4WME
Crystal structure of catalytically inactive MERS-CoV 3CL Protease (C148A) in spacegroup C2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | MERS-CoV 3CL protease | polymer | 306 | 33322.1 | 4 | UniProt (W6A941) Pfam (PF05409) In PDB | Middle East respiratory syndrome coronavirus | |
| 2 | A, B, C, D | 1,2-ETHANEDIOL | non-polymer | 62.1 | 18 | Chemie (EDO) | |||
| 3 | water | water | 18.0 | 1638 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 306 (UniProt: W6A941)
| PDB | External Database | Details |
|---|---|---|
| Ala 148 | Cys 3395 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 133288.4 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 1117.2 | |
| All* | Total formula weight | 134405.7 |
