2ONP
Arg475Gln Mutant of Human Mitochondrial Aldehyde Dehydrogenase, complexed with NAD+
Summary for 2ONP
Entry DOI | 10.2210/pdb2onp/pdb |
Descriptor | Aldehyde dehydrogenase, MAGNESIUM ION, SODIUM ION, ... (7 entities in total) |
Functional Keywords | oxidoreductase, aldh, nad, rossmann fold |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion matrix: P05091 |
Total number of polymer chains | 8 |
Total formula weight | 445524.87 |
Authors | Larson, H.N.,Hurley, T.D. (deposition date: 2007-01-24, release date: 2007-03-06, Last modification date: 2023-08-30) |
Primary citation | Larson, H.N.,Zhou, J.,Chen, Z.,Stamler, J.S.,Weiner, H.,Hurley, T.D. Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487. J.Biol.Chem., 282:12940-12950, 2007 Cited by PubMed: 17327228DOI: 10.1074/jbc.M607959200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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