1ICF

CRYSTAL STRUCTURE OF MHC CLASS II ASSOCIATED P41 II FRAGMENT IN COMPLEX WITH CATHEPSIN L

Summary for 1ICF

• Entry DOI: 10.2210/pdb1icf/pdb
• Descriptor: PROTEIN (CATHEPSIN L: HEAVY CHAIN), PROTEIN (CATHEPSIN L: LIGHT CHAIN), PROTEIN (INVARIANT CHAIN), ... (5 entities in total)
• Functional Keywords: cysteine proteinase, cathepsin, mhc class ii, invariant chain, thyroglobulin type-1 domain, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 62721.42

Authors

Guncar, G.,Pungercic, G.,Klemencic, I.,Turk, V.,Turk, D. (deposition date: 1999-01-07, release date: 2000-01-12, Last modification date: 2023-08-09)

• Primary citation: Guncar, G.,Pungercic, G.,Klemencic, I.,Turk, V.,Turk, D.; Crystal structure of MHC class II-associated p41 Ii fragment bound to cathepsin L reveals the structural basis for differentiation between cathepsins L and S.; EMBO J., 18:793-803, 1999; PubMed: 10022822; DOI: 10.1093/emboj/18.4.793

Experimental method

X-RAY DIFFRACTION (2 Å)