6JB3

Structure of SUR1 subunit bound with repaglinide

Summary for 6JB3

• Entry DOI: 10.2210/pdb6jb3/pdb
• EMDB information: 9788
• Descriptor: ATP-binding cassette sub-family C member 8 isoform X2, Repaglinide, Digitonin (3 entities in total)
• Functional Keywords: katp, channel, repaglinide, kir, abc transporter, sur, membrane protein, diabetes, insulin secretagogue
• Biological source: Mesocricetus auratus (Golden hamster)
• Total number of polymer chains: 1
• Total formula weight: 178977.41

Authors

Chen, L.,Ding, D.,Wang, M.,Wu, J.-X.,Kang, Y. (deposition date: 2019-01-25, release date: 2019-05-22, Last modification date: 2021-09-29)

• Primary citation: Ding, D.,Wang, M.,Wu, J.X.,Kang, Y.,Chen, L.; The Structural Basis for the Binding of Repaglinide to the Pancreatic KATPChannel.; Cell Rep, 27:1848-1857.e4, 2019; PubMed: 31067468; DOI: 10.1016/j.celrep.2019.04.050

Experimental method

ELECTRON MICROSCOPY (3.001 Å)