6TC2

Monoclinic human insulin in complex with p-coumaric acid

Summary for 6TC2

Entry DOI	10.2210/pdb6tc2/pdb
Descriptor	Insulin, ZINC ION, PHOSPHATE ION, ... (6 entities in total)
Functional Keywords	human insulin, p-coumaric acid, hexamer, complex, hormone
Biological source	Homo sapiens (Human)
Total number of polymer chains	12
Total formula weight	145172.95
Authors	Triandafillidis, D.-P.,Parthenios, N.,Spiliopoulou, M.,Valmas, A.,Kosinas, C.,Gozzo, F.,Reinle-Schmitt, M.,Beckers, D.,Degen, T.,Pop, M.,Fitch, A.,Wollenhaupt, J.,Weiss, M.S.,Karavassili, F.,Margiolaki, I. (deposition date: 2019-11-04, release date: 2020-11-11, Last modification date: 2024-01-24)
Primary citation	Triandafillidis, D.P.,Parthenios, N.,Spiliopoulou, M.,Valmas, A.,Kosinas, C.,Gozzo, F.,Reinle-Schmitt, M.,Beckers, D.,Degen, T.,Pop, M.,Fitch, A.N.,Wollenhaupt, J.,Weiss, M.S.,Karavassili, F.,Margiolaki, I. Insulin polymorphism induced by two polyphenols: new crystal forms and advances in macromolecular powder diffraction. Acta Crystallogr D Struct Biol, 76:1065-1079, 2020 Cited by PubMed: 33135678 DOI: 10.1107/S205979832001195X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.36 Å)

Structure validation