1ITO
Crystal Structure Analysis of Bovine Spleen Cathepsin B-E64c complex
Summary for 1ITO
Entry DOI | 10.2210/pdb1ito/pdb |
Related | 1DQD |
Descriptor | Cathepsin B, N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-2-METHYL-BUTANE (3 entities in total) |
Functional Keywords | cathepsin b, cysteine protease, e64c, hydrolase |
Biological source | Bos taurus (cattle) |
Cellular location | Lysosome : P07688 |
Total number of polymer chains | 1 |
Total formula weight | 28235.43 |
Authors | Yamamoto, A.,Tomoo, T.,Matsugi, K.,Hara, T.,In, Y.,Murata, M.,Kitamura, K.,Ishida, T. (deposition date: 2002-01-19, release date: 2003-01-19, Last modification date: 2023-10-25) |
Primary citation | Yamamoto, A.,Tomoo, T.,Matsugi, K.,Hara, T.,In, Y.,Murata, M.,Kitamura, K.,Ishida, T. Structural basis for development of cathepsin B-specific noncovalent-type inhibitor: crystal structure of cathepsin B-E64c complex BIOCHIM.BIOPHYS.ACTA, 1597:244-251, 2002 Cited by PubMed: 12044902DOI: 10.1016/S0167-4838(02)00284-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.286 Å) |
Structure validation
Download full validation report