PDB: 453 件ウェブページステータス検索Chemie searchBIRD

---

2DC9	X-ray crystal structure analysis of bovine spleen cathepsin B-CA074Me complex 分子名称: CATHEPSIN B, GLYCEROL, METHYL N-({(2S,3S)-3-[(PROPYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE, ... 著者 Watanabe, D. 登録日 2005-12-31 公開日 2006-01-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes To be Published
2DC8	X-ray crystal structure analysis of bovine spleen cathepsin B-CA059 complex 分子名称: CATHEPSIN B, GLYCEROL, N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCINE, ... 著者 Watanabe, D. 登録日 2005-12-31 公開日 2006-01-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes To be Published
2DC7	X-ray crystal structure analysis of bovine spleen cathepsin B-CA042 complex 分子名称: CATHEPSIN B, GLYCEROL, N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-THREONYL-L-ISOLEUCINE, ... 著者 Watanabe, D. 登録日 2005-12-31 公開日 2006-01-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes To be Published
2DC6	X-ray crystal structure analysis of bovine spleen cathepsin B-CA073 complex 分子名称: BENZYL N-({(2S,3S)-3-[(PROPYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE, GLYCEROL, PHOSPHATE ION, ... 著者 Watanabe, D. 登録日 2005-12-28 公開日 2006-01-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes To be Published
2CIO	The high resolution x-ray structure of papain complexed with fragments of the Trypanosoma brucei cysteine protease inhibitor ICP. 分子名称: ACETATE ION, GLYCEROL, INHIBITOR OF CYSTEINE PEPTIDASE, ... 著者 Alphey, M.S, Hunter, W.N. 登録日 2006-03-24 公開日 2006-05-18 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 High-Resolution Complex of Papain with Remnants of a Cysteine Protease Inhibitor Derived from Trypanosoma Brucei Acta Crystallogr.,Sect.F, 62, 2006
2C0Y	THE CRYSTAL STRUCTURE OF A CYS25ALA MUTANT OF HUMAN PROCATHEPSIN S 分子名称: PROCATHEPSIN S 著者 Kaulmann, G, Palm, G.J, Schilling, K, Hilgenfeld, R, Wiederanders, B. 登録日 2005-09-08 公開日 2006-11-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Crystal Structure of a Cys25 -> Ala Mutant of Human Procathepsin S Elucidates Enzyme-Prosequence Interactions. Protein Sci., 15, 2006
2BDZ	Mexicain from Jacaratia mexicana 分子名称: Mexicain, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE 著者 Gavira, J.A, Oliver-Salvador, M.C, Gonzalez-Ramirez, L.A, Soriano-Garcia, M, Garcia-Ruiz, J.M. 登録日 2005-10-21 公開日 2006-10-03 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystallographic structure of Mexicain from Jacaratia mexicana To be Published
2BDL	Cathepsin K complexed with a pyrrolidine ketoamide-based inhibitor 分子名称: (3S)-1-{[(3,5-DIMETHYLISOXAZOL-4-YL)AMINO]CARBONYL}-4,4-DIMETHYLPYRROLIDIN-3-YL{(1S)-1-[1-HYDROXY-2-OXO-2-{[(1R)-1-PHENYLETHYL]AMINO}ETHYL]PENTYL}CARBAMATE, Cathepsin K 著者 Shewchuk, L.M. 登録日 2005-10-20 公開日 2006-03-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Novel, potent P2-P3 pyrrolidine derivatives of ketoamide-based cathepsin K inhibitors. Bioorg.Med.Chem.Lett., 16, 2006
2B1N	Crystal structure of a papain-fold protein without the catalytic cysteine from seeds of Pachyrhizus erosus 分子名称: SPE31, alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, peptide (LYS)(ALA)(SER)(VAL)(GLY) 著者 Zhang, M, Wei, Z, Chang, S. 登録日 2005-09-16 公開日 2006-10-03 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of a papain-fold protein without the catalytic residue: a novel member in the cysteine proteinase family J.Mol.Biol., 358, 2006
2B1M	Crystal structure of a papain-fold protein without the catalytic cysteine from seeds of Pachyrhizus erosus 分子名称: DI(HYDROXYETHYL)ETHER, SPE31, TETRAETHYLENE GLYCOL, ... 著者 Zhang, M, Wei, Z, Chang, S. 登録日 2005-09-16 公開日 2006-10-03 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of a papain-fold protein without the catalytic residue: a novel member in the cysteine proteinase family J.Mol.Biol., 358, 2006
2AUZ	Cathepsin K complexed with a semicarbazone inhibitor 分子名称: 1-(PHENYLMETHYL)CYCLOPENTYL[(1S)-1-FORMYLPENTYL]CARBAMATE, Cathepsin K, SULFATE ION 著者 Adkison, K.K, Barrett, D.G, Deaton, D.N, Gampe, R.T, Hassell, A.M, Long, S.T, McFadyen, R.B, Miller, A.B, Miller, L.R, Shewchuk, L.M. 登録日 2005-08-29 公開日 2006-08-08 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Semicarbazone-based inhibitors of cathepsin K, are they prodrugs for aldehyde inhibitors? Bioorg.Med.Chem.Lett., 16, 2006
2AUX	Cathepsin K complexed with a semicarbazone inhibitor 分子名称: (1R)-2-METHYL-1-(PHENYLMETHYL)PROPYL[(1S)-1-FORMYLPENTYL]CARBAMATE, Cathepsin K 著者 Adkison, K.K, Barrett, D.G, Deaton, D.N, Gampe, R.T, Hassell, A.M, Long, S.T, McFadyen, R.B, Miller, A.B, Miller, L.R, Shewchuk, L.M. 登録日 2005-08-29 公開日 2006-08-08 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Semicarbazone-based inhibitors of cathepsin K, are they prodrugs for aldehyde inhibitors? Bioorg.Med.Chem.Lett., 16, 2006
2ATO	Crystal structure of Human Cathepsin K in complex with myocrisin 分子名称: (S)-(1,2-DICARBOXYETHYLTHIO)GOLD, Cathepsin K, SULFATE ION 著者 Weidauer, E, Yasuda, Y, Biswal, B.K, Kerr, L.D, Cherney, M.M, Gordon, R.E, James, M.N.G, Bromme, D. 登録日 2005-08-25 公開日 2006-08-29 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Effects of disease-modifying anti-rheumatic drugs (DMARDs) on the activities of rheumatoid arthritis-associated cathepsins K and S. Biol.Chem., 388, 2007
2AS8	Crystal structure of mature and fully active Der p 1 allergen 分子名称: MAGNESIUM ION, Major mite fecal allergen Der p 1 著者 de Halleux, S, Stura, E, VanderElst, L, Carlier, V, Jacquemin, M, Saint-Remy, J.-M. 登録日 2005-08-23 公開日 2005-12-06 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Three-dimensional structure and IgE-binding properties of mature fully active Der p 1, a clinically relevant major allergen J.Allergy Clin.Immunol., 117, 2006
2AIM	CRUZAIN INHIBITED WITH BENZOYL-ARGININE-ALANINE-FLUOROMETHYLKETONE 分子名称: BENZOYL-ARGININE-ALANINE-FLUORO-METHYL KETONE, CRUZAIN 著者 Gillmor, S.A, Fletterick, R.J. 登録日 1997-04-21 公開日 1997-10-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural determinants of specificity in the cysteine protease cruzain. Protein Sci., 6, 1997
2ACT	CRYSTALLOGRAPHIC REFINEMENT OF THE STRUCTURE OF ACTINIDIN AT 1.7 ANGSTROMS RESOLUTION BY FAST FOURIER LEAST-SQUARES METHODS 分子名称: ACTINIDIN PRECURSOR, AMMONIUM ION 著者 Baker, E.N. 登録日 1979-11-27 公開日 1980-03-07 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystallographic Refinement of the Structure of Actinidin at 1.7 Angstroms Resolution by Fast Fourier Least-Squares Methods Acta Crystallogr.,Sect.A, 36, 1980
1YVB	the Plasmodium falciparum Cysteine Protease Falcipain-2 分子名称: Cystatin, GLYCEROL, falcipain 2 著者 Wang, S.X. 登録日 2005-02-15 公開日 2006-03-28 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for unique mechanisms of folding and hemoglobin binding by a malarial protease. Proc.Natl.Acad.Sci.Usa, 103, 2006
1YT7	Cathepsin K complexed with a constrained ketoamide inhibitor 分子名称: (1R)-2,2-DIMETHYL-1-({5-[4-(TRIFLUOROMETHYL)PHENYL]-1,3,4-OXADIAZOL-2-YL}METHYL)PROPYL (1S)-1-{OXO[(2-OXO-1,3-OXAZOLIDIN-3-YL)AMINO]ACETYL}PENTYLCARBAMATE, Cathepsin K, SULFATE ION 著者 Barrett, D.G, Boncek, V.M, Catalano, J.G, Deaton, D.N, Hassell, A.M, Jurgensen, C.H, Long, S.T, McFadyen, R.B, Miller, A.B, Miller, L.R, Payne, J.A, Ray, J.A, Samano, V, Shewchuk, L.M, Tavares, F.X, Wells-Knecht, K.J, Willard, D.H, Wright, L.L, Zhou, H.Q. 登録日 2005-02-10 公開日 2005-07-19 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 P(2)-P(3) conformationally constrained ketoamide-based inhibitors of cathepsin K. Bioorg.Med.Chem.Lett., 15, 2005
1YK8	Cathepsin K complexed with a cyanamide-based inhibitor 分子名称: Cathepsin K, TERT-BUTYL 2-CYANO-2-METHYLHYDRAZINECARBOXYLATE 著者 Barrett, D.G, Deaton, D.N, Hassell, A.M, McFadyen, R.B, Miller, A.B, Miller, L.R, Payne, J.A, Shewchuk, L.M, Willard, D.H, Wright, L.L. 登録日 2005-01-17 公開日 2005-07-19 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Acyclic cyanamide-based inhibitors of cathepsin K. Bioorg.Med.Chem.Lett., 15, 2005
1YK7	Cathepsin K complexed with a cyanopyrrolidine inhibitor 分子名称: Cathepsin K, N2-[(BENZYLOXY)CARBONYL]-N1-[(3S)-1-CYANOPYRROLIDIN-3-YL]-L-LEUCINAMIDE 著者 Barrett, D.G, Deaton, D.N, Hassell, A.M, McFadyen, R.B, Miller, A.B, Miller, L.R, Shewchuk, L.M, Tavares, F.X, Willard, D.H, Wright, L.L. 登録日 2005-01-17 公開日 2005-03-22 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Novel and potent cyclic cyanamide-based cathepsin K inhibitors. Bioorg.Med.Chem.Lett., 15, 2005
1YAL	CARICA PAPAYA CHYMOPAPAIN AT 1.7 ANGSTROMS RESOLUTION 分子名称: CHYMOPAPAIN 著者 Maes, D, Bouckaert, J, Poortmans, F, Wyns, L, Looze, Y. 登録日 1996-06-20 公開日 1996-12-23 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure of chymopapain at 1.7 A resolution. Biochemistry, 35, 1996
1XKG	Crystal structure of the major house dust mite allergen Der p 1 in its pro form at 1.61 A resolution 分子名称: GLYCEROL, Major mite fecal allergen Der p 1, SULFATE ION, ... 著者 Meno, K, Thorsted, P.B, Gajhede, M. 登録日 2004-09-29 公開日 2005-06-28 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 The crystal structure of recombinant proDer p 1, a major house dust mite proteolytic allergen. J.Immunol., 175, 2005
1VSN	Crystal structure of a potent small molecule inhibitor bound to cathepsin K 分子名称: Cathepsin K, N-(2-AMINOETHYL)-N~2~-{(1S)-1-[4'-(AMINOSULFONYL)BIPHENYL-4-YL]-2,2,2-TRIFLUOROETHYL}-L-LEUCINAMIDE 著者 McGrath, M. 登録日 2007-03-19 公開日 2007-04-24 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Identification of a potent and selective non-basic cathepsin K inhibitor. Bioorg.Med.Chem.Lett., 16, 2006
1U9X	Crystal Structure of the Cysteine Protease Human Cathepsin K in Complex with the Covalent Inhibitor NVP-ABJ688 分子名称: 9-CYCLOPENTYL-6-{2-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPOXY]-PHENYLAMINO}-9H-PURINE-2-CARBONITRILE, Cathepsin K 著者 Cowan-Jacob, S.W. 登録日 2004-08-11 公開日 2005-08-11 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Novel purine nitrile derived inhibitors of the cysteine protease cathepsin K J.Med.Chem., 47, 2004
1U9W	Crystal Structure of the Cysteine Protease Human Cathepsin K in Complex with the Covalent Inhibitor NVP-ABI491 分子名称: 9-CYCLOPENTYL-6-[2-(3-IMIDAZOL-1-YL-PROPOXY)-PHENYLAMINO]-9H-PURINE-2-CARBONITRILE, Cathepsin K 著者 Cowan-Jacob, S.W. 登録日 2004-08-11 公開日 2005-08-11 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Novel purine nitrile derived inhibitors of the cysteine protease cathepsin K J.Med.Chem., 47, 2004

<45678910111213141516171819>