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6JQD	The structural basis of the beta-carbonic anhydrase CafC (L25G and L78G mutant) of the filamentous fungus Aspergillus fumigatus Descriptor: Carbonic anhydrase, ZINC ION Authors: Jin, M.S, Kim, S, Kim, N.J, Hong, S, Kim, S, Sung, J. Deposit date: 2019-03-30 Release date: 2019-08-14 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.69 Å) Cite: The structural basis of the low catalytic activities of the two minor beta-carbonic anhydrases of the filamentous fungus Aspergillus fumigatus. J.Struct.Biol., 208, 2019
3E3G	H. influenzae beta-carbonic anhydrase, variant G41A Descriptor: Carbonic anhydrase 2, SULFATE ION, ZINC ION Authors: Rowlett, R.S, Failing, H. Deposit date: 2008-08-07 Release date: 2009-08-18 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Evidence for a bicarbonate "escort" site in Haemophilus influenzae beta-carbonic anhydrase . Biochemistry, 49, 2010
4YHA	Crystal structure of the complex of Helicobacter pylori alpha-Carbonic Anhydrase with methazolamide Descriptor: Alpha-carbonic anhydrase, CHLORIDE ION, GLYCEROL, ... Authors: Roujeinikova, A, Modak, J.K. Deposit date: 2015-02-27 Release date: 2015-07-01 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural Basis for the Inhibition of Helicobacter pylori alpha-Carbonic Anhydrase by Sulfonamides. Plos One, 10, 2015
3UCM	Coccomyxa beta-carbonic anhydrase in complex with thiocyanate Descriptor: Carbonic anhydrase, THIOCYANATE ION, ZINC ION Authors: Huang, S, Hainzl, T, Sauer-Eriksson, A.E. Deposit date: 2011-10-27 Release date: 2011-11-23 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.513 Å) Cite: Structural studies of [beta]-carbonic anhydrase from the green alga Coccomyxa: inhibitor complexes with anions and acetazolamide. Plos One, 6, 2011
3UCO	Coccomyxa beta-carbonic anhydrase in complex with iodide Descriptor: Carbonic anhydrase, IODIDE ION, ZINC ION Authors: Huang, S, Hainzl, T, Sauer-Eriksson, A.E. Deposit date: 2011-10-27 Release date: 2011-11-23 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural studies of [beta]-carbonic anhydrase from the green alga Coccomyxa: inhibitor complexes with anions and acetazolamide. Plos One, 6, 2011
3M1K	Carbonic Anhydrase in complex with fragment Descriptor: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 1-hydroxy-2-sulfanylpyridinium, Carbonic anhydrase 2, ... Authors: Schulze Wischeler, J, Heine, A, Klebe, G. Deposit date: 2010-03-05 Release date: 2010-11-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Bidentate Zinc chelators for alpha-carbonic anhydrases that produce a trigonal bipyramidal coordination geometry. Chemmedchem, 5, 2010
1CA2	REFINED STRUCTURE OF HUMAN CARBONIC ANHYDRASE II AT 2.0 ANGSTROMS RESOLUTION Descriptor: CARBONIC ANHYDRASE II, ZINC ION Authors: Eriksson, A.E, Jones, T.A, Liljas, A. Deposit date: 1989-02-06 Release date: 1990-01-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Refined structure of human carbonic anhydrase II at 2.0 A resolution. Proteins, 4, 1988
6KM3	Human Carbonic Anhydrase II native 00 atm CO2 Descriptor: Carbonic anhydrase 2, GLYCEROL, ZINC ION Authors: Kim, C.U, Kim, J.K. Deposit date: 2019-07-30 Release date: 2020-08-05 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.15 Å) Cite: Structural insights into the effect of active-site mutation on the catalytic mechanism of carbonic anhydrase. Iucrj, 7, 2020
6JQE	The structural basis of the beta-carbonic anhydrases CafD (wild type) of the filamentous fungus Aspergillus fumigatus Descriptor: Carbonic anhydrase, ZINC ION Authors: Jin, M.S, Kim, S, Kim, N.J, Hong, S, Kim, S, Sung, J. Deposit date: 2019-03-30 Release date: 2019-08-14 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The structural basis of the low catalytic activities of the two minor beta-carbonic anhydrases of the filamentous fungus Aspergillus fumigatus. J.Struct.Biol., 208, 2019
5CXK	Crystal structure of beta carbonic anhydrase from Vibrio cholerae Descriptor: BICARBONATE ION, Carbonic anhydrase, ZINC ION Authors: Ferraroni, M, Supuran, C. Deposit date: 2015-07-29 Release date: 2015-12-09 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure and kinetic studies of a tetrameric type II beta-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae. Acta Crystallogr.,Sect.D, 71, 2015
1CAN	CRYSTALLOGRAPHIC STUDIES OF THE BINDING OF PROTONATED AND UNPROTONATED INHIBITORS TO CARBONIC ANHYDRASE USING HYDROGEN SULPHIDE AND NITRATE ANIONS Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, NITRATE ION Authors: Mangani, S, Hakansson, K. Deposit date: 1992-07-02 Release date: 1994-01-31 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystallographic studies of the binding of protonated and unprotonated inhibitors to carbonic anhydrase using hydrogen sulphide and nitrate anions. Eur.J.Biochem., 210, 1992
3LXE	Human Carbonic Anhydrase I in complex with topiramate Descriptor: Carbonic anhydrase 1, ZINC ION, [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate Authors: Alterio, V, De Simone, G, Monti, S.M, Truppo, E. Deposit date: 2010-02-25 Release date: 2010-07-21 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The first example of a significant active site conformational rearrangement in a carbonic anhydrase-inhibitor adduct: the carbonic anhydrase I-topiramate complex. Org.Biomol.Chem., 2010
1BZM	DRUG-PROTEIN INTERACTIONS: STRUCTURE OF SULFONAMIDE DRUG COMPLEXED WITH HUMAN CARBONIC ANHYDRASE I Descriptor: CARBONIC ANHYDRASE I, N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide, ZINC ION Authors: Chakravarty, S, Kannan, K.K. Deposit date: 1993-11-28 Release date: 1994-04-30 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Drug-protein interactions. Refined structures of three sulfonamide drug complexes of human carbonic anhydrase I enzyme. J.Mol.Biol., 243, 1994
5JJ8	Crystal Structure of the Beta Carbonic Anhydrase psCA3 isolated from Pseudomonas aeruginosa - alternate crystal packing form Descriptor: Carbonic anhydrase, ZINC ION Authors: Pinard, M.A, Kurian, J.J, Aggarwal, M, Agbandje-McKenna, M, McKenna, R. Deposit date: 2016-04-22 Release date: 2016-07-06 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.585 Å) Cite: Cryoannealing-induced space-group transition of crystals of the carbonic anhydrase psCA3. Acta Crystallogr.,Sect.F, 72, 2016
3E31	H. influenzae beta-carbonic anhydrase, variant V47A Descriptor: Carbonic anhydrase 2, ZINC ION Authors: Rowlett, R.S, Lee, J. Deposit date: 2008-08-05 Release date: 2009-08-18 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Evidence for a bicarbonate "escort" site in Haemophilus influenzae beta-carbonic anhydrase . Biochemistry, 49, 2010
6YL7	Crystal structure of beta carbonic anhydrase from the pathogenic bacterium Burkholderia pseudomallei Descriptor: Beta carbonic anhydrase, ZINC ION Authors: Angeli, A, Ferraroni, M. Deposit date: 2020-04-06 Release date: 2020-06-10 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (3.17 Å) Cite: Crystal Structure of a Tetrameric Type II beta-Carbonic Anhydrase from the Pathogenic BacteriumBurkholderia pseudomallei. Molecules, 25, 2020
3E2X	H. influenzae beta-carbonic anhydrase, variant V47A Descriptor: Carbonic anhydrase 2, SULFATE ION, ZINC ION Authors: Rowlett, R.S, Lee, J. Deposit date: 2008-08-06 Release date: 2009-08-18 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Evidence for a bicarbonate "escort" site in Haemophilus influenzae beta-carbonic anhydrase . Biochemistry, 49, 2010
1CAO	CRYSTALLOGRAPHIC STUDIES OF THE BINDING OF PROTONATED AND UNPROTONATED INHIBITORS TO CARBONIC ANHYDRASE USING HYDROGEN SULPHIDE AND NITRATE ANIONS Descriptor: CARBONIC ANHYDRASE II, HYDROSULFURIC ACID, ZINC ION Authors: Mangani, S, Hakansson, K. Deposit date: 1992-07-02 Release date: 1994-01-31 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystallographic studies of the binding of protonated and unprotonated inhibitors to carbonic anhydrase using hydrogen sulphide and nitrate anions. Eur.J.Biochem., 210, 1992
6G3V	Crystal structure of human carbonic anhydrase I in complex with the inhibitor famotidine Descriptor: Carbonic anhydrase 1, GLYCEROL, ZINC ION, ... Authors: Ferraroni, M, Supuran, C.T, Angeli, A. Deposit date: 2018-03-26 Release date: 2018-11-28 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.69 Å) Cite: Famotidine, an Antiulcer Agent, Strongly InhibitsHelicobacter pyloriand Human Carbonic Anhydrases. ACS Med Chem Lett, 9, 2018
6G3Q	Crystal structure of human carbonic anhydrase II in complex with the inhibitor famotidine Descriptor: Carbonic anhydrase 2, GLYCEROL, ZINC ION, ... Authors: Ferraroni, M, Supuran, C.T, Angeli, A. Deposit date: 2018-03-26 Release date: 2018-11-28 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.01 Å) Cite: Famotidine, an Antiulcer Agent, Strongly InhibitsHelicobacter pyloriand Human Carbonic Anhydrases. ACS Med Chem Lett, 9, 2018
1LZV	Site-Specific Mutant (Tyr7 replaced with His) of Human Carbonic Anhydrase II Descriptor: Carbonic Anhydrase II, ZINC ION Authors: Tu, C.K, Qian, M, An, H, Wadhwa, N.R, Duda, D.M, Yoshioka, C, Pathak, Y, McKenna, R, Laipis, P.J, Silverman, D.N. Deposit date: 2002-06-11 Release date: 2002-10-23 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Kinetic analysis of multiple proton shuttles in the active site of human carbonic anhydrase. J.Biol.Chem., 277, 2002
3P5A	Human Carbonic Anhydrase complexed with Sodium morpholinocarbodithioate Descriptor: Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ZINC ION, ... Authors: Aggarwal, M, McKenna, R. Deposit date: 2010-10-08 Release date: 2011-10-19 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.49 Å) Cite: Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo J.Med.Chem., 55, 2012
6YJN	Crystal structure of beta carbonic anhydrase from the pathogenic bacterium Burkholderia pseudomallei. Descriptor: Beta carbonic anhydrase, ZINC ION Authors: Angeli, A, Ferraroni, M. Deposit date: 2020-04-03 Release date: 2020-06-10 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal Structure of a Tetrameric Type II beta-Carbonic Anhydrase from the Pathogenic BacteriumBurkholderia pseudomallei. Molecules, 25, 2020
3S75	The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase Descriptor: Carbonic anhydrase 2, ZINC ION, furan-2-sulfonamide Authors: Snyder, P.W, Heroux, A, Whitesides, G.W. Deposit date: 2011-05-26 Release date: 2011-10-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Mechanism of the hydrophobic effect in the biomolecular recognition of arylsulfonamides by carbonic anhydrase. Proc.Natl.Acad.Sci.USA, 108, 2011
4IDR	Human Carbonic Anhydrase II Proton Transfer Double Mutant Descriptor: Carbonic anhydrase 2, GLYCEROL, ZINC ION Authors: Mikulski, R.M, West, D.M. Deposit date: 2012-12-13 Release date: 2012-12-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Water Networks in Fast Proton Transfer during Catalysis by Human Carbonic Anhydrase II. Biochemistry, 52, 2013

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