1NB5

Crystal structure of stefin A in complex with cathepsin H

Summary for 1NB5

Related1NB3
DescriptorCathepsin H, Cathepsin H MINI CHAIN, STEFIN A, ... (5 entities in total)
Functional Keywordscysteine proteinase, aminopeptidase, cystatin, enzyme-inhibitor complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
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Cellular locationLysosome O46427 O46427
Cytoplasm P01040
Total number of polymer chains12
Total molecular weight147281.74
Authors
Jenko, S.,Dolenc, I.,Guncar, G.,Dobersek, A.,Podobnik, M.,Turk, D. (deposition date: 2002-12-02, release date: 2003-02-18, Last modification date: 2011-07-13)
Primary citation
Jenko, S.,Dolenc, I.,Guncar, G.,Dobersek, A.,Podobnik, M.,Turk, D.
Crystal structure of stefin A in complex with cathepsin H: N-terminal residues of inhibitors can adapt to the active sites of endo- and exopeptidases
J.Mol.Biol., 326:875-885, 2003
PubMed: 12581647 (PDB entries with the same primary citation)
DOI: 10.1016/S0022-2836(02)01432-8
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.4 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.276353.0%18.7%12.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload