1LZV
Site-Specific Mutant (Tyr7 replaced with His) of Human Carbonic Anhydrase II
Summary for 1LZV
Entry DOI | 10.2210/pdb1lzv/pdb |
Descriptor | Carbonic Anhydrase II, ZINC ION (3 entities in total) |
Functional Keywords | twisted beta sheet, zinc metalloenzyme, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29329.44 |
Authors | Tu, C.K.,Qian, M.,An, H.,Wadhwa, N.R.,Duda, D.M.,Yoshioka, C.,Pathak, Y.,McKenna, R.,Laipis, P.J.,Silverman, D.N. (deposition date: 2002-06-11, release date: 2002-10-23, Last modification date: 2024-02-14) |
Primary citation | Tu, C.,Qian, M.,An, H.,Wadhwa, N.R.,Duda, D.,Yoshioka, C.,Pathak, Y.,McKenna, R.,Laipis, P.J.,Silverman, D.N. Kinetic analysis of multiple proton shuttles in the active site of human carbonic anhydrase. J.Biol.Chem., 277:38870-38876, 2002 Cited by PubMed: 12171926DOI: 10.1074/jbc.M205791200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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