Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6O1V

Complex of human cystic fibrosis transmembrane conductance regulator (CFTR) and GLPG1837

Summary for 6O1V
Entry DOI10.2210/pdb6o1v/pdb
EMDB information0606
DescriptorCystic fibrosis transmembrane conductance regulator, Unknown Peptide, N-(3-carbamoyl-5,5,7,7-tetramethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-2-yl)-1H-pyrazole-3-carboxamide, ... (7 entities in total)
Functional Keywordsabc transporter, anion channel, cystic fibrosis, membrane protein, glpg1837, hydrolase
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight176415.82
Authors
Zhang, Z.,Liu, F.,Chen, J.,Levit, A.,Shoichet, B. (deposition date: 2019-02-21, release date: 2019-06-26, Last modification date: 2024-03-20)
Primary citationLiu, F.,Zhang, Z.,Levit, A.,Levring, J.,Touhara, K.K.,Shoichet, B.K.,Chen, J.
Structural identification of a hotspot on CFTR for potentiation.
Science, 364:1184-1188, 2019
Cited by
PubMed: 31221859
DOI: 10.1126/science.aaw7611
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.2 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon