2AS8

Crystal structure of mature and fully active Der p 1 allergen

Summary for 2AS8

Entry DOI	10.2210/pdb2as8/pdb
Descriptor	Major mite fecal allergen Der p 1, MAGNESIUM ION (3 entities in total)
Functional Keywords	cysteine proteinase fold, hydrolase
Biological source	Dermatophagoides pteronyssinus (European house dust mite)
Cellular location	Secreted: P08176
Total number of polymer chains	2
Total formula weight	50106.27
Authors	de Halleux, S.,Stura, E.,VanderElst, L.,Carlier, V.,Jacquemin, M.,Saint-Remy, J.-M. (deposition date: 2005-08-23, release date: 2005-12-06, Last modification date: 2023-10-25)
Primary citation	de Halleux, S.,Stura, E.,VanderElst, L.,Carlier, V.,Jacquemin, M.,Saint-Remy, J.-M. Three-dimensional structure and IgE-binding properties of mature fully active Der p 1, a clinically relevant major allergen J.Allergy Clin.Immunol., 117:571-576, 2006 Cited by PubMed: 16522455 DOI: 10.1016/j.jaci.2005.11.032 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation