PDB: 453 件ウェブページステータス検索Chemie searchBIRD

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1NB5	Crystal structure of stefin A in complex with cathepsin H 分子名称: Cathepsin H, Cathepsin H MINI CHAIN, STEFIN A, ... 著者 Jenko, S, Dolenc, I, Guncar, G, Dobersek, A, Podobnik, M, Turk, D. 登録日 2002-12-02 公開日 2003-02-18 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of stefin A in complex with cathepsin H: N-terminal residues of inhibitors can adapt to the active sites of endo- and exopeptidases J.Mol.Biol., 326, 2003
1NB3	Crystal structure of stefin A in complex with cathepsin H: N-terminal residues of inhibitors can adapt to the active sites of endo-and exopeptidases 分子名称: CATHEPSIN H MINI CHAIN, Cathepsin H, Stefin A, ... 著者 Jenko, S, Dolenc, I, Guncar, G, Dobersek, A, Podobnik, M, Turk, D. 登録日 2002-12-02 公開日 2003-02-18 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of stefin A in complex with cathepsin H: N-terminal residues of inhibitors can adapt to the active sites of endo- and exopeptidases J.Mol.Biol., 326, 2003
1MS6	Dipeptide Nitrile Inhibitor Bound to Cathepsin S. 分子名称: Cathepsin S, MORPHOLINE-4-CARBOXYLIC ACID [1S-(2-BENZYLOXY-1R-CYANO-ETHYLCARBAMOYL)-3-METHYL-BUTYL]AMIDE 著者 Ward, Y.D, Thomson, D.S, Frye, L.L, Cywin, C.L, Morwick, T, Emmanuel, M.J, Zindell, R, McNeil, D, Bekkali, Y, Giradot, M, Hrapchak, M, DeTuri, M, Crane, K, White, D, Pav, S, Wang, Y, Hao, M.H, Grygon, C.A, Labadia, M.E, Freeman, D.M, Davidson, W, Hopkins, J.L, Brown, M.L, Spero, D.M. 登録日 2002-09-19 公開日 2003-04-22 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Design and synthesis of dipeptide nitriles as reversible and potent Cathepsin S inhibitors J.Med.Chem., 45, 2002
1MIR	RAT PROCATHEPSIN B 分子名称: PROCATHEPSIN B 著者 Cygler, M, Sivaraman, J, Grochulski, P, Coulombe, R, Storer, A.C, Mort, J.S. 登録日 1996-01-12 公開日 1997-01-11 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion. Structure, 4, 1996
1MHW	Design of non-covalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides 分子名称: 4-biphenylacetyl-Cys-(D)Arg-Tyr-N-(2-phenylethyl) amide, Cathepsin L 著者 Chowdhury, S, Sivaraman, J, Wang, J, Devanathan, G, Lachance, P, Qi, H, Menard, R, Lefebvre, J, Konishi, Y, Cygler, M, Sulea, T, Purisima, E.O. 登録日 2002-08-21 公開日 2002-12-11 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Design of non-covalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides J.Med.Chem., 45, 2002
1MEM	Crystal structure of Cathepsin K complexed with a potent vinyl sulfone inhibitor 分子名称: Cathepsin K, N-{(1R)-3-phenyl-1-[2-(phenylsulfonyl)ethyl]propyl}-N~2~-(piperazin-1-ylcarbonyl)-L-leucinamide 著者 Mcgrath, M.E. 登録日 1997-01-08 公開日 1998-01-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of human cathepsin K complexed with a potent inhibitor. Nat.Struct.Biol., 4, 1997
1MEG	CRYSTAL STRUCTURE OF A CARICAIN D158E MUTANT IN COMPLEX WITH E-64 分子名称: CARICAIN, ETHANOL, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE 著者 Katerelos, N.A. 登録日 1996-05-04 公開日 1997-01-11 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of a caricain D158E mutant in complex with E-64. FEBS Lett., 392, 1996
1ME4	High Resolution Crystal Structure Analysis Of Cruzain non-covalently Bound To A Hydroxymethyl Ketone Inhibitor (I) 分子名称: CRUZIPAIN, [1-(1-BENZYL-3-HYDROXY-2-OXO-PROPYLCARBAMOYL)-2-PHENYL-ETHYL]-CARBAMIC ACID BENZYL ESTER 著者 Brinen, L.S, Huang, L, Ellman, J.A. 登録日 2002-08-07 公開日 2002-12-18 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Crystal Structures of Reversible Ketone-based Inhibitors of the Cysteine Protease Cruzain Bioorg.Med.Chem., 11, 2003
1ME3	High Resolution Crystal Structure Analysis Of Cruzain non-covalently Bound To A Hydroxymethyl Ketone Inhibitor (II) 分子名称: Cruzipain, [1-(3-HYDROXY-2-OXO-1-PHENETHYL-PROPYLCARBAMOYL)2-PHENYL-ETHYL]-CARBAMIC ACID PYRIDIN-4-YLMETHYL ESTER 著者 Brinen, L.S, Huang, L, Ellman, J.A. 登録日 2002-08-07 公開日 2002-12-18 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Crystal Structures of Reversible Ketone-based Inhibitors of the Cysteine Protease Cruzain Bioorg.Med.Chem., 11, 2003
1M6D	Crystal structure of human cathepsin F 分子名称: 4-MORPHOLIN-4-YL-PIPERIDINE-1-CARBOXYLIC ACID [1-(3-BENZENESULFONYL-1-PROPYL-ALLYLCARBAMOYL)-2-PHENYLETHYL]-AMIDE, Cathepsin F 著者 Somoza, J.R, Palmer, J.T, Ho, J.D. 登録日 2002-07-15 公開日 2003-07-15 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The crystal structure of human cathepsin F and its implications for the development of novel immunomodulators J.Mol.Biol., 322, 2002
1KHQ	ORTHORHOMBIC FORM OF PAPAIN/ZLFG-DAM COVALENT COMPLEX 分子名称: Papain, peptidic inhibitor 著者 Janowski, R, Kozak, M, Jankowska, E, Grzonka, Z, Jaskolski, M. 登録日 2001-11-30 公開日 2003-09-09 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Two polymorphs of a covalent complex between papain and a diazomethylketone inhibitor J.Pept.Res., 64, 2004
1KHP	Monoclinic form of papain/ZLFG-DAM covalent complex 分子名称: Papain, peptidic inhibitor 著者 Janowski, R, Kozak, M, Jankowska, E, Grzonka, Z, Jaskolski, M. 登録日 2001-11-30 公開日 2003-09-09 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Two polymorphs of a covalent complex between papain and a diazomethylketone inhibitor J.Pept.Res., 64, 2004
1K3B	Crystal Structure of Human Dipeptidyl Peptidase I (Cathepsin C): Exclusion Domain Added to an Endopeptidase Framework Creates the Machine for Activation of Granular Serine Proteases 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, SULFATE ION, ... 著者 Turk, D, Janjic, V, Stern, I, Podobnik, M, Lamba, D, Dahl, S.W, Lauritzen, C, Pedersen, J, Turk, V, Turk, B. 登録日 2001-10-02 公開日 2002-04-02 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structure of human dipeptidyl peptidase I (cathepsin C): exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteases. EMBO J., 20, 2001
1JQP	dipeptidyl peptidase I (cathepsin C), a tetrameric cysteine protease of the papain family 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, SULFATE ION, ... 著者 Olsen, J.G, Kadziola, A, Lauritzen, C, Pedersen, J, Larsen, S, Dahl, S.W. 登録日 2001-08-08 公開日 2002-10-18 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Tetrameric dipeptidyl peptidase I directs substrate specificity by use of the residual pro-part domain FEBS LETT., 506, 2001
1IWD	Proposed Amino Acid Sequence and the 1.63 Angstrom X-ray Crystal Structure of a Plant Cysteine Protease Ervatamin B: Insight into the Structural Basis of its Stability and Substrate Specificity. 分子名称: ERVATAMIN B, THIOSULFATE 著者 Chakrabarti, C, Biswas, S, Dattagupta, J.K. 登録日 2002-05-02 公開日 2003-05-06 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Proposed amino acid sequence and the 1.63 A X-ray crystal structure of a plant cysteine protease, ervatamin B: Some insights into the structural basis of its stability and substrate specificity Proteins, 51, 2003
1ITO	Crystal Structure Analysis of Bovine Spleen Cathepsin B-E64c complex 分子名称: Cathepsin B, N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-2-METHYL-BUTANE 著者 Yamamoto, A, Tomoo, T, Matsugi, K, Hara, T, In, Y, Murata, M, Kitamura, K, Ishida, T. 登録日 2002-01-19 公開日 2003-01-19 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.286 Å) 主引用文献 Structural basis for development of cathepsin B-specific noncovalent-type inhibitor: crystal structure of cathepsin B-E64c complex BIOCHIM.BIOPHYS.ACTA, 1597, 2002
1ICF	CRYSTAL STRUCTURE OF MHC CLASS II ASSOCIATED P41 II FRAGMENT IN COMPLEX WITH CATHEPSIN L 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (CATHEPSIN L: HEAVY CHAIN), PROTEIN (CATHEPSIN L: LIGHT CHAIN), ... 著者 Guncar, G, Pungercic, G, Klemencic, I, Turk, V, Turk, D. 登録日 1999-01-07 公開日 2000-01-12 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of MHC class II-associated p41 Ii fragment bound to cathepsin L reveals the structural basis for differentiation between cathepsins L and S. EMBO J., 18, 1999
1HUC	THE REFINED 2.15 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF HUMAN LIVER CATHEPSIN B: THE STRUCTURAL BASIS FOR ITS SPECIFICITY 分子名称: CATHEPSIN B 著者 Musil, D, Bode, W. 登録日 1993-04-21 公開日 1995-01-26 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The refined 2.15 A X-ray crystal structure of human liver cathepsin B: the structural basis for its specificity. EMBO J., 10, 1991
1GMY	Cathepsin B complexed with dipeptidyl nitrile inhibitor 分子名称: 2-AMINOETHANIMIDIC ACID, 3-METHYLPHENYLALANINE, CATHEPSIN B, ... 著者 Greenspan, P.D, Clark, K.L, Tommasi, R.A, Cowen, S.D, McQuire, L.W, Farley, D.L, van Duzer, J.H, Goldberg, R.L, Zhou, H, Du, Z, Fitt, J.J, Coppa, D.E, Fang, Z, Macchia, W, Zhu, L, Capparelli, M.P, Goldstein, R, Wigg, A.M, Doughty, J.R, Bohacek, R.S, Knap, A.K. 登録日 2001-09-25 公開日 2002-09-19 最終更新日 2017-07-05 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Identification of Dipeptidyl Nitriles as Potent and Selective Inhibitors of Cathepsin B Through Structure-Based Drug Design J.Med.Chem., 44, 2001
1GLO	Crystal Structure of Cys25Ser mutant of human cathepsin S 分子名称: CATHEPSIN S 著者 Turkenburg, J.P, Lamers, M.B.A.C, Brzozowski, A.M, Wright, L.M, Hubbard, R.E, Sturt, S.L, Williams, D.H. 登録日 2001-08-31 公開日 2002-08-29 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of a Cys25->Ser Mutant of Human Cathepsin Cathepsin S Acta Crystallogr.,Sect.D, 58, 2002
1GEC	GLYCYL ENDOPEPTIDASE-COMPLEX WITH BENZYLOXYCARBONYL-LEUCINE-VALINE-GLYCINE-METHYLENE COVALENTLY BOUND TO CYSTEINE 25 分子名称: BENZYLOXYCARBONYL-LEUCINE-VALINE-GLYCINE-METHYLENE INHIBITOR, GLYCYL ENDOPEPTIDASE 著者 Ohara, B.P, Hemmings, A.M, Buttle, D.J, Pearl, L.H. 登録日 1995-05-25 公開日 1995-12-07 最終更新日 2012-12-12 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of glycyl endopeptidase from Carica papaya: a cysteine endopeptidase of unusual substrate specificity. Biochemistry, 34, 1995
1FH0	CRYSTAL STRUCTURE OF HUMAN CATHEPSIN V COMPLEXED WITH AN IRREVERSIBLE VINYL SULFONE INHIBITOR 分子名称: CATHEPSIN V, Nalpha-[(4-methylpiperazin-1-yl)carbonyl]-N-[(3S)-1-phenyl-5-(phenylsulfonyl)pentan-3-yl]-L-phenylalaninamide, SULFATE ION 著者 Somoza, J.R. 登録日 2000-07-30 公開日 2001-07-30 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of human cathepsin V. Biochemistry, 39, 2000
1F2C	CRYSTAL STRUCTURE ANALYSIS OF CRYZAIN BOUND TO VINYL SULFONE DERIVED INHIBITOR (IV) 分子名称: 3-[[N-[4-METHYL-PIPERAZINYL]CARBONYL]-PHENYLALANINYL-AMINO]-5-PHENYL-PENTANE-1-SULFONIC ACID BENZYLOXY-AMIDE, CRUZAIN 著者 Brinen, L.S, Hansell, E, Roush, W.R, McKerrow, J.H, Fletterick, R.J. 登録日 2000-05-23 公開日 2000-07-26 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A target within the target: probing cruzain's P1' site to define structural determinants for the Chagas' disease protease. Structure Fold.Des., 8, 2000
1F2B	CRYSTAL STRUCTURE ANALYSIS OF CRUZAIN BOUND TO VINYL SULFONE DERIVED INHIBITOR (III) 分子名称: 3-[N-[BENZYLOXYCARBONYL]-PHENYLALANINYL-AMINO]-5-PHENYL-PENTANE-1-SULFONIC ACID 4-NITRO-PHENYL ESTER, CRUZAIN 著者 Brinen, L.S, Hansell, E, Roush, W.R, McKerrow, J.H, Fletterick, R.J. 登録日 2000-05-23 公開日 2000-07-26 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A target within the target: probing cruzain's P1' site to define structural determinants for the Chagas' disease protease. Structure Fold.Des., 8, 2000
1F2A	CRYSTAL STRUCTURE ANALYSIS OF CRUZAIN BOUND TO A VINYL SULFONE DERIVED INHIBITOR (II) 分子名称: 3-[N-[BENZYLOXYCARBONYL]-PHENYLALANINYL-AMINO]-5-PHENYL-PENTANE-1-SULFONYLMETHYLBENZENE, CRUZAIN 著者 Brinen, L.S, Hansell, E, Roush, W.R, McKerrow, J.H, Fletterick, R.J. 登録日 2000-05-23 公開日 2000-07-26 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A target within the target: probing cruzain's P1' site to define structural determinants for the Chagas' disease protease. Structure Fold.Des., 8, 2000

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