4YHA

Crystal structure of the complex of Helicobacter pylori alpha-Carbonic Anhydrase with methazolamide

Summary for 4YHA

• Entry DOI: 10.2210/pdb4yha/pdb
• Related: 4YGF
• Descriptor: Alpha-carbonic anhydrase, ZINC ION, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: zinc metalloenzyme, methazolamide, lyase
• Biological source: Helicobacter pylori
• Total number of polymer chains: 8
• Total formula weight: 219007.31

Authors

Roujeinikova, A.,Modak, J.K. (deposition date: 2015-02-27, release date: 2015-07-01, Last modification date: 2023-09-27)

• Primary citation: Modakh, J.K.,Liu, Y.C.,Machuca, M.A.,Supuran, C.T.,Roujeinikova, A.; Structural Basis for the Inhibition of Helicobacter pylori alpha-Carbonic Anhydrase by Sulfonamides.; Plos One, 10:e0127149-e0127149, 2015; PubMed: 26010545; DOI: 10.1371/journal.pone.0127149

Experimental method

X-RAY DIFFRACTION (2.2 Å)