4WME
Crystal structure of catalytically inactive MERS-CoV 3CL Protease (C148A) in spacegroup C2
Summary for 4WME
| Entry DOI | 10.2210/pdb4wme/pdb |
| Related | 4WMD 4WMF |
| Descriptor | MERS-CoV 3CL protease, 1,2-ETHANEDIOL (3 entities in total) |
| Functional Keywords | mers, coronavirus, 3cl protease, hydrolase |
| Biological source | Middle East respiratory syndrome coronavirus |
| Cellular location | Host cytoplasm, host perinuclear region . Host membrane ; Multi-pass membrane protein : W6A941 |
| Total number of polymer chains | 4 |
| Total formula weight | 134405.66 |
| Authors | Lountos, G.T.,Needle, D.,Waugh, D.S. (deposition date: 2014-10-08, release date: 2015-05-13, Last modification date: 2023-09-27) |
| Primary citation | Needle, D.,Lountos, G.T.,Waugh, D.S. Structures of the Middle East respiratory syndrome coronavirus 3C-like protease reveal insights into substrate specificity. Acta Crystallogr.,Sect.D, 71:1102-1111, 2015 Cited by PubMed: 25945576DOI: 10.1107/S1399004715003521 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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