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4WMF
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BU of 4wmf by Molmil
Crystal structure of catalytically inactive MERS-CoV 3CL protease (C148A) in spacegroup P212121
Descriptor: DI(HYDROXYETHYL)ETHER, MERS-CoV 3CL protease, TETRAETHYLENE GLYCOL
Authors:Lountos, G.T, Needle, D, Waugh, D.S.
Deposit date:2014-10-08
Release date:2015-05-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structures of the Middle East respiratory syndrome coronavirus 3C-like protease reveal insights into substrate specificity.
Acta Crystallogr.,Sect.D, 71, 2015
4WMD
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BU of 4wmd by Molmil
Crystal structure of catalytically inactive MERS-CoV 3CL protease (C148A) in spacegroup C2221
Descriptor: DI(HYDROXYETHYL)ETHER, ORF1a, PENTAETHYLENE GLYCOL, ...
Authors:Lountos, G.T, Needle, D, Waugh, D.S.
Deposit date:2014-10-08
Release date:2015-05-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.585 Å)
Cite:Structures of the Middle East respiratory syndrome coronavirus 3C-like protease reveal insights into substrate specificity.
Acta Crystallogr.,Sect.D, 71, 2015
7OVT
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BU of 7ovt by Molmil
major seeded in vitro fibril morphology from murine SAA1.1 protein
Descriptor: Serum amyloid A-2 protein
Authors:Heerde, T, Schmidt, M, Faendrich, M.
Deposit date:2021-06-15
Release date:2022-02-02
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Cryo-EM demonstrates the in vitro proliferation of an ex vivo amyloid fibril morphology by seeding.
Nat Commun, 13, 2022
6OFH
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BU of 6ofh by Molmil
Structure of Salmonella type III secretion system needle filament
Descriptor: Protein PrgI
Authors:Guo, E.Z, Galan, J.E.
Deposit date:2019-03-29
Release date:2019-07-10
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:A polymorphic helix of a Salmonella needle protein relays signals defining distinct steps in type III secretion.
Plos Biol., 17, 2019
6OFE
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BU of 6ofe by Molmil
Helical reconstruction of Type III Secretion System Needle filament mutant-PrgI S49A
Descriptor: Protein PrgI
Authors:Guo, E.Z, Galan, J.E.
Deposit date:2019-03-29
Release date:2019-07-10
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.61 Å)
Cite:A polymorphic helix of a Salmonella needle protein relays signals defining distinct steps in type III secretion.
Plos Biol., 17, 2019
6OFF
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BU of 6off by Molmil
High-resolution filamentous structures of in vitro polymerized PrgI needle
Descriptor: Protein PrgI
Authors:Guo, E.Z, Galan, J.E.
Deposit date:2019-03-29
Release date:2019-07-10
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:A polymorphic helix of a Salmonella needle protein relays signals defining distinct steps in type III secretion.
Plos Biol., 17, 2019
4WME
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BU of 4wme by Molmil
Crystal structure of catalytically inactive MERS-CoV 3CL Protease (C148A) in spacegroup C2
Descriptor: 1,2-ETHANEDIOL, MERS-CoV 3CL protease
Authors:Lountos, G.T, Needle, D, Waugh, D.S.
Deposit date:2014-10-08
Release date:2015-05-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structures of the Middle East respiratory syndrome coronavirus 3C-like protease reveal insights into substrate specificity.
Acta Crystallogr.,Sect.D, 71, 2015
6PEP
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BU of 6pep by Molmil
Focussed refinement of InvGN0N1:SpaPQR:PrgIJ from the Salmonella SPI-1 injectisome needle complex
Descriptor: Protein InvG, Protein PrgH, Protein PrgI, ...
Authors:Hu, J, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2019-06-20
Release date:2019-10-23
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
2CA5
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BU of 2ca5 by Molmil
MxiH needle protein of Shigella Flexneri (monomeric form, residues 1- 78)
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, MXIH, ...
Authors:Deane, J.E, Roversi, P, Cordes, F.S, Johnson, S, Kenjale, R, Picking, W.L, Picking, W.D, Blocker, A.J, Lea, S.M.
Deposit date:2005-12-16
Release date:2006-08-07
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular Model of a Type III Secretion System Needle: Implications for Host-Cell Sensing
Proc.Natl.Acad.Sci.USA, 103, 2006
8ORF
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BU of 8orf by Molmil
Cryo-EM structure of SH-SY5Y seeded with filaments from corticobasal degeneration extracts
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-13
Release date:2023-04-26
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration.
Febs Open Bio, 13, 2023
8ORG
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BU of 8org by Molmil
Cryo-EM structure of SH-SY5Y seeded with filaments from corticobasal degeneration extracts (Type II)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-13
Release date:2023-04-26
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration.
Febs Open Bio, 13, 2023
8ORE
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BU of 8ore by Molmil
Cryo-EM structure of SH-SY5Y seeded with filaments from Alzheimer's Disease
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-13
Release date:2023-04-26
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration.
Febs Open Bio, 13, 2023
2CI2
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BU of 2ci2 by Molmil
CRYSTAL AND MOLECULAR STRUCTURE OF THE SERINE PROTEINASE INHIBITOR CI-2 FROM BARLEY SEEDS
Descriptor: CHYMOTRYPSIN INHIBITOR 2
Authors:Mcphalen, C.A, James, M.N.G.
Deposit date:1988-09-05
Release date:1988-09-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal and molecular structure of the serine proteinase inhibitor CI-2 from barley seeds.
Biochemistry, 26, 1987
9CGZ
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BU of 9cgz by Molmil
Alzheimer's Disease Seeded Mixed 0N4R and 0N3R Tau Fibrils
Descriptor: Isoform Fetal-tau of Microtubule-associated protein tau
Authors:Duan, P, Dregni, A.J, Xu, H, Changolkar, L, Lee, V.M.-Y, Hong, M.
Deposit date:2024-07-01
Release date:2024-09-11
Last modified:2024-10-02
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Alzheimer's disease seeded tau forms paired helical filaments yet lacks seeding potential.
J.Biol.Chem., 300, 2024
9CGX
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BU of 9cgx by Molmil
Alzheimer's Disease Seeded 0N3R Tau Fibrils
Descriptor: Isoform Fetal-tau of Microtubule-associated protein tau
Authors:Duan, P, Dregni, A.J, Xu, H, Changolkar, L, Lee, V.M.-Y, Hong, M.
Deposit date:2024-07-01
Release date:2024-09-11
Last modified:2024-10-02
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Alzheimer's disease seeded tau forms paired helical filaments yet lacks seeding potential.
J.Biol.Chem., 300, 2024
7RYE
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BU of 7rye by Molmil
Cryo-EM structure of the needle filament-tip complex of the Salmonella type III secretion injectisome
Descriptor: Cell invasion protein SipD, Protein PrgI
Authors:Guo, E.Z, Galan, J.E.
Deposit date:2021-08-25
Release date:2021-11-10
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structure of the needle filament tip complex of the Salmonella type III secretion injectisome.
Proc.Natl.Acad.Sci.USA, 118, 2021
6ZNI
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BU of 6zni by Molmil
Structure of the Shigella MxiH needle filament attached to the basal body
Descriptor: Protein MxiH
Authors:Lunelli, M, Kotov, V, Marlovits, T.C, Kolbe, M.
Deposit date:2020-07-06
Release date:2021-07-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Helical reconstruction of Salmonella and Shigella needle filaments attached to type 3 basal bodies.
Biochem Biophys Rep, 27, 2021
6ZNH
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BU of 6znh by Molmil
Structure of the Salmonella PrgI needle filament attached to the basal body
Descriptor: PrgI
Authors:Lunelli, M, Kotov, V, Wald, J, Kolbe, M, Marlovits, T.C.
Deposit date:2020-07-06
Release date:2021-07-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Helical reconstruction of Salmonella and Shigella needle filaments attached to type 3 basal bodies.
Biochem Biophys Rep, 27, 2021
6N4O
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BU of 6n4o by Molmil
Human Argonaute2-miR-122 bound to a seed and supplementary paired target
Descriptor: Protein argonaute-2, RNA (5'-R(*CP*CP*AP*UP*UP*GP*UP*CP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3')
Authors:Sheu-Gruttadauria, J, MacRae, I.J.
Deposit date:2018-11-19
Release date:2019-05-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.899 Å)
Cite:Beyond the seed: structural basis for supplementary microRNA targeting by human Argonaute2.
Embo J., 38, 2019
2BAA
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BU of 2baa by Molmil
THE REFINED CRYSTAL STRUCTURE OF AN ENDOCHITINASE FROM HORDEUM VULGARE L. SEEDS TO 1.8 ANGSTROMS RESOLUTION
Descriptor: ENDOCHITINASE (26 KD)
Authors:Hart, P.J, Pfluger, H.D, Monzingo, A.F, Ready, M.P, Ernst, S.R, Hollis, T, Robertus, J.D.
Deposit date:1995-01-26
Release date:1996-01-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The refined crystal structure of an endochitinase from Hordeum vulgare L. seeds at 1.8 A resolution.
J.Mol.Biol., 248, 1995
1CTI
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BU of 1cti by Molmil
DETERMINATION OF THE COMPLETE THREE-DIMENSIONAL STRUCTURE OF THE TRYPSIN INHIBITOR FROM SQUASH SEEDS IN AQUEOUS SOLUTION BY NUCLEAR MAGNETIC RESONANCE AND A COMBINATION OF DISTANCE GEOMETRY AND DYNAMICAL SIMULATED ANNEALING
Descriptor: TRYPSIN INHIBITOR
Authors:Holak, T.A, Gondol, D, Otlewski, J, Wilusz, T.
Deposit date:1990-08-28
Release date:1992-01-15
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Determination of the complete three-dimensional structure of the trypsin inhibitor from squash seeds in aqueous solution by nuclear magnetic resonance and a combination of distance geometry and dynamical simulated annealing.
J.Mol.Biol., 210, 1989
3J0R
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BU of 3j0r by Molmil
Model of a type III secretion system needle based on a 7 Angstrom resolution cryoEM map
Descriptor: Protein mxiH
Authors:Fujii, T, Cheung, M, Blanco, A, Kato, T, Blocker, A.J, Namba, K.
Deposit date:2011-11-03
Release date:2012-02-29
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Structure of a type III secretion needle at 7-A resolution provides insights into its assembly and signaling mechanisms.
Proc.Natl.Acad.Sci.USA, 109, 2012
2V6L
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BU of 2v6l by Molmil
Molecular Model of a Type III Secretion System Needle
Descriptor: MXIH
Authors:Deane, J.E, Roversi, P, Cordes, F.S, Johnson, S, Kenjale, R, Daniell, S, Booy, F, Picking, W.L, Picking, W.D, Blocker, A.J, Lea, S.M.
Deposit date:2007-07-19
Release date:2007-07-31
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (16 Å)
Cite:Molecular model of a type III secretion system needle: Implications for host-cell sensing.
Proc. Natl. Acad. Sci. U.S.A., 103, 2006
3BBG
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BU of 3bbg by Molmil
MULTI-CONFORMER STRUCTURE OF RAGWEED POLLEN ALLERGEN FROM AMBROSIA TRIFIDA V, NMR, 2 STRUCTURES
Descriptor: POLLEN ALLERGEN 5
Authors:Warren, G.L, Tuner, C.J, Petsko, G.A, Brunger, A.T.
Deposit date:1998-04-24
Release date:1998-06-17
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:A Highly Precise Solution 1H NMR Structure of Ragweed Allergen Amb. T. V
To be Published
2CMY
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BU of 2cmy by Molmil
Crystal complex between bovine trypsin and Veronica hederifolia trypsin inhibitor
Descriptor: CALCIUM ION, CATIONIC TRYPSIN, GLYCEROL, ...
Authors:Conners, R, Yardley, J.L, Konarev, A, Shewry, P, Brady, R.L.
Deposit date:2006-05-16
Release date:2007-05-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:An Unusual Helix-Turn-Helix Protease Inhibitory Motif in a Novel Trypsin Inhibitor from Seeds of Veronica (Veronica Hederifolia L.).
J.Biol.Chem., 282, 2007

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