6IC4
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6Q81
| Structure of P-glycoprotein(ABCB1) in the post-hydrolytic state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, P-glycoprotein (ABCB1) | Authors: | Ford, R.C, Thonghin, N, Collins, R.F, Barbieri, A, Shafi, T, Siebert, A. | Deposit date: | 2018-12-13 | Release date: | 2018-12-26 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (7.9 Å) | Cite: | Novel features in the structure of P-glycoprotein (ABCB1) in the post-hydrolytic state as determined at 7.9 angstrom resolution. Bmc Struct.Biol., 18, 2018
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6NLO
| Human ABCC6 NBD1 H812A in Apo state | Descriptor: | Multidrug resistance-associated protein 6, SULFATE ION | Authors: | Zheng, A, Thibodeau, P.H. | Deposit date: | 2019-01-08 | Release date: | 2020-01-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.85021973 Å) | Cite: | Structures of human ABCC6 NBD1 and NBD2 To be published
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6QEX
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6JB1
| Structure of pancreatic ATP-sensitive potassium channel bound with repaglinide and ATPgammaS at 3.3A resolution | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ... | Authors: | Chen, L, Ding, D, Wang, M, Wu, J.-X, Kang, Y. | Deposit date: | 2019-01-25 | Release date: | 2019-05-22 | Last modified: | 2021-09-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | The Structural Basis for the Binding of Repaglinide to the Pancreatic KATPChannel. Cell Rep, 27, 2019
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6JB3
| Structure of SUR1 subunit bound with repaglinide | Descriptor: | ATP-binding cassette sub-family C member 8 isoform X2, Digitonin, Repaglinide | Authors: | Chen, L, Ding, D, Wang, M, Wu, J.-X, Kang, Y. | Deposit date: | 2019-01-25 | Release date: | 2019-05-22 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.53 Å) | Cite: | The Structural Basis for the Binding of Repaglinide to the Pancreatic KATPChannel. Cell Rep, 27, 2019
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6JBJ
| Cryo-EM structure of human lysosomal cobalamin exporter ABCD4 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family D member 4 | Authors: | Xu, D, Feng, Z, Hou, W.T, Jiang, Y.L, Wang, L, Sun, L.F, Zhou, C.Z, Chen, Y. | Deposit date: | 2019-01-25 | Release date: | 2019-09-11 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structure of human lysosomal cobalamin exporter ABCD4. Cell Res., 29, 2019
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6O1V
| Complex of human cystic fibrosis transmembrane conductance regulator (CFTR) and GLPG1837 | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ... | Authors: | Zhang, Z, Liu, F, Chen, J, Levit, A, Shoichet, B. | Deposit date: | 2019-02-21 | Release date: | 2019-06-26 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural identification of a hotspot on CFTR for potentiation. Science, 364, 2019
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6O2P
| Complex of ivacaftor with cystic fibrosis transmembrane conductance regulator (CFTR) | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, ... | Authors: | Liu, F, Zhang, Z, Chen, J, Levit, A, Shoichet, B. | Deposit date: | 2019-02-24 | Release date: | 2019-06-26 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural identification of a hotspot on CFTR for potentiation. Science, 364, 2019
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6O30
| Lipid A transporter MsbA from Salmonella typhimurium | Descriptor: | Lipid A export ATP-binding/permease protein MsbA | Authors: | Padayatti, P.S, Zhang, Q, Wilson, I.A, Lee, S.C, Stanfield, R.L. | Deposit date: | 2019-02-25 | Release date: | 2019-06-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.47 Å) | Cite: | Structural Insights into the Lipid A Transport Pathway in MsbA. Structure, 27, 2019
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6QV2
| Structure of ATPgS-bound outward-facing TM287/288 in complex with nanobody Nb_TM#2 | Descriptor: | ABC transporter, ATP-binding protein, MAGNESIUM ION, ... | Authors: | Hutter, C.A.J, Huerlimann, L.M, Zimmermann, I, Egloff, P, Seeger, M.A. | Deposit date: | 2019-03-01 | Release date: | 2019-05-29 | Last modified: | 2019-06-05 | Method: | X-RAY DIFFRACTION (4.23 Å) | Cite: | The extracellular gate shapes the energy profile of an ABC exporter. Nat Commun, 10, 2019
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6QV1
| Structure of ATPgS-bound outward-facing TM287/288 in complex with nanobody Nb_TM1 | Descriptor: | ABC transporter, ATP-binding protein, MAGNESIUM ION, ... | Authors: | Hutter, C.A.J, Huerlimann, L.M, Zimmermann, I, Egloff, P, Seeger, M.A. | Deposit date: | 2019-03-01 | Release date: | 2019-05-29 | Last modified: | 2019-06-05 | Method: | X-RAY DIFFRACTION (3.48 Å) | Cite: | The extracellular gate shapes the energy profile of an ABC exporter. Nat Commun, 10, 2019
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6QUZ
| Structure of ATPgS-bound outward-facing TM287/288 in complex with sybody Sb_TM35 | Descriptor: | ABC transporter, ATP-binding protein, MAGNESIUM ION, ... | Authors: | Hutter, C.A.J, Huerlimann, L.M, Zimmermann, I, Egloff, P, Seeger, M.A. | Deposit date: | 2019-03-01 | Release date: | 2019-05-29 | Last modified: | 2019-06-05 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | The extracellular gate shapes the energy profile of an ABC exporter. Nat Commun, 10, 2019
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6QV0
| Structure of ATP-bound outward-facing TM287/288 in complex with sybody Sb_TM35 | Descriptor: | ABC transporter, ATP-binding protein, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Hutter, C.A.J, Huerlimann, L.M, Zimmermann, I, Egloff, P, Seeger, M.A. | Deposit date: | 2019-03-01 | Release date: | 2019-05-29 | Last modified: | 2019-06-05 | Method: | X-RAY DIFFRACTION (3.12 Å) | Cite: | The extracellular gate shapes the energy profile of an ABC exporter. Nat Commun, 10, 2019
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6R72
| Crystal structure of BmrA-E504A in an outward-facing conformation | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug exporter ATP-binding cassette | Authors: | Chaptal, V, Zampieri, V, Kilburg, A, Magnard, S, Falson, P. | Deposit date: | 2019-03-28 | Release date: | 2020-05-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.95 Å) | Cite: | Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter. Sci Adv, 8, 2022
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6R81
| Multidrug resistance transporter BmrA mutant E504A bound with ATP and Mg solved by Cryo-EM | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Lipid A export ATP-binding/permease protein MsbA, MAGNESIUM ION | Authors: | Wiseman, B, Chaptal, V, Zampieri, V, Magnard, S, Hogbom, M, Falson, P. | Deposit date: | 2019-03-30 | Release date: | 2020-05-06 | Last modified: | 2022-02-02 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter. Sci Adv, 8, 2022
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6R84
| Yeast Vms1 (Q295L)-60S ribosomal subunit complex (pre-state with Arb1) | Descriptor: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Su, T, Izawa, T, Cheng, J, Yamashita, Y, Berninghausen, O, Inada, T, Neupert, W, Beckmann, R. | Deposit date: | 2019-03-31 | Release date: | 2019-06-26 | Last modified: | 2019-07-10 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis. Nature, 570, 2019
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6RAM
| Heterodimeric ABC exporter TmrAB under turnover conditions in asymmetric unlocked return conformation with wider opened intracellular gate | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | Deposit date: | 2019-04-06 | Release date: | 2019-07-31 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
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6RAH
| Heterodimeric ABC exporter TmrAB in ATP-bound outward-facing open conformation | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance ABC transporter ATP-binding and permease protein, ... | Authors: | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | Deposit date: | 2019-04-06 | Release date: | 2019-07-31 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
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6RAG
| Heterodimeric ABC exporter TmrAB in inward-facing wide conformation under turnover conditions | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | Deposit date: | 2019-04-06 | Release date: | 2019-07-31 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
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6RAJ
| Heterodimeric ABC exporter TmrAB in vanadate trapped outward-facing open conformation | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ADP ORTHOVANADATE, MAGNESIUM ION, ... | Authors: | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | Deposit date: | 2019-04-06 | Release date: | 2019-07-31 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
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6RAN
| Heterodimeric ABC exporter TmrAB in inward-facing wide conformation | Descriptor: | Multidrug resistance ABC transporter ATP-binding and permease protein, Nanobody Nb9F10 | Authors: | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | Deposit date: | 2019-04-06 | Release date: | 2019-07-31 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
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6RAK
| Heterodimeric ABC exporter TmrAB in vanadate trapped outward-facing occluded conformation | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ADP ORTHOVANADATE, MAGNESIUM ION, ... | Authors: | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | Deposit date: | 2019-04-06 | Release date: | 2019-07-31 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
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6RAI
| Heterodimeric ABC exporter TmrAB in ATP-bound outward-facing occluded conformation | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance ABC transporter ATP-binding and permease protein, ... | Authors: | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | Deposit date: | 2019-04-06 | Release date: | 2019-07-31 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
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6RAF
| Heterodimeric ABC exporter TmrAB in inward-facing narrow conformation under turnover conditions | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Anti-vesicular stomatitis virus N VHH, ... | Authors: | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | Deposit date: | 2019-04-06 | Release date: | 2019-07-31 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
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