1NB3

Crystal structure of stefin A in complex with cathepsin H: N-terminal residues of inhibitors can adapt to the active sites of endo-and exopeptidases

Summary for 1NB3

Related1nb5
DescriptorCathepsin H, CATHEPSIN H MINI CHAIN, Stefin A, ... (6 entities in total)
Functional Keywordscysteine proteinase, aminopeptidase, cystatin, enzyme-inhibitor complex, hydrolase
Biological sourceHomo sapiens (human)
More
Cellular locationLysosome O46427 O46427
Cytoplasm  P01040
Total number of polymer chains12
Total molecular weight147281.74
Authors
Jenko, S.,Dolenc, I.,Guncar, G.,Dobersek, A.,Podobnik, M.,Turk, D. (deposition date: 2002-12-02, release date: 2003-02-18, Last modification date: 2018-04-04)
Primary citation
Jenko, S.,Dolenc, I.,Guncar, G.,Dobersek, A.,Podobnik, M.,Turk, D.
Crystal structure of stefin A in complex with cathepsin H: N-terminal residues of inhibitors can adapt to the active sites of endo- and exopeptidases
J.Mol.Biol., 326:875-885, 2003
PubMed: 12581647 (PDB entries with the same primary citation)
DOI: 10.1016/S0022-2836(02)01432-8
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
NMR Information
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.204352.8%19.5%0.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload