2AS8

Crystal structure of mature and fully active Der p 1 allergen

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Major mite fecal allergen Der p 1	polymer	222	25028.8	2	UniProt (P08176) Pfam (PF00112)	Dermatophagoides pteronyssinus (European house dust mite)	Der p I
2	C, D (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	E, F (A, B)	water	water		18.0	791	Chemie (HOH)

Sequence modifications

A, B: 1 - 222 (UniProt: P08176)

PDB	External Database	Details
Gln 52	Asn 150	engineered mutation
Ala 124	Val 222	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	50057.7
Non-Polymers*	Number of molecules	2
	Total formula weight	48.6
All*	Total formula weight	50106.3

*Water molecules are not included.