6TC2

Monoclinic human insulin in complex with p-coumaric acid

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005179	molecular_function	hormone activity
A	0005576	cellular_component	extracellular region
B	0005179	molecular_function	hormone activity
B	0005576	cellular_component	extracellular region
C	0005179	molecular_function	hormone activity
C	0005576	cellular_component	extracellular region
D	0005179	molecular_function	hormone activity
D	0005576	cellular_component	extracellular region
E	0005179	molecular_function	hormone activity
E	0005576	cellular_component	extracellular region
F	0005179	molecular_function	hormone activity
F	0005576	cellular_component	extracellular region
G	0005179	molecular_function	hormone activity
G	0005576	cellular_component	extracellular region
H	0005179	molecular_function	hormone activity
H	0005576	cellular_component	extracellular region
I	0005179	molecular_function	hormone activity
I	0005576	cellular_component	extracellular region
J	0005179	molecular_function	hormone activity
J	0005576	cellular_component	extracellular region
K	0005179	molecular_function	hormone activity
K	0005576	cellular_component	extracellular region
L	0005179	molecular_function	hormone activity
L	0005576	cellular_component	extracellular region

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN B 101

Chain	Residue
B	HIS10
B	PO4102
F	HIS10
J	HIS10

---

site_id	AC2
Number of Residues	7
Details	binding site for residue PO4 B 102

Chain	Residue
F	HIS10
J	HIS10
B	HIS10
B	ZN101
B	HOH201
B	HOH203
B	HOH208

---

site_id	AC3
Number of Residues	9
Details	binding site for residue HC4 C 101

Chain	Residue
C	CYS6
C	SER9
C	CYS11
C	HOH201
C	HOH202
D	HIS10
J	GLU13
L	HIS5
L	SER9

---

site_id	AC4
Number of Residues	5
Details	binding site for residue SCN D 101

Chain	Residue
D	HIS10
D	HC4102
D	ZN103
H	HIS10
L	HIS10

---

site_id	AC5
Number of Residues	16
Details	binding site for residue HC4 D 102

Chain	Residue
D	ASN3
D	LEU6
D	HIS10
D	SCN101
D	ZN103
E	GLY1
E	GLU4
H	ASN3
H	LEU6
H	HIS10
L	PHE1
L	VAL2
L	ASN3
L	LEU6
L	HIS10
L	PO4101

---

site_id	AC6
Number of Residues	5
Details	binding site for residue ZN D 103

Chain	Residue
D	HIS10
D	SCN101
D	HC4102
H	HIS10
L	HIS10

---

site_id	AC7
Number of Residues	10
Details	binding site for residue HC4 G 101

Chain	Residue
B	GLU13
B	TYR16
D	SER9
G	CYS6
G	SER9
G	ILE10
G	CYS11
H	HIS10
H	LEU11
H	HOH201

---

site_id	AC8
Number of Residues	9
Details	binding site for residue HC4 H 101

Chain	Residue
F	GLU21
G	VAL3
G	GLU4
H	PHE1
H	GLN4
H	HIS5
H	PRO28
H	HOH205
K	ILE10

---

site_id	AC9
Number of Residues	6
Details	binding site for residue PO4 H 102

Chain	Residue
H	PHE1
H	VAL2
H	ASN3
L	PHE1
L	VAL2
L	PO4101

---

site_id	AD1
Number of Residues	10
Details	binding site for residue HC4 K 101

Chain	Residue
F	TYR16
H	HIS5
H	SER9
K	CYS6
K	SER9
K	ILE10
K	CYS11
K	HOH213
L	HIS10
L	HOH203

---

site_id	AD2
Number of Residues	7
Details	binding site for residue PO4 L 101

Chain	Residue
D	ASN3
D	HC4102
E	GLY1
H	ASN3
H	PO4102
L	PHE1
L	VAL2

---

Functional Information from PROSITE/UniProt

site_id	PS00262
Number of Residues	15
Details	INSULIN Insulin family signature. CCTSiCSlyqLenyC

Chain	Residue	Details
A	CYS6-CYS20

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	120
Details	Peptide: {"description":"Insulin A chain","featureId":"PRO_0000015821"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	29
Details	Peptide: {"description":"Insulin B chain","featureId":"PRO_0000015819"}

Chain

Residue

Details

---