PDB: 435 件ウェブページステータス検索Chemie searchBIRD

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6Z7Z	Porcine insulin in complex with the analytical antibody OXI-005 Fab 分子名称: Insulin, MAGNESIUM ION, OXI-005 Fab Heavy chain, ... 著者 Johansson, E. 登録日 2020-06-02 公開日 2020-12-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Insulin binding to the analytical antibody sandwich pair OXI-005 and HUI-018: Epitope mapping and binding properties. Protein Sci., 30, 2021
6Z7W	Human insulin in complex with the analytical antibody HUI-018 Fab 分子名称: HUI-018 Fab Heavy Chain, Insulin, MAb 6H10 light chain 著者 Johansson, E. 登録日 2020-06-02 公開日 2020-12-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Insulin binding to the analytical antibody sandwich pair OXI-005 and HUI-018: Epitope mapping and binding properties. Protein Sci., 30, 2021
6GV0	Insulin glulisine 分子名称: FORMIC ACID, Insulin, ZINC ION 著者 Chayen, N.E, Helliwell, J.R, Solomon-Gamsu, H.V, Govada, L, Morgan, M, Gillis, R.B, Adams, G. 登録日 2018-06-20 公開日 2019-07-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 Analysis of insulin glulisine at the molecular level by X-ray crystallography and biophysical techniques. Sci Rep, 11, 2021
6ZHB	3D electron diffraction structure of bovine insulin 分子名称: Insulin, ZINC ION 著者 Blum, T, Housset, D, Clabbers, M.T.B, van Genderen, E, Bacia-Verloop, M, Zander, U, McCarthy, A.A, Schoehn, G, Ling, W.L, Abrahams, J.P. 登録日 2020-06-22 公開日 2021-01-27 最終更新日 2024-01-24 実験手法 ELECTRON CRYSTALLOGRAPHY (3.25 Å) 主引用文献 Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals. Acta Crystallogr D Struct Biol, 77, 2021
6ZI8	X-ray diffraction structure of bovine insulin at 2.3 A resolution 分子名称: CHLORIDE ION, Insulin, ZINC ION 著者 Housset, D, Ling, W.L, Bacia-Verloop, M, Zander, U, McCarthy, A.A, Schoehn, G. 登録日 2020-06-25 公開日 2021-01-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals. Acta Crystallogr D Struct Biol, 77, 2021
6H3M	The crystal structure of a human seleno-insulin analog 分子名称: Insulin 著者 Lansky, S, Weil-Ktorza, O, Metanis, N, Shoham, G. 登録日 2018-07-19 公開日 2019-08-14 最終更新日 2020-08-26 実験手法 X-RAY DIFFRACTION (1.821 Å) 主引用文献 Substitution of an Internal Disulfide Bridge with a Diselenide Enhances both Foldability and Stability of Human Insulin. Chemistry, 25, 2019
8ONK	Human insulin in complex with the analytical antibody S1 Fab and the analytical antibody HUI-001 Fab 分子名称: Heavy chain of analytical antibody HUI-001 Fab, Heavy chain of analytical antibody S1 Fab, Insulin A chain, ... 著者 Johansson, E. 登録日 2023-04-03 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (3.403 Å) 主引用文献 Macromolecular structure of insulin and IgE clonality impacts IgE-mediated activation of sensitized basophils To Be Published
8ONI	Human insulin in complex with the analytical antibody S1 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of analytical antibody S1 Fab, Insulin A chain, ... 著者 Johansson, E. 登録日 2023-04-03 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Macromolecular structure of insulin and IgE clonality impacts IgE-mediated activation of sensitized basophils To Be Published
8PI5	Crystal structure of human insulin desB30 precursor with an Alanine-Methionine-Lysine C-peptide in hexamer (T3R3) conformation 分子名称: CHLORIDE ION, Insulin B chain,Insulin A chain, RESORCINOL, ... 著者 Johansson, E, Schluckebier, G. 登録日 2023-06-21 公開日 2023-11-08 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
7AC4	Structure of insulin collected by rotation serial crystallography on a COC membrane at a synchrotron source 分子名称: Insulin, R-1,2-PROPANEDIOL, SODIUM ION 著者 Martiel, I, Padeste, C, Karpik, A, Huang, C.Y, Vera, L, Wang, M, Marsh, M. 登録日 2020-09-09 公開日 2021-09-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Versatile microporous polymer-based supports for serial macromolecular crystallography. Acta Crystallogr D Struct Biol, 77, 2021
8PI6	Crystal structure of the monomeric zinc free human insulin A22K, B3E, B26E, B29R, desB30 precursor with a Ser-Glu-Asp-Trp-Trp-Arg C-peptide and a Glu-Glu-Gly-Glu-Pro-Arg N-terminal extension 分子名称: Insulin B chain,Insulin A chain 著者 Johansson, E, Schluckebier, G. 登録日 2023-06-21 公開日 2023-11-08 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
8PJC	Crystal structure of human insulin desB30 precursor with an Alanine-Alanine-Lysine C-peptide in dimer (T2) conformation 分子名称: Insulin 著者 Schluckebier, G, Johansson, E. 登録日 2023-06-23 公開日 2023-11-08 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
8PJH	Crystal structure of human insulin desB30 precursor with an Aspartate-Glycine-Lysine C-peptide in dimer (T2) conformation 分子名称: Insulin 著者 Schluckebier, G, Johansson, E. 登録日 2023-06-23 公開日 2023-11-08 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
8PI4	Crystal structure of human insulin desB30 precursor with an Alanine-Methionine-Lysine C-peptide in dimer (T2) conformation 分子名称: Insulin B chain,Insulin A chain 著者 Johansson, E, Schluckebier, G. 登録日 2023-06-21 公開日 2023-11-08 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
8SBD	Cryo-EM structure of insulin amyloid-like fibril that is composed of two antiparallel protofilaments 分子名称: Insulin A chain, Insulin B chain 著者 Wang, L.W, Hall, C, Uchikawa, E, Chen, D.L, Choi, E, Zhang, X.W, Bai, X.C. 登録日 2023-04-03 公開日 2023-08-30 最終更新日 2023-09-27 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural basis of insulin fibrillation. Sci Adv, 9, 2023
6INS	X-RAY ANALYSIS OF THE SINGLE CHAIN B29-A1 PEPTIDE-LINKED INSULIN MOLECULE. A COMPLETELY INACTIVE ANALOGUE 分子名称: INSULIN, ZINC ION 著者 Derewenda, U, Derewenda, Z, Dodson, E.J, Dodson, G.G, Bing, X, Markussen, J. 登録日 1992-11-25 公開日 1994-01-31 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray analysis of the single chain B29-A1 peptide-linked insulin molecule. A completely inactive analogue. J.Mol.Biol., 220, 1991
6JR3	Crystal structure of insulin hexamer fitted into cryo EM density map where each dimer was kept as rigid body 分子名称: Insulin A chain, Insulin B chain 著者 Sengupta, J, Pathak, B.K, Bhakta, S. 登録日 2019-04-02 公開日 2020-04-22 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (14.5 Å) 主引用文献 Resveratrol as a nontoxic excipient stabilizes insulin in a bioactive hexameric form. J.Comput.Aided Mol.Des., 34, 2020
6K59	Structure of Glargine insulin in 20% acetic acid-d4 (pH 1.9) 分子名称: Glargine Insulin Chain-A, Glargine insulin Chain-B 著者 Ratha, B.N, Kar, R.K, Bhunia, A. 登録日 2019-05-28 公開日 2020-05-06 実験手法 SOLUTION NMR 主引用文献 Molecular Details of a Salt Bridge and Its Role in Insulin Fibrillation by NMR and Raman Spectroscopic Analysis. J.Phys.Chem.B, 124, 2020
6OR0	Crystal structure of Insulin from Non-merohedrally twinned crystals 分子名称: Insulin chain A, Insulin chain B 著者 Sevvana, M, Ruf, M, Uson, I, Sheldrick, G.M, Herbst-Irmer, R. 登録日 2019-04-29 公開日 2019-12-11 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Non-merohedral twinning: from minerals to proteins. Acta Crystallogr D Struct Biol, 75, 2019
6S34	Zinc free, dimeric human insulin determined to 1.35 Angstrom resolution 分子名称: 1,2-ETHANEDIOL, Insulin A chain, Insulin B chain 著者 Johansson, E. 登録日 2019-06-24 公開日 2019-07-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Zinc free, dimeric human insulin determined to 1.35 Angstrom resolution Not Published
6S4J	Crystal structure of zinc free A14E, B25H, B29K(N(eps)-[2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]), desB27, desB30 human insulin 分子名称: IMIDAZOLE, Insulin, KUT [2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl] 著者 Johansson, E. 登録日 2019-06-28 公開日 2020-07-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Molecular engineering of safe and efficacious oral basal insulin. Nat Commun, 11, 2020
6S4I	Crystal structure of zinc free A14E, B25H, B29K(N(eps)-[2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]), desB30 human insulin 分子名称: Insulin, NITRATE ION 著者 Johansson, E. 登録日 2019-06-28 公開日 2020-07-15 最終更新日 2020-08-12 実験手法 X-RAY DIFFRACTION (1.511 Å) 主引用文献 Molecular engineering of safe and efficacious oral basal insulin. Nat Commun, 11, 2020
6RVA	STRUCTURE OF [ASP58]-IGF-I ANALOGUE 分子名称: Insulin-like growth factor I 著者 Jiracek, J, Zakova, L, Socha, O. 登録日 2019-05-31 公開日 2019-10-02 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Mutations at hypothetical binding site 2 in insulin and insulin-like growth factors 1 and 2 result in receptor- and hormone-specific responses. J.Biol.Chem., 294, 2019
6P4Z	Structure of gadolinium-caged cobalt (III) insulin hexamer 分子名称: CHLORIDE ION, COBALT (II) ION, GADOLINIUM ATOM, ... 著者 Tran, T.H, Taylor, S.K, Stojanovic, M.N, Tong, L. 登録日 2019-05-29 公開日 2019-06-12 最終更新日 2019-12-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Insulin Hexamer-Caged Gadolinium Ion as MRI Contrast-o-phore ChemBioChem, 24, 2018
6TC2	Monoclinic human insulin in complex with p-coumaric acid 分子名称: 4'-HYDROXYCINNAMIC ACID, Insulin, PHOSPHATE ION, ... 著者 Triandafillidis, D.-P, Parthenios, N, Spiliopoulou, M, Valmas, A, Kosinas, C, Gozzo, F, Reinle-Schmitt, M, Beckers, D, Degen, T, Pop, M, Fitch, A, Wollenhaupt, J, Weiss, M.S, Karavassili, F, Margiolaki, I. 登録日 2019-11-04 公開日 2020-11-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Insulin polymorphism induced by two polyphenols: new crystal forms and advances in macromolecular powder diffraction. Acta Crystallogr D Struct Biol, 76, 2020

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