11-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a Plant Cell Wall Fragment Complexed to Pectate Lyase C
Plant Cell, 11, 1999
4I31
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Crystal structure of HCV NS3/NS4A protease complexed with compound 4
Descriptor: (2R,6S,7E,10E,13aR,14aR,16aS)-2-{[7-methoxy-8-methyl-2-(propan-2-yloxy)quinolin-4-yl]oxy}-N-[(1-methylcyclopropyl)sulfonyl]-6-{[(1-methyl-1H-pyrazol-3-yl)carbonyl]amino}-5,16-dioxo-1,2,3,6,9,12,13,13a,14,15,16,16a-dodecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a(5H)-carboxamide, Genome polyprotein, HCV non-structural protein 4A, ...
Authors:Lemke, C.T.
Deposit date:2012-11-23
Release date:2013-01-02
Last modified:2013-03-13
Method:X-RAY DIFFRACTION (1.9301 Å)
Cite:Molecular Mechanism by Which a Potent Hepatitis C Virus NS3-NS4A Protease Inhibitor Overcomes Emergence of Resistance.
J.Biol.Chem., 288, 2013
3CJ3
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BU of 3cj3 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
Descriptor: 4-bromo-2-{[(2R)-2-(2-chlorobenzyl)pyrrolidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
Authors:Kissinger, c.
Deposit date:2008-03-12
Release date:2008-04-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3U27
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BU of 3u27 by Molmil
Crystal structure of ethanolamine utilization protein EutL from Leptotrichia buccalis C-1013-b
Descriptor: CALCIUM ION, GLYCEROL, Microcompartments protein, ...
Authors:Wu, R, Gu, M, Kerfeld, C.A, Salmeen, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2011-10-01
Release date:2012-02-08
Last modified:2020-01-29
Method:X-RAY DIFFRACTION (1.852 Å)
Cite:Crystal structure of ethanolamine utilization protein EutL from Leptotrichia buccalis C-1013-b
To be Published
2EDN
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BU of 2edn by Molmil
Solution structure of the first ig-like domain from human Myosin-binding protein C, fast-type
Descriptor: Myosin-binding protein C, fast-type
Authors:Nagashima, K, Kurosaki, C, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-14
Release date:2007-08-14
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the first ig-like domain from human Myosin-binding protein C, fast-type
To be Published
3GV4
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BU of 3gv4 by Molmil
Crystal structure of human HDAC6 zinc finger domain and ubiquitin C-terminal peptide RLRGG
Descriptor: CALCIUM ION, Histone deacetylase 6, ZINC ION, ...
Authors:Dong, A, Ravichandran, M, Loppnau, P, Li, Y, MacKenzie, F, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Dhe-Paganon, S, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
Deposit date:2009-03-30
Release date:2009-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Crystal structure of human HDAC6 zinc finger domain and ubiquitin C-terminal peptide RLRGG
To be Published
1QC7
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T. MARITIMA FLIG C-TERMINAL DOMAIN
Descriptor: PROTEIN (FLIG)
Authors:Lloyd, S.A, Whitby, F.G, Blair, D, Hill, C.P.
Deposit date:1999-05-18
Release date:1999-08-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the C-terminal domain of FliG, a component of the rotor in the bacterial flagellar motor
Nature, 400, 1999
1CSY
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SYK TYROSINE KINASE C-TERMINAL SH2 DOMAIN COMPLEXED WITH A PHOSPHOPEPTIDEFROM THE GAMMA CHAIN OF THE HIGH AFFINITY IMMUNOGLOBIN G RECEPTOR, NMR
Descriptor: ACETYL-THR-PTR-GLU-THR-LEU-NH2, SYK PROTEIN TYROSINE KINASE
Authors:Narula, S.S, Yuan, R.W, Adams, S.E, Green, O.M, Green, J, Phillips, T.B, Zydowsky, L.D, Botfield, M.C, Hatada, M.H, Laird, E.R, Zoller, M.J, Karas, J.L, Dalgarno, D.C.
Deposit date:1995-10-03
Release date:1996-11-08
Last modified:2024-06-05
Method:SOLUTION NMR
Cite:Solution structure of the C-terminal SH2 domain of the human tyrosine kinase Syk complexed with a phosphotyrosine pentapeptide.
Structure, 3, 1995
1I2T
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BU of 1i2t by Molmil
X-RAY STRUCTURE OF THE HUMAN HYPERPLASTIC DISCS PROTEIN: AN ORTHOLOG OF THE C-TERMINAL DOMAIN OF POLY(A)-BINDING PROTEIN
Descriptor: HYD PROTEIN
Authors:Deo, R.C, Sonenberg, N, Burley, S.K.
Deposit date:2001-02-12
Release date:2001-04-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:X-ray structure of the human hyperplastic discs protein: an ortholog of the C-terminal domain of poly(A)-binding protein.
Proc.Natl.Acad.Sci.USA, 98, 2001
2IUM
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BU of 2ium by Molmil
Structure of the C-terminal head domain of the avian adenovirus CELO long fibre (C2 crystal form)
Descriptor: AVIAN ADENOVIRUS CELO LONG FIBRE
Authors:Guardado-Calvo, P, Llamas-Saiz, A.L, Fox, G.C, van Raaij, M.J.
Deposit date:2006-06-06
Release date:2007-06-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the C-terminal head domain of the fowl adenovirus type 1 long fiber.
J. Gen. Virol., 88, 2007
3PVB
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BU of 3pvb by Molmil
Crystal structure of (73-244)RIa:C holoenzyme of cAMP-dependent Protein kinase
Descriptor: GLYCEROL, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Boettcher, A.J, Wu, J, Kim, C, Yang, J, Bruystens, J, Cheung, N, Pennypacker, J.K, Blumenthal, D.A, Kornev, A.P, Taylor, S.S.
Deposit date:2010-12-06
Release date:2011-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structure of (73-244)RIa:C holoenzyme of cAMP-dependent Protein kinase
Structure, 19, 2011
2GIW
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BU of 2giw by Molmil
SOLUTION STRUCTURE OF REDUCED HORSE HEART CYTOCHROME C, NMR, 40 STRUCTURES
Descriptor: CYTOCHROME C, HEME C
Authors:Banci, L, Bertini, I, Huber, J.G, Spyroulias, G.A, Turano, P.
Deposit date:1998-06-25
Release date:1998-12-09
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of reduced horse heart cytochrome c.
J.Biol.Inorg.Chem., 4, 1999
3SS5
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BU of 3ss5 by Molmil
Crystal structure of mouse Glutaminase C, L-glutamate-bound form
Descriptor: GLUTAMIC ACID, Glutaminase C
Authors:Ambrosio, A.L.B, Dias, S.M.G, Cerione, R.A.
Deposit date:2011-07-07
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
2K2J
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BU of 2k2j by Molmil
NMR solution structure of the split PH domain from Phospholipase C gamma 2
Descriptor: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2
Authors:Harris, R, Bunney, T.D, Katan, M, Driscoll, P.C.
Deposit date:2008-04-02
Release date:2008-09-09
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Rac Regulates Its Effector Phospholipase C{gamma}2 through Interaction with a Split Pleckstrin Homology Domain.
J.Biol.Chem., 283, 2008
2IIH
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BU of 2iih by Molmil
Crystal structure of the molybdenum cofactor biosynthesis protein C (TTHA1789) from thermus theromophilus HB8 (H32 form)
Descriptor: Molybdenum cofactor biosynthesis protein C, PHOSPHATE ION
Authors:Jeyakanthan, J, Kanaujia, S.P, Vasuki Ranjani, C, Sekar, K, Baba, S, Chen, L, Liu, Z.-J, Wang, B.-C, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-09-28
Release date:2007-10-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of the molybdenum cofactor biosynthesis protein C (TTHA1789) from thermus theromophilus HB8 (H32 form)
To be Published
1PL5
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BU of 1pl5 by Molmil
Crystal Structure Analysis of the Sir4p C-terminal Coiled Coil
Descriptor: Regulatory protein SIR4
Authors:Murphy, G.A, Spedale, E.J, Powell, S.T, Pillus, L, Schultz, S.C, Chen, L.
Deposit date:2003-06-06
Release date:2004-06-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Sir4 C-terminal coiled coil is required for telomeric and mating type silencing in Saccharomyces cerevisiae.
J.Mol.Biol., 334, 2003
1XOY
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BU of 1xoy by Molmil
Solution structure of At3g04780.1, an Arabidopsis ortholog of the C-terminal domain of human thioredoxin-like protein
Descriptor: hypothetical protein At3g04780.1
Authors:Song, J, Robert, C.T, Lee, M.S, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2004-10-07
Release date:2004-10-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of At3g04780.1-des15, an Arabidopsis thaliana ortholog of the C-terminal domain of human thioredoxin-like protein.
Protein Sci., 14, 2005
3SS4
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BU of 3ss4 by Molmil
Crystal structure of mouse Glutaminase C, phosphate-bound form
Descriptor: Glutaminase C, PHOSPHATE ION
Authors:Ambrosio, A.L.B, Dias, S.M.G, Cerione, R.A.
Deposit date:2011-07-07
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3G66
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BU of 3g66 by Molmil
The crystal structure of Streptococcus pneumoniae Sortase C provides novel insights into catalysis as well as pilin substrate specificity
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Sortase C
Authors:Neiers, F, Madhurantakam, C, Falker, S, Manzano, C, Dessen, A, Normark, S, Henriques-Normark, B, Achour, A.
Deposit date:2009-02-06
Release date:2009-09-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Two crystal structures of pneumococcal pilus sortase C provide novel insights into catalysis and substrate specificity.
J.Mol.Biol., 393, 2009
3G6G
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Equally potent inhibition of c-Src and Abl by compounds that recognize inactive kinase conformations
Descriptor: GLYCEROL, N-{3-[(3-{4-[(4-methoxyphenyl)amino]-1,3,5-triazin-2-yl}pyridin-2-yl)amino]-4-methylphenyl}-4-[(4-methylpiperazin-1-yl)methyl]benzamide, Proto-oncogene tyrosine-protein kinase Src
Authors:Seeliger, M.A, Ranjitkar, P, Kasap, C, Shan, Y, Shaw, D.E, Shah, N.P, Kuriyan, J, Maly, D.J.
Deposit date:2009-02-06
Release date:2009-03-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Equally potent inhibition of c-Src and Abl by compounds that recognize inactive kinase conformations
Cancer Res., 69, 2009
2CE0
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BU of 2ce0 by Molmil
Structure of oxidized Arabidopsis thaliana cytochrome 6A
Descriptor: CYTOCHROME C6, HEME C
Authors:Marcaida, M.J, Schlarb-Ridley, B.G, Worrall, J.A.R, Wastl, J, Evans, T.J, Bendall, D.S, Luisi, B.F, Howe, C.J.
Deposit date:2006-02-01
Release date:2006-07-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Structure of Cytochrome C(6A), a Novel Dithio-Cytochrome of Arabidopsis Thaliana, and its Reactivity with Plastocyanin: Implications for Function.
J.Mol.Biol., 360, 2006
2CE1
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Structure of reduced Arabidopsis thaliana cytochrome 6A
Descriptor: CYTOCHROME C6, HEME C
Authors:Marcaida, M.J, Schlarb-Ridley, B.G, Worrall, J.A.R, Wastl, J, Evans, T.J, Bendall, D.S, Luisi, B.F, Howe, C.J.
Deposit date:2006-02-02
Release date:2006-07-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of Cytochrome C(6A), a Novel Dithio-Cytochrome of Arabidopsis Thaliana, and its Reactivity with Plastocyanin: Implications for Function.
J.Mol.Biol., 360, 2006
3PYF
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BU of 3pyf by Molmil
Mycobacterium tuberculosis 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) in complex with AMP-PNP
Descriptor: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Shan, S, Chen, X.H, Liu, T, Zhao, H.C, Rao, Z.H, Lou, Z.Y.
Deposit date:2010-12-13
Release date:2012-01-25
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Structural Basis for anti-TB Drug Discovery targeting of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) from Mycobacterium tuberculosis
To be Published

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