2ATO

Crystal structure of Human Cathepsin K in complex with myocrisin

Summary for 2ATO

Entry DOI	10.2210/pdb2ato/pdb
Descriptor	Cathepsin K, SULFATE ION, (S)-(1,2-DICARBOXYETHYLTHIO)GOLD, ... (4 entities in total)
Functional Keywords	cathepsin k, myocrysin, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Lysosome: P43235
Total number of polymer chains	1
Total formula weight	23965.65
Authors	Weidauer, E.,Yasuda, Y.,Biswal, B.K.,Kerr, L.D.,Cherney, M.M.,Gordon, R.E.,James, M.N.G.,Bromme, D. (deposition date: 2005-08-25, release date: 2006-08-29, Last modification date: 2023-08-23)
Primary citation	Weidauer, E.,Yasuda, Y.,Biswal, B.K.,Cherny, M.,James, M.N.,Bromme, D. Effects of disease-modifying anti-rheumatic drugs (DMARDs) on the activities of rheumatoid arthritis-associated cathepsins K and S. Biol.Chem., 388:331-336, 2007 Cited by PubMed: 17338641 DOI: 10.1515/BC.2007.037 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation