4WME

Crystal structure of catalytically inactive MERS-CoV 3CL Protease (C148A) in spacegroup C2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	MERS-CoV 3CL protease	polymer	306	33322.1	4	UniProt (W6A941) Pfam (PF05409)	Middle East respiratory syndrome coronavirus
2	E, F, G, H, I... (A, B, C, D)	1,2-ETHANEDIOL	non-polymer		62.1	18	Chemie (EDO)
3	W, X, Y, Z (A, B, C, D)	water	water		18.0	1638	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 306 (UniProt: W6A941)

PDB	External Database	Details
Ala 148	Cys 3395	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	133288.4
Non-Polymers*	Number of molecules	18
	Total formula weight	1117.2
All*	Total formula weight	134405.7

*Water molecules are not included.