PDB: 31188 resultsInfo pagesStatus searchChemie searchBIRD

---

3OZX	Crystal structure of ABCE1 of Sulfolubus solfataricus (-FeS domain) Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... Authors: Barthelme, D, Tampe, R. Deposit date: 2010-09-27 Release date: 2011-02-02 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Ribosome Recycling in Archaea A Mechanistic Link between FeS Cluster Biosynthesis and Conformational Switch of Twin-ATPase ABCE1 To be Published
3DLW	Antichymotrypsin Descriptor: Alpha-1-antichymotrypsin Authors: Feil, S.C. Deposit date: 2008-06-29 Release date: 2009-07-07 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Identification and characterization of a misfolded monomeric serpin formed at physiological temperature J.Mol.Biol., 403, 2010
2XTJ	The crystal structure of PCSK9 in complex with 1D05 Fab Descriptor: CALCIUM ION, FAB FROM A HUMAN MONOCLONAL ANTIBODY, 1D05, ... Authors: Di Marco, S, Volpari, C, Carfi, A. Deposit date: 2010-10-10 Release date: 2010-11-03 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.7 Å) Cite: A Pcsk9-Binding Antibody that Structurally Mimics the Egf(A) Domain of Ldl-Receptor Reduces Ldl Cholesterol in Vivo. J.Lipid Res., 52, 2011
3PSZ	Crystal Structure of AhQnr, the Qnr protein from Aeromonas hydrophila (P21212 crystal form) Descriptor: ACETATE ION, PHOSPHATE ION, Qnr Authors: Xiong, X, Spencer, J. Deposit date: 2010-12-02 Release date: 2011-01-26 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural insights into quinolone antibiotic resistance mediated by pentapeptide repeat proteins: conserved surface loops direct the activity of a Qnr protein from a Gram-negative bacterium Nucleic Acids Res., 2011
3PSS	Crystal Structure of AhQnr, the Qnr protein from Aeromonas hydrophila (P21 crystal form) Descriptor: Qnr Authors: Xiong, X, Spencer, J. Deposit date: 2010-12-02 Release date: 2011-01-26 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural insights into quinolone antibiotic resistance mediated by pentapeptide repeat proteins: conserved surface loops direct the activity of a Qnr protein from a Gram-negative bacterium Nucleic Acids Res., 2011
3E65	Murine INOS dimer with HEME, pterin and inhibitor AR-C120011 Descriptor: 1-[4-(AMINOMETHYL)BENZOYL]-5'-FLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLIN]-4'-AMINE, 5,6,7,8-TETRAHYDROBIOPTERIN, Nitric oxide synthase, ... Authors: Rosenfeld, R.J, Garcin, E.D, Getzoff, E.D. Deposit date: 2008-08-14 Release date: 2008-10-07 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase. Nat.Chem.Biol., 4, 2008
2ONN	Arg475Gln Mutant of Human Mitochondrial Aldehyde Dehydrogenase, Apo form Descriptor: Aldehyde dehydrogenase Authors: Larson, H.N, Hurley, T.D. Deposit date: 2007-01-24 Release date: 2007-03-06 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487. J.Biol.Chem., 282, 2007
2ONP	Arg475Gln Mutant of Human Mitochondrial Aldehyde Dehydrogenase, complexed with NAD+ Descriptor: 1,2-ETHANEDIOL, Aldehyde dehydrogenase, GUANIDINE, ... Authors: Larson, H.N, Hurley, T.D. Deposit date: 2007-01-24 Release date: 2007-03-06 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487. J.Biol.Chem., 282, 2007
2ONO	Arg475Gln Mutant of Mitochondrial Aldehyde Dehydrogenase, apo form, pseudo-merohedrally twinned Descriptor: Aldehyde dehydrogenase Authors: Larson, H.N, Hurley, T.D. Deposit date: 2007-01-24 Release date: 2007-03-06 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487. J.Biol.Chem., 282, 2007
2ONM	Human Mitochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, complexed with NAD+ Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Aldehyde dehydrogenase, ... Authors: Larson, H.N, Hurley, T.D. Deposit date: 2007-01-24 Release date: 2007-03-06 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487. J.Biol.Chem., 282, 2007
2PEE	Crystal Structure of a Thermophilic Serpin, Tengpin, in the Native State Descriptor: GLYCEROL, SULFATE ION, Serine protease inhibitor Authors: Zhang, Q.W, Buckle, A.M, Whisstock, J.C. Deposit date: 2007-04-02 Release date: 2007-06-19 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.7 Å) Cite: The N terminus of the serpin, tengpin, functions to trap the metastable native state. Embo Rep., 8, 2007
6D1Z	Crystal structure of Tyrosine-protein kinase receptor in complex with 5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one Inhibitor Descriptor: 5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one, 5-{[5-(6-aminopyridin-2-yl)-2-chlorobenzene-1-carbonyl]amino}-1-phenyl-1H-pyrazole-3-carboxamide, GLYCEROL, ... Authors: Greasley, S.E, Johnson, E, Kraus, M.L, Cronin, C.N. Deposit date: 2018-04-12 Release date: 2018-05-02 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Discovery of Allosteric, Potent, Subtype Selective, and Peripherally Restricted TrkA Kinase Inhibitors. J. Med. Chem., 62, 2019
5VHB	Crystal structure of Protein Kinase A in complex with the PKI peptide and Aminobenzothiazole based inhibitor Descriptor: N-[(2S)-1-hydroxy-3-phenylpropan-2-yl]-4-(pyridin-4-yl)benzamide, PKI peptide, cAMP-dependent protein kinase catalytic subunit alpha Authors: Judge, R.A. Deposit date: 2017-04-12 Release date: 2018-01-31 Last modified: 2018-04-04 Method: X-RAY DIFFRACTION (1.61 Å) Cite: Design of Aminobenzothiazole Inhibitors of Rho Kinases 1 and 2 by Using Protein Kinase A as a Structure Surrogate. Chembiochem, 19, 2018
5VI9	Crystal structure of Protein Kinase A in complex with the PKI peptide and Aminobenzothiazole based inhibitors Descriptor: N-[(3-fluorophenyl)methyl]-6-(pyridin-4-yl)-1,3-benzothiazol-2-amine, PKI peptide, cAMP-dependent protein kinase catalytic subunit alpha Authors: Judge, R.A. Deposit date: 2017-04-14 Release date: 2018-01-31 Last modified: 2018-04-04 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Design of Aminobenzothiazole Inhibitors of Rho Kinases 1 and 2 by Using Protein Kinase A as a Structure Surrogate. Chembiochem, 19, 2018
2PEF	Crystal Structure of a Thermophilic Serpin, Tengpin, in the Latent State Descriptor: Serine protease inhibitor Authors: Zhang, Q.W, Buckle, A.M, Whisstock, J.C. Deposit date: 2007-04-03 Release date: 2007-06-19 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.6 Å) Cite: The N terminus of the serpin, tengpin, functions to trap the metastable native state. Embo Rep., 8, 2007
2R6W	Estrogen receptor alpha ligand-binding domain complexed to a SERM Descriptor: Estrogen receptor, [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothien-3-yl]{4-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl}methanone Authors: Wang, Y. Deposit date: 2007-09-06 Release date: 2008-04-08 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2 Å) Cite: Prediction of the tissue-specificity of selective estrogen receptor modulators by using a single biochemical method. Proc.Natl.Acad.Sci.Usa, 105, 2008
2R6Y	Estrogen receptor alpha ligand-binding domain in complex with a SERM Descriptor: Estrogen receptor, [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothien-3-yl][4-(2-pyrrolidin-1-ylethoxy)phenyl]methanone Authors: Wang, Y. Deposit date: 2007-09-06 Release date: 2008-04-08 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2 Å) Cite: Prediction of the tissue-specificity of selective estrogen receptor modulators by using a single biochemical method. Proc.Natl.Acad.Sci.Usa, 105, 2008
3QTE	Crystal structure of human alpha-defensin 6 (H27W mutant) Descriptor: CHLORIDE ION, Defensin-6, GLYCEROL Authors: Pazgier, M, Lu, W. Deposit date: 2011-02-22 Release date: 2012-01-11 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.949 Å) Cite: Human alpha-defensin 6 promotes mucosal innate immunity through self-assembled peptide nanonets. Science, 337, 2012
3RFR	Crystal Structure of particulate methane monooxygenase (pMMO) from Methylocystis sp. strain M Descriptor: COPPER (II) ION, DINUCLEAR COPPER ION, PmoA, ... Authors: Smith, S.M, Rosenzweig, A.C. Deposit date: 2011-04-06 Release date: 2011-11-23 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.68 Å) Cite: Crystal Structure and Characterization of Particulate Methane Monooxygenase from Methylocystis species Strain M. Biochemistry, 50, 2011
3RGB	Crystal structure of particulate methane monooxygenase from Methylococcus capsulatus (Bath) Descriptor: COPPER (II) ION, DINUCLEAR COPPER ION, Methane monooxygenase subunit A2, ... Authors: Smith, S.M, Rosenzweig, A.C. Deposit date: 2011-04-08 Release date: 2011-11-23 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal Structure and Characterization of Particulate Methane Monooxygenase from Methylocystis species Strain M. Biochemistry, 50, 2011
7KQD	Prefusion RSV F Bound to RV521 Descriptor: 1'-{[5-(aminomethyl)-1-(4,4,4-trifluorobutyl)-1H-benzimidazol-2-yl]methyl}-6'-fluorospiro[cyclopropane-1,3'-indol]-2'(1'H)-one, Fusion glycoprotein F0, SULFATE ION Authors: McLellan, J.S. Deposit date: 2020-11-14 Release date: 2021-04-21 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.94 Å) Cite: Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion. J.Med.Chem., 64, 2021
7MDP	KRas G12C in complex with G-2897 Descriptor: 1,2-ETHANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, 4-(trifluoromethyl)-1,3-benzothiazol-2-amine, ... Authors: Oh, A, Frank, Y, Wang, W. Deposit date: 2021-04-05 Release date: 2022-03-16 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors. Nat.Biotechnol., 40, 2022
7MWY	Structure of the drosophila STING cyclic dinucleotide binding domain Descriptor: STING Authors: Slavik, K.M, Ragucci, A.E, Kranzusch, P.J. Deposit date: 2021-05-17 Release date: 2021-07-21 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.84 Å) Cite: cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila. Nature, 597, 2021
7MWZ	Structure of drosophila STING in complex with 3'2'-cGAMP Descriptor: 3'2'-cGAMP, STING Authors: Slavik, K.M, Ragucci, A.E, Kranzusch, P.J. Deposit date: 2021-05-17 Release date: 2021-07-21 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2 Å) Cite: cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila. Nature, 597, 2021
7LT1	Structure of the cGAS-like receptor human MB21D2 Descriptor: Protein MB21D2, SULFATE ION Authors: Morehouse, B.R, Slavik, K.M, Kranzusch, P.J. Deposit date: 2021-02-18 Release date: 2021-07-21 Last modified: 2021-09-15 Method: X-RAY DIFFRACTION (2.4 Å) Cite: cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila. Nature, 597, 2021

<12131415161718192021222324252627>