6WP6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wp6 by Molmil](/molmil-images/mine/6wp6) | Pyruvate Kinase M2 mutant-S37E K433E | Descriptor: | GLYCEROL, MAGNESIUM ION, NITRATE ION, ... | Authors: | Nandi, S, Razzaghi, M, Srivastava, D, Dey, M. | Deposit date: | 2020-04-26 | Release date: | 2020-10-07 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural basis for allosteric regulation of pyruvate kinase M2 by phosphorylation and acetylation. J.Biol.Chem., 295, 2020
|
|
7UKH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ukh by Molmil](/molmil-images/mine/7ukh) | Human Kv4.2-KChIP2-DPP6 channel complex in an open state, intracellular region | Descriptor: | CALCIUM ION, Isoform 2 of Kv channel-interacting protein 2, Potassium voltage-gated channel subfamily D member 2, ... | Authors: | Zhao, H, Dai, Y, Lee, C.H. | Deposit date: | 2022-04-01 | Release date: | 2022-06-29 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.33 Å) | Cite: | Activation and closed-state inactivation mechanisms of the human voltage-gated K V 4 channel complexes. Mol.Cell, 82, 2022
|
|
6YDW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ydw by Molmil](/molmil-images/mine/6ydw) | |
8FKU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fku by Molmil](/molmil-images/mine/8fku) | |
8FKS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fks by Molmil](/molmil-images/mine/8fks) | |
8FKT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fkt by Molmil](/molmil-images/mine/8fkt) | |
6XAV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xav by Molmil](/molmil-images/mine/6xav) | CryoEM Structure of E. coli Rho-dependent Transcription Pre-termination Complex bound with NusG | Descriptor: | DNA (29-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Hao, Z.T, Kim, H.K, Walz, T, Nudler, E. | Deposit date: | 2020-06-04 | Release date: | 2020-12-16 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | Pre-termination Transcription Complex: Structure and Function. Mol.Cell, 81, 2021
|
|
8FKQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fkq by Molmil](/molmil-images/mine/8fkq) | |
3K6G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3k6g by Molmil](/molmil-images/mine/3k6g) | Crystal structure of Rap1 and TRF2 complex | Descriptor: | Telomeric repeat-binding factor 2, Telomeric repeat-binding factor 2-interacting protein 1 | Authors: | Chen, Y, Rai, R, Yang, Y.T, Zheng, H, Chang, S, Lei, M. | Deposit date: | 2009-10-08 | Release date: | 2010-10-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms. Nat.Struct.Mol.Biol., 18, 2011
|
|
6Y8B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6y8b by Molmil](/molmil-images/mine/6y8b) | 14-3-3 Sigma in complex with phosphorylated caspase{pS139} peptide | Descriptor: | 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. | Deposit date: | 2020-03-04 | Release date: | 2020-10-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | A new soaking procedure for X-ray crystallographic structural determination of protein-peptide complexes. Acta Crystallogr.,Sect.F, 76, 2020
|
|
7ZUB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zub by Molmil](/molmil-images/mine/7zub) | Cryo-EM structure of the indirubin-bound Hsp90-XAP2-AHR complex | Descriptor: | (3~{Z})-3-(3-oxidanylidene-1~{H}-indol-2-ylidene)-1~{H}-indol-2-one, ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, ... | Authors: | Gruszczyk, J, Savva, C.G, Lai-Kee-Him, J, Bous, J, Ancelin, A, Kwong, H.S, Grandvuillemin, L, Bourguet, W. | Deposit date: | 2022-05-12 | Release date: | 2022-11-23 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex. Nat Commun, 13, 2022
|
|
8HB0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hb0 by Molmil](/molmil-images/mine/8hb0) | Structure of human SGLT2-MAP17 complex with TA1887 | Descriptor: | (2R,3R,4S,5S,6R)-2-[3-[(4-cyclopropylphenyl)methyl]-4-fluoranyl-indol-1-yl]-6-(hydroxymethyl)oxane-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, PDZK1-interacting protein 1, ... | Authors: | Hiraizumi, M, Kishida, H, Miyaguchi, I, Nureki, O. | Deposit date: | 2022-10-27 | Release date: | 2023-11-01 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Transport and inhibition mechanism of the human SGLT2-MAP17 glucose transporter. Nat.Struct.Mol.Biol., 31, 2024
|
|
8HG7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hg7 by Molmil](/molmil-images/mine/8hg7) | Structure of human SGLT2-MAP17 complex with Sotagliflozin | Descriptor: | (2S,3R,4R,5S,6R)-2-[4-chloranyl-3-[(4-ethoxyphenyl)methyl]phenyl]-6-methylsulfanyl-oxane-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, PDZK1-interacting protein 1, ... | Authors: | Hiraizumi, M, Kishida, H, Miyaguchi, I, Nureki, O. | Deposit date: | 2022-11-14 | Release date: | 2023-11-15 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Transport and inhibition mechanism of the human SGLT2-MAP17 glucose transporter. Nat.Struct.Mol.Biol., 31, 2024
|
|
8HEZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hez by Molmil](/molmil-images/mine/8hez) | Structure of human SGLT2-MAP17 complex with Dapagliflozin | Descriptor: | (2S,3R,4R,5S,6R)-2-[4-chloranyl-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, PDZK1-interacting protein 1, ... | Authors: | Hiraizumi, M, Kishida, H, Miyaguchi, I, Nureki, O. | Deposit date: | 2022-11-09 | Release date: | 2023-11-15 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Transport and inhibition mechanism of the human SGLT2-MAP17 glucose transporter. Nat.Struct.Mol.Biol., 31, 2024
|
|
8HDH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hdh by Molmil](/molmil-images/mine/8hdh) | Structure of human SGLT2-MAP17 complex with Canagliflozin | Descriptor: | (2~{S},3~{R},4~{R},5~{S},6~{R})-2-[3-[[5-(4-fluorophenyl)thiophen-2-yl]methyl]-4-methyl-phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, PDZK1-interacting protein 1, ... | Authors: | Hiraizumi, M, Kishida, H, Miyaguchi, I, Nureki, O. | Deposit date: | 2022-11-04 | Release date: | 2023-11-08 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Transport and inhibition mechanism of the human SGLT2-MAP17 glucose transporter. Nat.Struct.Mol.Biol., 31, 2024
|
|
8HIN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hin by Molmil](/molmil-images/mine/8hin) | Structure of human SGLT2-MAP17 complex with Phlorizin | Descriptor: | 1-[2-[(2S,3R,4S,5S,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4,6-bis(oxidanyl)phenyl]-3-(4-hydroxyphenyl)propan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, PDZK1-interacting protein 1, ... | Authors: | Hiraizumi, M, Kishida, H, Miyaguchi, I, Nureki, O. | Deposit date: | 2022-11-21 | Release date: | 2023-11-22 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Transport and inhibition mechanism of the human SGLT2-MAP17 glucose transporter. Nat.Struct.Mol.Biol., 31, 2024
|
|
8CSR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8csr by Molmil](/molmil-images/mine/8csr) | Human mitochondrial small subunit assembly intermediate (State C) | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Harper, N.J, Burnside, C, Klinge, S. | Deposit date: | 2022-05-13 | Release date: | 2022-12-14 | Last modified: | 2023-02-15 | Method: | ELECTRON MICROSCOPY (2.54 Å) | Cite: | Principles of mitoribosomal small subunit assembly in eukaryotes. Nature, 614, 2023
|
|
8CSS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8css by Molmil](/molmil-images/mine/8css) | Human mitochondrial small subunit assembly intermediate (State D) | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Harper, N.J, Burnside, C, Klinge, S. | Deposit date: | 2022-05-13 | Release date: | 2022-12-14 | Last modified: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (2.36 Å) | Cite: | Principles of mitoribosomal small subunit assembly in eukaryotes. Nature, 614, 2023
|
|
8CSQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8csq by Molmil](/molmil-images/mine/8csq) | Human mitochondrial small subunit assembly intermediate (State B) | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Harper, N.J, Burnside, C, Klinge, S. | Deposit date: | 2022-05-13 | Release date: | 2022-12-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.54 Å) | Cite: | Principles of mitoribosomal small subunit assembly in eukaryotes. Nature, 614, 2023
|
|
8CSU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8csu by Molmil](/molmil-images/mine/8csu) | Human mitochondrial small subunit assembly intermediate (State C*) | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Harper, N.J, Burnside, C, Klinge, S. | Deposit date: | 2022-05-13 | Release date: | 2022-12-14 | Last modified: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Principles of mitoribosomal small subunit assembly in eukaryotes. Nature, 614, 2023
|
|
8CST
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8cst by Molmil](/molmil-images/mine/8cst) | Human mitochondrial small subunit assembly intermediate (State E) | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Harper, N.J, Burnside, C, Klinge, S. | Deposit date: | 2022-05-13 | Release date: | 2022-12-14 | Last modified: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Principles of mitoribosomal small subunit assembly in eukaryotes. Nature, 614, 2023
|
|
6ZFA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zfa by Molmil](/molmil-images/mine/6zfa) | Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with GlcIFG, alpha-1,2-mannobiose and hexatungstotellurate(VI) TEW | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, 6-tungstotellurate(VI), ... | Authors: | Sobala, L.F, Fernandes, P.Z, Hakki, Z, Thompson, A.J, Howe, J.D, Hill, M, Zitzmann, N, Davies, S, Stamataki, Z, Butters, T.D, Alonzi, D.S, Williams, S.J, Davies, G.J. | Deposit date: | 2020-06-16 | Release date: | 2020-11-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6Z9B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6z9b by Molmil](/molmil-images/mine/6z9b) | |
6ZFN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zfn by Molmil](/molmil-images/mine/6zfn) | Structure of an inactive E404Q variant of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with 1-methyl alpha-1,2-mannobiose | Descriptor: | Glycoprotein endo-alpha-1,2-mannosidase, SULFATE ION, alpha-D-mannopyranose-(1-2)-methyl alpha-D-mannopyranoside | Authors: | Sobala, L.F, Fernandes, P.Z, Hakki, Z, Thompson, A.J, Howe, J.D, Hill, M, Zitzmann, N, Davies, S, Stamataki, Z, Butters, T.D, Alonzi, D.S, Williams, S.J, Davies, G.J. | Deposit date: | 2020-06-17 | Release date: | 2020-11-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
3M52
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3m52 by Molmil](/molmil-images/mine/3m52) | Crystal structure of the BTB domain from the Miz-1/ZBTB17 transcription regulator | Descriptor: | ACETATE ION, ZINC ION, Zinc finger and BTB domain-containing protein 17 | Authors: | Stogios, P.J, Cuesta-Seijo, J.A, Chen, L, Prive, G.G. | Deposit date: | 2010-03-12 | Release date: | 2010-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Insights into Strand Exchange in BTB Domain Dimers from the Crystal Structures of FAZF and Miz1. J.Mol.Biol., 400, 2010
|
|