4YHA
Crystal structure of the complex of Helicobacter pylori alpha-Carbonic Anhydrase with methazolamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Alpha-carbonic anhydrase | polymer | 234 | 27001.6 | 8 | UniProt (K4NGD4) Pfam (PF00194) UniProt (by SIFTS) (A0A0M3KL20) | Helicobacter pylori | |
| 2 | BA, FA, I, L, O... (G, H, A, B, C...) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 3 | CA, GA, J, M, P... (G, H, A, B, C...) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 4 | AA, DA, HA, K, N... (F, G, H, A, B...) | N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide | non-polymer | 236.3 | 8 | Chemie (MZM) | |||
| 5 | EA, R, U, Y (G, C, D, E) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 6 | IA, JA, KA, LA, MA... (A, B, C, D, E...) | water | water | 18.0 | 585 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 20 - 247 (UniProt: K4NGD4)
| PDB | External Database | Details |
|---|---|---|
| Gly 14 | - | expression tag |
| Ile 15 | - | expression tag |
| Asp 16 | - | expression tag |
| Pro 17 | - | expression tag |
| Phe 18 | - | expression tag |
| Thr 19 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 216012.8 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 2994.5 | |
| All* | Total formula weight | 219007.3 |
