PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

Crystal structure of a potent small molecule inhibitor bound to cathepsin K
Descriptor:	Cathepsin K, N-(2-AMINOETHYL)-N~2~-{(1S)-1-[4'-(AMINOSULFONYL)BIPHENYL-4-YL]-2,2,2-TRIFLUOROETHYL}-L-LEUCINAMIDE
Authors:	McGrath, M.
Deposit date:	2007-03-19
Release date:	2007-04-24
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Identification of a potent and selective non-basic cathepsin K inhibitor. Bioorg.Med.Chem.Lett., 16, 2006

Selective PI3K beta inhibitor bound to PI3K delta
Descriptor:	4-[1-(5,8-difluoroquinolin-4-yl)-2-methyl-4-(4H-1,2,4-triazol-3-yl)-1H-benzimidazol-6-yl]-3-fluoropyridin-2-amine, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Authors:	Somoza, J, Villasenor, A, McGrath, M.
Deposit date:	2018-05-18
Release date:	2018-08-01
Last modified:	2024-03-13
Method:	X-RAY DIFFRACTION (2.601 Å)
Cite:	Atropisomerism by Design: Discovery of a Selective and Stable Phosphoinositide 3-Kinase (PI3K) beta Inhibitor. J. Med. Chem., 61, 2018