4I4K

Streptomyces globisporus C-1027 9-membered enediyne conserved protein SgcE6

Summary for 4I4K

• Entry DOI: 10.2210/pdb4i4k/pdb
• Related: 4OVM
• Descriptor: uncharacterized protein SgcJ, CITRIC ACID, TETRAETHYLENE GLYCOL, ... (7 entities in total)
• Functional Keywords: structural genomics, psi-biology, midwest center for structural genomics, mcsg, enzyme discovery for natural product biosynthesis, natpro, alpha-beta sandwich, unknown function
• Biological source: Streptomyces globisporus
• Total number of polymer chains: 2
• Total formula weight: 31040.28

Authors

Kim, Y.,Bigelow, L.,Clancy, S.,Babnigg, J.,Bingman, C.A.,Yennamalli, R.,Lohman, J.R.,Ma, M.,Shen, B.,Phillips Jr., G.N.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG),Enzyme Discovery for Natural Product Biosynthesis (NatPro) (deposition date: 2012-11-27, release date: 2012-12-12, Last modification date: 2016-12-07)

• Primary citation: Huang, T.,Chang, C.Y.,Lohman, J.R.,Rudolf, J.D.,Kim, Y.,Chang, C.,Yang, D.,Ma, M.,Yan, X.,Crnovcic, I.,Bigelow, L.,Clancy, S.,Bingman, C.A.,Yennamalli, R.M.,Babnigg, G.,Joachimiak, A.,Phillips, G.N.,Shen, B.; Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027.; J Antibiot (Tokyo), 69:731-740, 2016; PubMed: 27406907; DOI: 10.1038/ja.2016.88

Experimental method

X-RAY DIFFRACTION (1.7 Å)