3NBN
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1G1P
| NMR Solution Structures of delta-Conotoxin EVIA from Conus ermineus that Selectively Acts on Vertebrate Neuronal Na+ Channels | Descriptor: | CONOTOXIN EVIA | Authors: | Volpon, L, Lamthanh, H, Barbier, J, Gilles, N, Molgo, J, Menez, A, Lancelin, J.M. | Deposit date: | 2000-10-13 | Release date: | 2000-11-01 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | NMR Solution Structures of delta-Conotoxin EVIA from Conus ermineus That Selectively Acts on Vertebrate Neuronal Na+ Channels. J.Biol.Chem., 279, 2004
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6VY9
| Crystal structure of NotF prenyltransferase | Descriptor: | Deoxybrevianamide E synthase notF | Authors: | Dan, Q, Smith, J.L. | Deposit date: | 2020-02-25 | Release date: | 2021-02-03 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Data Science-Driven Analysis of Substrate-Permissive Diketopiperazine Reverse Prenyltransferase NotF: Applications in Protein Engineering and Cascade Biocatalytic Synthesis of (-)-Eurotiumin A. J.Am.Chem.Soc., 144, 2022
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2JUS
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1G1Z
| NMR Solution Structures of delta-Conotoxin EVIA from Conus ermineus that Selectively Acts on Vertebrate Neuronal Na+ Channels, LEU12-PRO13 Cis isomer | Descriptor: | CONOTOXIN EVIA | Authors: | Volpon, L, Lamthanh, H, Le Gall, F, Menez, A, Lancelin, J.M. | Deposit date: | 2000-10-16 | Release date: | 2000-11-01 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | NMR Solution Structures of delta-Conotoxin EVIA from Conus ermineus That Selectively Acts on Vertebrate Neuronal Na+ Channels. J.Biol.Chem., 279, 2004
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2JUT
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2JUR
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6RB5
| Trypanothione reductase in complex with 4-(((3-(8-(2-((1R,2S,5R)-6,6-dimethylbicyclo[3.1.1]heptan-2-yl)ethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)propyl)(methyl)amino)methyl)-4-hydroxypiperidine-1-carboximidamide | Descriptor: | 4-(((3-(8-(2-((1R,2S,5R)-6,6-dimethylbicyclo[3.1.1]heptan-2-yl)ethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)propyl)(methyl)amino)methyl)-4-hydroxypiperidine-1-carboximidamide, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Ilari, A, Fiorillo, A, Battista, T, Mocci, S. | Deposit date: | 2019-04-09 | Release date: | 2020-05-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.977 Å) | Cite: | Spiro-containing derivatives show antiparasitic activity against Trypanosoma brucei through inhibition of the trypanothione reductase enzyme. Plos Negl Trop Dis, 14, 2020
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2JUQ
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5AAN
| Crystal structure of Drosophila NCS-1 bound to penothiazine FD44 | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, CALCIUM ION, CG5907-PA, ... | Authors: | Chaves-Sanjuan, A, Infantes, L, Sanchez-Barrena, M.J. | Deposit date: | 2015-07-27 | Release date: | 2017-01-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Interference of the complex between NCS-1 and Ric8a with phenothiazines regulates synaptic function and is an approach for fragile X syndrome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1AG7
| CONOTOXIN GS, NMR, 20 STRUCTURES | Descriptor: | CONOTOXIN GS | Authors: | Hill, J.M, Alewood, P.F, Craik, D.J. | Deposit date: | 1997-04-03 | Release date: | 1998-04-08 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Solution structure of the sodium channel antagonist conotoxin GS: a new molecular caliper for probing sodium channel geometry. Structure, 5, 1997
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6KU5
| Notothenia coriiceps TRAF5 | Descriptor: | TRAF5 | Authors: | Park, H.H, Kim, C.M. | Deposit date: | 2019-08-30 | Release date: | 2020-07-08 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.299 Å) | Cite: | Structural and biochemical characterization of TRAF5 from Notothenia coriiceps and its implications in fish immune cell signaling. Fish Shellfish Immunol., 102, 2020
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5FYX
| Crystal structure of Drosophila NCS-1 bound to penothiazine FD16 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, FREQUENIN 2, ... | Authors: | Martinez-Gonzalez, L, Chaves-Sanjuan, A, Infantes, L, Sanchez-Barrena, M.J. | Deposit date: | 2016-03-10 | Release date: | 2017-01-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Interference of the complex between NCS-1 and Ric8a with phenothiazines regulates synaptic function and is an approach for fragile X syndrome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4R81
| NAD(P)H:quinone oxidoreductase from Methanothermobacter marburgensis | Descriptor: | FLAVIN MONONUCLEOTIDE, NADH dehydrogenase | Authors: | Ullmann, E, Tan, T.C, Herwig, C, Divne, C, Spadiut, O. | Deposit date: | 2014-08-29 | Release date: | 2014-11-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A novel cytosolic NADH:quinone oxidoreductase from Methanothermobacter marburgensis. Biosci.Rep., 34, 2014
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1CNN
| OMEGA-CONOTOXIN MVIIC FROM CONUS MAGUS | Descriptor: | OMEGA-CONOTOXIN MVIIC | Authors: | Nielsen, K.J, Adams, D, Thomas, L, Bond, T, Alewood, P.F, Craik, D.J, Lewis, R.J. | Deposit date: | 1999-05-20 | Release date: | 2000-05-31 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structure-activity relationships of omega-conotoxins MVIIA, MVIIC and 14 loop splice hybrids at N and P/Q-type calcium channels. J.Mol.Biol., 289, 1999
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3IPZ
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4ADW
| CRYSTAL STRUCTURE OF LEISHMANIA INFANTUM TRYPANOTHIONE REDUCTASE IN COMPLEX WITH NADPH AND TRYPANOTHIONE | Descriptor: | BIS(GAMMA-GLUTAMYL-CYSTEINYL-GLYCINYL)SPERMIDINE, FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Baiocco, P, Ilari, A, Colotti, G, Malatesta, F, Fiorillo, A. | Deposit date: | 2012-01-04 | Release date: | 2013-01-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.61 Å) | Cite: | Inhibition of Leishmania Infantum Trypanothione Reductase by Azole-Based Compounds: A Comparative Analysis with its Physiological Substrate by X-Ray Crystallography. Chemmedchem, 8, 2013
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3V79
| Structure of human Notch1 transcription complex including CSL, RAM, ANK, and MAML-1 on HES-1 promoter DNA sequence | Descriptor: | DNA 5'-D(*GP*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*AP*AP*A)-3', DNA 5'-D(*TP*TP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*TP*AP*AP*C)-3', Mastermind-like protein 1, ... | Authors: | Nam, Y, Sliz, P, Blacklow, S. | Deposit date: | 2011-12-20 | Release date: | 2012-02-15 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.85 Å) | Cite: | Conformational Locking upon Cooperative Assembly of Notch Transcription Complexes. Structure, 20, 2012
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2WOI
| Trypanothione reductase from Trypanosoma brucei | Descriptor: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, SODIUM ION, ... | Authors: | Alphey, M.S, Fairlamb, A.H. | Deposit date: | 2009-07-24 | Release date: | 2010-08-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Dihydroquinazolines as a Novel Class of Trypanosoma Brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of Their Binding Mode by Protein Crystallography. J.Med.Chem., 54, 2011
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2W53
| Structure of SmeT, the repressor of the Stenotrophomonas maltophilia multidrug efflux pump SmeDEF. | Descriptor: | REPRESSOR, SULFATE ION | Authors: | Mate, M.J, Romero, A, Hernandez, A, Martinez, J.L. | Deposit date: | 2008-12-04 | Release date: | 2009-04-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and Functional Analysis of Smet, the Repressor of the Stenotrophomonas Maltophilia Multidrug Efflux Pump Smedef. J.Biol.Chem., 284, 2009
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1ZLC
| Solution Conformation of alpha-conotoxin PIA | Descriptor: | Alpha-conotoxin PIA | Authors: | Chi, S.-W, Lee, S.-H, Kim, D.-H, Kim, J.-S, Olivera, B.M, McIntosh, J.M, Han, K.-H. | Deposit date: | 2005-05-05 | Release date: | 2006-05-02 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Solution structure of alpha-conotoxin PIA, a novel antagonist of alpha6 subunit containing nicotinic acetylcholine receptors Biochem.Biophys.Res.Commun., 338, 2005
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2IGU
| Deamidated analogue of ImI Conotoxin | Descriptor: | Alpha-conotoxin ImI | Authors: | Kini, R.M, Kang, T.S. | Deposit date: | 2006-09-25 | Release date: | 2007-08-14 | Last modified: | 2024-10-16 | Method: | SOLUTION NMR | Cite: | Protein folding determinants: structural features determining alternative disulfide pairing in alpha- and chi/lambda-conotoxins Biochemistry, 46, 2007
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2AJW
| Structure of the cyclic conotoxin MII-6 | Descriptor: | Alpha-conotoxin MII | Authors: | Clark, R.J, Fischer, H, Dempster, L, Daly, N.L, Rosengren, K.J, Nevin, S.T, Meunier, F.A, Adams, D.J, Craik, D.J. | Deposit date: | 2005-08-02 | Release date: | 2005-09-06 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the {alpha}-conotoxin MII. Proc.Natl.Acad.Sci.USA, 102, 2005
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2AK0
| Structure of cyclic conotoxin MII-7 | Descriptor: | Alpha-conotoxin MII | Authors: | Clark, R.J, Fischer, H, Dempster, L, Daly, N.L, Rosengren, K.J, Nevin, S.T, Meunier, F.A, Adams, D.J, Craik, D.J. | Deposit date: | 2005-08-02 | Release date: | 2005-09-06 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the {alpha}-conotoxin MII. Proc.Natl.Acad.Sci.USA, 102, 2005
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2GCZ
| Solution Structure of alpha-Conotoxin OmIA | Descriptor: | Alpha-conotoxin OmIA | Authors: | Chi, S.-W, Kim, D.-H, Olivera, B.M, McIntosh, J.M, Han, K.-H. | Deposit date: | 2006-03-15 | Release date: | 2006-07-25 | Last modified: | 2020-06-24 | Method: | SOLUTION NMR | Cite: | Solution conformation of a neuronal nicotinic acetylcholine receptor antagonist alpha-conotoxin OmIA that discriminates alpha3 vs. alpha6 nAChR subtypes Biochem.Biophys.Res.Commun., 345, 2006
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