Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 401 |
| Chain | Residue |
| A | PHE222 |
| A | LYS224 |
| A | GLN271 |
| A | GLN277 |
| A | HOH596 |
| A | HOH704 |
| A | HOH740 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 402 |
| Chain | Residue |
| A | TRP221 |
| A | HOH697 |
| A | HOH812 |
| A | HOH847 |
| A | GLY218 |
| A | ALA220 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 403 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | GLU169 |
| A | ALA171 |
| A | HOH745 |
| A | HOH858 |
| A | HOH1029 |
| D | MET253 |
| D | GLY302 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 405 |
| Chain | Residue |
| A | GLN69 |
| A | LYS70 |
| A | HIS71 |
| A | ILE72 |
| A | ASN122 |
| A | GLY123 |
| A | HOH508 |
| A | HOH679 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 406 |
| Chain | Residue |
| A | TYR137 |
| A | GLY186 |
| A | ALA187 |
| A | HOH639 |
| A | HOH700 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 407 |
| Chain | Residue |
| A | CYS219 |
| A | GLN280 |
| A | LEU282 |
| A | GLY283 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for residue EDO B 401 |
| Chain | Residue |
| A | LYS5 |
| A | MET6 |
| A | SER7 |
| A | THR128 |
| B | LYS5 |
| B | SER7 |
| B | PHE129 |
| B | THR130 |
| B | HOH566 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | binding site for residue EDO C 401 |
| Chain | Residue |
| C | LYS5 |
| C | SER7 |
| C | PHE129 |
| C | THR130 |
| C | HOH600 |
| D | LYS5 |
| D | MET6 |
| D | SER7 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 402 |
| Chain | Residue |
| C | PHE222 |
| C | GLN271 |
| C | HOH505 |
| C | HOH572 |
| C | HOH692 |
| C | HOH777 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 403 |
| Chain | Residue |
| C | TYR137 |
| C | TYR185 |
| C | GLY186 |
| C | ALA187 |
| C | HOH616 |
| C | HOH647 |
| C | HOH793 |
| site_id | AD3 |
| Number of Residues | 9 |
| Details | binding site for residue EDO C 404 |
| Chain | Residue |
| A | ASN226 |
| A | ARG227 |
| A | TYR267 |
| A | HOH515 |
| C | PHE106 |
| C | THR107 |
| C | THR108 |
| C | ASP181 |
| C | HOH508 |
| site_id | AD4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO C 405 |
| Chain | Residue |
| C | HIS8 |
| C | ALA114 |
| C | PHE115 |
| C | SER116 |
| C | THR130 |
| C | THR154 |
| C | HOH684 |
| C | HOH851 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 406 |
| Chain | Residue |
| C | ARG227 |
| C | SER229 |
| C | HOH620 |
| C | HOH802 |
| C | HOH912 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 401 |
| Chain | Residue |
| D | TRP221 |
| D | PHE222 |
| D | LYS224 |
| D | GLN271 |
| D | GLN277 |
| D | HOH573 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO D 402 |
| Chain | Residue |
| D | SER116 |
| D | THR130 |
| D | THR154 |
| D | HOH602 |
| D | HIS8 |
| D | ALA114 |
| D | PHE115 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 403 |
| Chain | Residue |
| D | GLU288 |
| D | ASP289 |
| D | GLU290 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 404 |
| Chain | Residue |
| D | GLY218 |
| D | CYS219 |
| D | ALA220 |
| D | TRP221 |
| D | HOH580 |
| D | HOH686 |
