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4QKS

Crystal Structure of 6xTrp/PV2: de novo designed beta-trefoil architecture with symmetric primary structure (L22W/L44W/L64W/L85W/L108W/L132W his Primitive Version 2)

Summary for 4QKS
Entry DOI10.2210/pdb4qks/pdb
Related4D8H 4QKR
DescriptorDE NOVO PROTEIN 6XTRP/PV2, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, ... (4 entities in total)
Functional Keywordssimplified protein design, prebiotic protein, beta-trefoil, de novo protein
Biological sourceSynthetic
Total number of polymer chains1
Total formula weight14979.07
Authors
Longo, L.M.,Tenorio, C.A.,Blaber, M. (deposition date: 2014-06-09, release date: 2015-01-14, Last modification date: 2024-02-28)
Primary citationLongo, L.M.,Tenorio, C.A.,Kumru, O.S.,Middaugh, C.R.,Blaber, M.
A single aromatic core mutation converts a designed "primitive" protein from halophile to mesophile folding.
Protein Sci., 24:27-37, 2015
Cited by
PubMed: 25297559
DOI: 10.1002/pro.2580
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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