Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5VIH
DownloadVisualize
BU of 5vih by Molmil
Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-fluorophenyl-ACEPC
Descriptor: 5-[(2R)-2-amino-2-carboxyethyl]-1-(4-fluorophenyl)-1H-pyrazole-3-carboxylic acid, DI(HYDROXYETHYL)ETHER, GLYCINE, ...
Authors:Mou, T.-C, Conti, P, Pinto, A, Tamborini, L, Sprang, S.R, Hansen, K.B.
Deposit date:2017-04-16
Release date:2017-04-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of subunit selectivity for competitive NMDA receptor antagonists with preference for GluN2A over GluN2B subunits.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5VIJ
DownloadVisualize
BU of 5vij by Molmil
Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-bromophenyl-ACEPC
Descriptor: 5-[(2R)-2-amino-2-carboxyethyl]-1-(4-bromophenyl)-1H-pyrazole-3-carboxylic acid, GLYCINE, Glutamate receptor ionotropic, ...
Authors:Mou, T.-C, Conti, P, Pinto, A, Tamborini, L, Sprang, S.R, Hansen, K.B.
Deposit date:2017-04-16
Release date:2017-04-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:Structural basis of subunit selectivity for competitive NMDA receptor antagonists with preference for GluN2A over GluN2B subunits.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3PMW
DownloadVisualize
BU of 3pmw by Molmil
Ligand-binding domain of GluA2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
Descriptor: DIMETHYL SULFOXIDE, GLUTAMIC ACID, GLYCEROL, ...
Authors:Maclean, J.K.F, Jamieson, C, Brown, C.I, Campbell, R.A, Gillen, K.J, Gillespie, J, Kazemier, B, Kiczun, M, Lamont, Y, Lyons, A.J, Moir, E.M, Morrow, J.A, Pantling, J, Rankovic, Z, Smith, L.
Deposit date:2010-11-18
Release date:2011-01-12
Last modified:2023-05-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure based evolution of a novel series of positive modulators of the AMPA receptor.
Bioorg.Med.Chem.Lett., 21, 2011
6HCB
DownloadVisualize
BU of 6hcb by Molmil
STRUCTURE OF GLUA2 LIGAND-BINDING DOMAIN (S1S2J-N775S) IN COMPLEX WITH GLUTAMATE AND TDPAM01 AT 1.9 A RESOLUTION.
Descriptor: 6,6'-(Ethane-1,2-diyl)bis(4-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide), CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Laulumaa, S, Masternak, M, Frydenvang, K, Kastrup, J.S.
Deposit date:2018-08-14
Release date:2019-04-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structures of Potent Dimeric Positive Allosteric Modulators at the Ligand-Binding Domain of the GluA2 Receptor.
Acs Med.Chem.Lett., 10, 2019
5VHW
DownloadVisualize
BU of 5vhw by Molmil
GluA2-0xGSG1L bound to ZK
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
Authors:Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I.
Deposit date:2017-04-13
Release date:2017-05-03
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes.
Neuron, 94, 2017
5VHY
DownloadVisualize
BU of 5vhy by Molmil
GluA2-2xGSG1L bound to ZK
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
Authors:Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I.
Deposit date:2017-04-13
Release date:2017-05-03
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes.
Neuron, 94, 2017
3PMX
DownloadVisualize
BU of 3pmx by Molmil
Ligand-binding domain of GluA2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
Descriptor: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, GLUTAMIC ACID, ...
Authors:Maclean, J.K.F, Jamieson, C, Brown, C.I, Campbell, R.A, Gillen, K.J, Gillespie, J, Kazemier, B, Kiczun, M, Lamont, Y, Lyons, A.J, Moir, E.M, Morrow, J.A, Pantling, J, Rankovic, Z, Smith, L.
Deposit date:2010-11-18
Release date:2011-01-12
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structure based evolution of a novel series of positive modulators of the AMPA receptor.
Bioorg.Med.Chem.Lett., 21, 2011
5VOU
DownloadVisualize
BU of 5vou by Molmil
Structure of AMPA receptor-TARP complex
Descriptor: Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Chen, S, Zhao, Y, Wang, Y.S, Shekhar, M, Tajkhorshid, E, Gouaux, E.
Deposit date:2017-05-03
Release date:2017-07-12
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM.
Cell, 170, 2017
5VOT
DownloadVisualize
BU of 5vot by Molmil
Structure of AMPA receptor-TARP complex
Descriptor: Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Chen, S, Zhao, Y, Wang, Y.S, Shekhar, M, Tajkhorshid, E, Gouaux, E.
Deposit date:2017-05-03
Release date:2017-07-12
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM.
Cell, 170, 2017
3PMV
DownloadVisualize
BU of 3pmv by Molmil
Ligand-binding domain of GluA2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
Descriptor: GLUTAMIC ACID, GLYCEROL, Glutamate receptor 2, ...
Authors:Maclean, J.K.F, Jamieson, C, Brown, C.I, Campbell, R.A, Gillen, K.J, Gillespie, J, Kazemier, B, Kiczun, M, Lamont, Y, Lyons, A.J, Moir, E.M, Morrow, J.A, Pantling, J, Rankovic, Z, Smith, L.
Deposit date:2010-11-18
Release date:2011-01-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure based evolution of a novel series of positive modulators of the AMPA receptor.
Bioorg.Med.Chem.Lett., 21, 2011
5VHZ
DownloadVisualize
BU of 5vhz by Molmil
GluA2-2xGSG1L bound to L-Quisqualate
Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2,Germ cell-specific gene 1-like protein
Authors:Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I.
Deposit date:2017-04-13
Release date:2017-05-03
Last modified:2017-11-08
Method:ELECTRON MICROSCOPY (8.4 Å)
Cite:Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes.
Neuron, 94, 2017
5VOV
DownloadVisualize
BU of 5vov by Molmil
Structure of AMPA receptor-TARP complex
Descriptor: Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Zhao, Y, Chen, S, Wang, Y.S, Shekhar, M, Tajkhorshid, E, Gouaux, E.
Deposit date:2017-05-03
Release date:2017-07-12
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM.
Cell, 170, 2017
3OEL
DownloadVisualize
BU of 3oel by Molmil
Crystal structure of GluN2D ligand-binding core in complex with D-glutamate
Descriptor: D-GLUTAMIC ACID, Glutamate [NMDA] receptor subunit epsilon-4
Authors:Simorowski, N, Furukawa, H.
Deposit date:2010-08-12
Release date:2011-05-11
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors.
Nat Commun, 2, 2011
3OEN
DownloadVisualize
BU of 3oen by Molmil
Crystal structure of GluN2D ligand-binding core in complex with L-glutamate
Descriptor: GLUTAMIC ACID, Glutamate [NMDA] receptor subunit epsilon-4
Authors:Simorowski, N, Furukawa, H.
Deposit date:2010-08-12
Release date:2011-05-11
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors.
Nat Commun, 2, 2011
3OEK
DownloadVisualize
BU of 3oek by Molmil
Crystal structure of GluN2D ligand-binding core in complex with L-aspartate
Descriptor: ASPARTIC ACID, Glutamate [NMDA] receptor subunit epsilon-4
Authors:Simorowski, N, Furukawa, H.
Deposit date:2010-08-12
Release date:2011-05-11
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors.
Nat Commun, 2, 2011
6KSP
DownloadVisualize
BU of 6ksp by Molmil
Rat GluD1 receptor(splayed conformation) in complex with 7-CKA and Calcium ions
Descriptor: Glutamate receptor ionotropic, delta-1
Authors:Burada, A.P, Kumar, J.
Deposit date:2019-08-24
Release date:2020-01-15
Last modified:2020-01-29
Method:ELECTRON MICROSCOPY (8.1 Å)
Cite:Cryo-EM structures of the ionotropic glutamate receptor GluD1 reveal a non-swapped architecture.
Nat.Struct.Mol.Biol., 27, 2020
6KZM
DownloadVisualize
BU of 6kzm by Molmil
GluK3 receptor complex with kainate
Descriptor: Glutamate receptor ionotropic, kainate 3
Authors:Kumar, J, Kumari, J, Burada, A.P.
Deposit date:2019-09-24
Release date:2020-03-04
Method:ELECTRON MICROSCOPY (9.6 Å)
Cite:Structural dynamics of the GluK3-kainate receptor neurotransmitter binding domains revealed by cryo-EM.
Int.J.Biol.Macromol., 149, 2020
6L6F
DownloadVisualize
BU of 6l6f by Molmil
GluK3 receptor complex with UBP301
Descriptor: Glutamate receptor ionotropic, kainate 3
Authors:Kumar, J, Kumari, J, Burada, A.P.
Deposit date:2019-10-28
Release date:2020-03-04
Method:ELECTRON MICROSCOPY (10.6 Å)
Cite:Structural dynamics of the GluK3-kainate receptor neurotransmitter binding domains revealed by cryo-EM.
Int.J.Biol.Macromol., 149, 2020
6KSS
DownloadVisualize
BU of 6kss by Molmil
Rat GluD1 receptor(compact conformation) in complex with 7-CKA and Calcium ions
Descriptor: Glutamate receptor ionotropic, delta-1
Authors:Burada, A.P, Kumar, J.
Deposit date:2019-08-26
Release date:2020-01-15
Last modified:2020-01-29
Method:ELECTRON MICROSCOPY (8.1 Å)
Cite:Cryo-EM structures of the ionotropic glutamate receptor GluD1 reveal a non-swapped architecture.
Nat.Struct.Mol.Biol., 27, 2020
1IIT
DownloadVisualize
BU of 1iit by Molmil
GLUR0 LIGAND BINDING CORE COMPLEX WITH L-SERINE
Descriptor: SERINE, Slr1257 protein
Authors:Mayer, M.L, Olson, R, Gouaux, E.
Deposit date:2001-04-24
Release date:2001-09-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanisms for ligand binding to GluR0 ion channels: crystal structures of the glutamate and serine complexes and a closed apo state.
J.Mol.Biol., 311, 2001
1IIW
DownloadVisualize
BU of 1iiw by Molmil
GLUR0 LIGAND BINDING CORE: CLOSED-CLEFT LIGAND-FREE STRUCTURE
Descriptor: Slr1257 protein
Authors:Mayer, M.L, Olson, R, Gouaux, E.
Deposit date:2001-04-24
Release date:2001-09-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanisms for ligand binding to GluR0 ion channels: crystal structures of the glutamate and serine complexes and a closed apo state.
J.Mol.Biol., 311, 2001
2V3T
DownloadVisualize
BU of 2v3t by Molmil
Structure of the ligand-binding core of the ionotropic glutamate receptor-like GluRdelta2 in the apo form
Descriptor: CALCIUM ION, GLUTAMATE RECEPTOR DELTA-2 SUBUNIT SYNONYM GLURDELTA2, GLUR DELTA-2
Authors:Naur, P, Vestergaard, B, Gajhede, M, Kastrup, J.S.
Deposit date:2007-06-22
Release date:2007-08-07
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Ionotropic Glutamate-Like Receptor {Delta}2 Binds D-Serine and Glycine.
Proc.Natl.Acad.Sci.USA, 104, 2007
2WKY
DownloadVisualize
BU of 2wky by Molmil
Crystal structure of the ligand-binding core of GluR5 in complex with the agonist 4-AHCP
Descriptor: 3-(3-HYDROXY-7,8-DIHYDRO-6H-CYCLOHEPTA[D]ISOXAZOL-4-YL)-L-ALANINE, CHLORIDE ION, GLUTAMATE RECEPTOR, ...
Authors:Naur, P, Gajhede, M, Kastrup, J.S.
Deposit date:2009-06-18
Release date:2009-07-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Glutamate Receptor Glur5 Agonist (S)-2-Amino-3-(3-Hydroxy-7,8-Dihydro-6H-Cyclohepta[D]Isoxazol-4-Yl)Propionic Acid and the 8-Methyl Analogue: Synthesis, Molecular Pharmacology, and Biostructural Characterization
J.Med.Chem., 52, 2009
2UXA
DownloadVisualize
BU of 2uxa by Molmil
Crystal structure of the GluR2-flip ligand binding domain, r/g unedited.
Descriptor: GLUTAMATE RECEPTOR SUBUNIT GLUR2-FLIP, GLUTAMIC ACID, ZINC ION
Authors:Greger, I.H, Akamine, P, Khatri, L, Ziff, E.B.
Deposit date:2007-03-27
Release date:2007-04-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Developmentally Regulated, Combinatorial RNA Processing Modulates Ampa Receptor Biogenesis.
Neuron, 51, 2006
3B6T
DownloadVisualize
BU of 3b6t by Molmil
Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) T686A Mutant in Complex with Quisqualate at 2.1 Resolution
Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2, SULFATE ION
Authors:Cho, Y, Lolis, E, Howe, J.R.
Deposit date:2007-10-29
Release date:2008-02-05
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating.
J.Neurosci., 28, 2008

222624

PDB entries from 2024-07-17

PDB statisticsPDBj update infoContact PDBjnumon