7BQC
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![BU of 7bqc by Molmil](/molmil-images/mine/7bqc) | Solution NMR structure of NF4; de novo designed protein with a novel fold | Descriptor: | NF4 | Authors: | Kobayashi, N, Nagashima, T, Minami, S, Koga, R, Chikenji, T, Koga, N. | Deposit date: | 2020-03-24 | Release date: | 2021-03-24 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Exploration of novel alpha-beta-protein folds through de novo design Nat.Struct.Mol.Biol., 2023
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1QP6
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![BU of 1qp6 by Molmil](/molmil-images/mine/1qp6) | SOLUTION STRUCTURE OF ALPHA2D | Descriptor: | PROTEIN (ALPHA2D) | Authors: | Hill, R.B, DeGrado, W.F. | Deposit date: | 1999-06-01 | Release date: | 1999-06-09 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution Structure of Alpha2D, A Nativelike De Novo Designed Protein J.Am.Chem.Soc., 120, 1998
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7BQE
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![BU of 7bqe by Molmil](/molmil-images/mine/7bqe) | Solution NMR structure of NF3; de novo designed protein with a novel fold | Descriptor: | NF3 | Authors: | Kobayashi, N, Sugiki, T, Fujiwara, T, Minami, S, Koga, R, Chikenji, G, Koga, N. | Deposit date: | 2020-03-24 | Release date: | 2021-03-24 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Exploration of novel alpha-beta-protein folds through de novo design Nat.Struct.Mol.Biol., 2023
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8UGC
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![BU of 8ugc by Molmil](/molmil-images/mine/8ugc) | |
7BPL
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![BU of 7bpl by Molmil](/molmil-images/mine/7bpl) | Solution NMR structure of NF1; de novo designed protein with a novel fold | Descriptor: | NF1 | Authors: | Kobayashi, N, Sugiki, T, Fujiwara, T, Minami, S, Koga, R, Chikenji, G, Koga, N. | Deposit date: | 2020-03-23 | Release date: | 2021-03-24 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Exploration of novel alpha-beta-protein folds through de novo design Nat.Struct.Mol.Biol., 2023
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2K6R
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![BU of 2k6r by Molmil](/molmil-images/mine/2k6r) | Protein folding on a highly rugged landscape: Experimental observation of glassy dynamics and structural frustration | Descriptor: | Full Sequence Design 1 Synthetic Superstable | Authors: | Sadqi, M, de Alba, E, Perez-Jimenez, R, Sanchez-Ruiz, J.M, Munoz, V. | Deposit date: | 2008-07-18 | Release date: | 2009-06-16 | Last modified: | 2016-06-08 | Method: | SOLUTION NMR | Cite: | A designed protein as experimental model of primordial folding Proc.Natl.Acad.Sci.USA, 106, 2009
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3Q9N
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![BU of 3q9n by Molmil](/molmil-images/mine/3q9n) | In silico and in vitro co-evolution of a high affinity complementary protein-protein interface | Descriptor: | CARBAMOYL SARCOSINE, COENZYME A, CoA binding protein, ... | Authors: | Karanicolas, J, Corn, J.E, Chen, I, Joachimiak, L.A, Dym, O, Chung, S, Albeck, S, Unger, T, Hu, W, Liu, G, Delbecq, S, Montelione, G.T, Spiegel, C, Liu, D, Baker, D, Israel Structural Proteomics Center (ISPC) | Deposit date: | 2011-01-09 | Release date: | 2011-04-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A de novo protein binding pair by computational design and directed evolution. Mol.Cell, 42, 2011
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3Q9U
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![BU of 3q9u by Molmil](/molmil-images/mine/3q9u) | In silico and in vitro co-evolution of a high affinity complementary protein-protein interface | Descriptor: | COENZYME A, CoA binding protein, consensus ankyrin repeat | Authors: | Karanicolas, J, Corn, J.E, Chen, I, Joachimiak, L.A, Dym, O, Chung, S, Albeck, S, Unger, T, Hu, W, Liu, G, Delbecq, S, Montelione, G.T, Spiegel, C, Liu, D, Baker, D, Israel Structural Proteomics Center (ISPC) | Deposit date: | 2011-01-10 | Release date: | 2011-04-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A de novo protein binding pair by computational design and directed evolution. Mol.Cell, 42, 2011
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3QA9
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![BU of 3qa9 by Molmil](/molmil-images/mine/3qa9) | |
7A4Y
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![BU of 7a4y by Molmil](/molmil-images/mine/7a4y) | Crystal structure of the P5P6 coiled-coil in complex with nanobody Nb34. | Descriptor: | 1,2-ETHANEDIOL, Coiled-coil P5 peptide, Coiled-coil P6 peptide, ... | Authors: | Hadzi, S. | Deposit date: | 2020-08-20 | Release date: | 2021-05-05 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.157 Å) | Cite: | A nanobody toolbox targeting dimeric coiled-coil modules for functionalization of designed protein origami structures. Proc.Natl.Acad.Sci.USA, 118, 2021
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7A4T
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![BU of 7a4t by Molmil](/molmil-images/mine/7a4t) | Crystal structure of the GCN coiled-coil in complex with nanobody Nb39 | Descriptor: | 1,2-ETHANEDIOL, ACETYL GROUP, GCN4 isoform 1, ... | Authors: | Hadzi, S. | Deposit date: | 2020-08-20 | Release date: | 2021-05-05 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.124 Å) | Cite: | A nanobody toolbox targeting dimeric coiled-coil modules for functionalization of designed protein origami structures. Proc.Natl.Acad.Sci.USA, 118, 2021
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7A4D
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![BU of 7a4d by Molmil](/molmil-images/mine/7a4d) | |
7A50
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![BU of 7a50 by Molmil](/molmil-images/mine/7a50) | Crystal structure of the APH coiled-coil in complex with nanobody Nb26 | Descriptor: | 1,2-ETHANEDIOL, Coiled-coil APH, Nanobody Nb26 | Authors: | Hadzi, S. | Deposit date: | 2020-08-20 | Release date: | 2021-05-05 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.999 Å) | Cite: | A nanobody toolbox targeting dimeric coiled-coil modules for functionalization of designed protein origami structures. Proc.Natl.Acad.Sci.USA, 118, 2021
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7A48
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![BU of 7a48 by Molmil](/molmil-images/mine/7a48) | Crystal structure of the APH coiled-coil in complex with Nb49 | Descriptor: | APH colied-coil, Nanobody 49 | Authors: | Hadzi, S. | Deposit date: | 2020-08-19 | Release date: | 2021-05-05 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.547 Å) | Cite: | A nanobody toolbox targeting dimeric coiled-coil modules for functionalization of designed protein origami structures. Proc.Natl.Acad.Sci.USA, 118, 2021
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4ZV6
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![BU of 4zv6 by Molmil](/molmil-images/mine/4zv6) | Crystal structure of the artificial alpharep-7 octarellinV.1 complex | Descriptor: | AlphaRep-7, Octarellin V.1 | Authors: | Figueroa, M, Sleutel, M, Urvoas, A, Valerio-Lepiniec, M, Minard, P, Martial, J.A, van de Weerdt, C. | Deposit date: | 2015-05-18 | Release date: | 2016-05-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools. J.Struct.Biol., 195, 2016
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5BOP
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![BU of 5bop by Molmil](/molmil-images/mine/5bop) | Crystal structure of the artificial nanobody octarellinV.1 complex | Descriptor: | Nanobody, Octarellin V.1 | Authors: | Figueroa, M, Sleutel, M, Pardon, E, Steyaert, J, Martial, J.A, van de Weerdt, C. | Deposit date: | 2015-05-27 | Release date: | 2016-05-25 | Last modified: | 2016-06-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools. J.Struct.Biol., 195, 2016
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4QKS
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![BU of 4qks by Molmil](/molmil-images/mine/4qks) | Crystal Structure of 6xTrp/PV2: de novo designed beta-trefoil architecture with symmetric primary structure (L22W/L44W/L64W/L85W/L108W/L132W his Primitive Version 2) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DE NOVO PROTEIN 6XTRP/PV2, SULFATE ION | Authors: | Longo, L.M, Tenorio, C.A, Blaber, M. | Deposit date: | 2014-06-09 | Release date: | 2015-01-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A single aromatic core mutation converts a designed "primitive" protein from halophile to mesophile folding. Protein Sci., 24, 2015
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4DRT
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![BU of 4drt by Molmil](/molmil-images/mine/4drt) | Three dimensional structure of de novo designed serine hydrolase OSH26, Northeast Structural Genomics Consortium (NESG) target OR89 | Descriptor: | CHLORIDE ION, SODIUM ION, de novo designed serine hydrolase, ... | Authors: | Kuzin, A, Su, M, Rajagopalan, S, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Baker, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-02-17 | Release date: | 2012-04-18 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.002 Å) | Cite: | Design of activated serine-containing catalytic triads with atomic-level accuracy. Nat.Chem.Biol., 10, 2014
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2L69
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![BU of 2l69 by Molmil](/molmil-images/mine/2l69) | Solution NMR Structure of de novo designed protein, P-loop NTPase fold, Northeast Structural Genomics Consortium Target OR28 | Descriptor: | Rossmann 2x3 fold protein | Authors: | Liu, G, Koga, N, Koga, R, Xiao, R, Mao, A, Mao, B, Patel, D, Ciccosanti, C, Hamilton, K, Acton, T.B, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-11-17 | Release date: | 2011-01-12 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of de novo designed rossmann 2x3 fold protein, Northeast Structural Genomics Consortium Target OR28 To be Published
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2MN4
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![BU of 2mn4 by Molmil](/molmil-images/mine/2mn4) | NMR solution structure of a computational designed protein based on structure template 1cy5 | Descriptor: | Computational designed protein based on structure template 1cy5 | Authors: | Xiong, P, Wang, M, Zhang, J, Chen, Q, Liu, H. | Deposit date: | 2014-03-28 | Release date: | 2014-10-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Protein design with a comprehensive statistical energy function and boosted by experimental selection for foldability Nat Commun, 5, 2014
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2N41
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![BU of 2n41 by Molmil](/molmil-images/mine/2n41) | Solution NMR Structure of DE NOVO DESIGNED PROTEIN Top7NNSTYCC, Northeast Structural Genomics Consortium (NESG) Target OR34 | Descriptor: | OR34 | Authors: | Liu, G, Chan, K, Basanta, B, Xiao, R, Janjua, H, Kogan, S, Maglaqui, M, Ciccosanti, C, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2015-06-16 | Release date: | 2016-03-02 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution NMR Structure of DE NOVO DESIGNED PROTEIN Top7NNSTYCC, Northeast Structural Genomics Consortium (NESG) Target OR34 To be Published
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2N4E
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![BU of 2n4e by Molmil](/molmil-images/mine/2n4e) | Solution NMR Structure of DE NOVO DESIGNED PROTEIN Top7NNSTYCC, Northeast Structural Genomics Consortium (NESG) Target OR34 | Descriptor: | OR34 | Authors: | Liu, G, Chan, K, Basanta, B, Xiao, R, Janjua, H, Kogan, S, Maglaqui, M, Ciccosanti, C, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2015-06-17 | Release date: | 2015-12-09 | Method: | SOLUTION NMR | Cite: | Solution NMR Structure of DE NOVO DESIGNED PROTEIN Top7NNSTYCC, Northeast Structural Genomics Consortium (NESG) Target OR34 To be Published
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2N3Z
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![BU of 2n3z by Molmil](/molmil-images/mine/2n3z) | Solution NMR Structure of de novo designed protein, Rossmann2x2 Fold, Northeast Structural Genomics Consortium (NESG) Target OR446 | Descriptor: | OR446 | Authors: | Liu, G, Lin, Y, Koga, N, Koga, R, Xiao, R, Janjua, H, Pederson, K, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2015-06-15 | Release date: | 2015-09-16 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR Structure of DE NOVO DESIGNED PROTEIN, Rossmann2x2 Fold, Northeast Structural Genomics Consortium (NESG) Target OR446 To be Published
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2LR0
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![BU of 2lr0 by Molmil](/molmil-images/mine/2lr0) | Solution NMR structure of de novo designed protein, p-loop ntpase fold, northeast structural genomics consortium target or136 | Descriptor: | P-loop ntpase fold | Authors: | Liu, G, Koga, N, Koga, R, Xiao, R, Lee, H, Janjua, H, Kohan, E, Acton, T.B, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-03-19 | Release date: | 2012-07-04 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of de novo designed protein, p-loop ntpase fold, northeast structural genomics consortium target or136 To be Published
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4ZN8
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![BU of 4zn8 by Molmil](/molmil-images/mine/4zn8) | |