3Q9N

In silico and in vitro co-evolution of a high affinity complementary protein-protein interface

Summary for 3Q9N

• Entry DOI: 10.2210/pdb3q9n/pdb
• Related: 3Q9U
• Descriptor: CoA binding protein, consensus ankyrin repeat, CARBAMOYL SARCOSINE, ... (5 entities in total)
• Functional Keywords: structural genomics, israel structural proteomics center, ispc, prb-binding designed ankyrin repeat, protein binding, de novo protein
• Biological source: Escherichia coli; More
• Total number of polymer chains: 4
• Total formula weight: 67119.47

Authors

Karanicolas, J.,Corn, J.E.,Chen, I.,Joachimiak, L.A.,Dym, O.,Chung, S.,Albeck, S.,Unger, T.,Hu, W.,Liu, G.,Delbecq, S.,Montelione, G.T.,Spiegel, C.,Liu, D.,Baker, D.,Israel Structural Proteomics Center (ISPC) (deposition date: 2011-01-09, release date: 2011-04-27, Last modification date: 2023-09-13)

• Primary citation: Karanicolas, J.,Corn, J.E.,Chen, I.,Joachimiak, L.A.,Dym, O.,Peck, S.H.,Albeck, S.,Unger, T.,Hu, W.,Liu, G.,Delbecq, S.,Montelione, G.T.,Spiegel, C.P.,Liu, D.R.,Baker, D.; A de novo protein binding pair by computational design and directed evolution.; Mol.Cell, 42:250-260, 2011; PubMed: 21458342; DOI: 10.1016/j.molcel.2011.03.010

Experimental method

X-RAY DIFFRACTION (2 Å)